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Frontiers in veterinary science2022; 9; 882423; doi: 10.3389/fvets.2022.882423

Comparative Analysis of Gut Microbiota Between Healthy and Diarrheic Horses.

Abstract: Increasing evidence reveals the importance of gut microbiota in animals for regulating intestinal homeostasis, metabolism, and host health. The gut microbial community has been reported to be closely related to many diseases, but information regarding diarrheic influence on gut microbiota in horses remains scarce. This study investigated and compared gut microbial changes in horses during diarrhea. The results showed that the alpha diversity of gut microbiota in diarrheic horses decreased observably, accompanied by obvious shifts in taxonomic compositions. The dominant bacterial phyla (, and ) and genera (, and ) in the healthy and diarrheic horses were same regardless of health status but different in abundances. Compared with the healthy horses, the relative abundances of , and in the diarrheic horses were observably decreased, whereas , and were dramatically increased. Moreover, diarrhea also resulted in a significant reduction in the proportions of 31 genera and a significant increase in the proportions of 14 genera. Taken together, this study demonstrated that the gut bacterial diversity and abundance of horses changed significantly during diarrhea. Additionally, these findings also demonstrated that the dysbiosis of gut microbiota may be an important driving factor of diarrhea in horses.
Copyright © 2022 Li, Lan, Zhang and Wang.
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Publication Date: 2022-05-02 PubMed ID: 35585860PubMed Central: PMC9108932DOI: 10.3389/fvets.2022.882423Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research paper investigates how a horse’s gut microbes change during bouts of diarrhea. The results reveal differences in diversity and abundance of gut bacteria in healthy horses versus those with diarrhea, suggesting that a shift in gut microbiota could drive the onset of diarrhea in horses.

Overview of Research

  • This study addresses a gap in scientific knowledge about the gut microbiota of horses and its relationship with diarrhea. Previous research shows that gut microbiota plays a crucial role in maintaining intestinal balance and overall health in animals, as well as contributing to various diseases. However, specific details about the impact of diarrhea on the gut microbiota of horses are limited.

Research Methodology and Findings

  • The research compared the gut microbial changes in horses during periods of diarrhea. It showed a significant decrease in the alpha diversity of gut microbiota in horses experiencing diarrhea, with distinct shifts in taxonomic compositions.
  • The dominant bacterial phyla and genera were the same in both healthy and diarrheic horses, but their abundances differed with health status.
  • Compared to healthy horses, those with diarrhea showed noticeable decreases in some bacterial species, while others increased dramatically.
  • The study also found a significant reduction in 31 genera and a substantial increase in 14 others due to diarrhea.

Conclusion and Implication of Findings

  • The findings demonstrate that horses’ gut bacterial diversity and abundance change significantly during diarrhea. The results suggest that gut microbiota dysbiosis, a microbial imbalance in the gut, could be a significant factor causing diarrhea in horses.
  • This research could guide further studies exploring the treatment and prevention of equine diarrhea by managing gut microbiota.

Cite This Article

APA
Li Y, Lan Y, Zhang S, Wang X. (2022). Comparative Analysis of Gut Microbiota Between Healthy and Diarrheic Horses. Front Vet Sci, 9, 882423. https://doi.org/10.3389/fvets.2022.882423

Publication

Frontiers in veterinary science
ISSN: 2297-1769
NlmUniqueID: 101666658
Country: Switzerland
Language: English
Volume: 9
Pages: 882423
PII: 882423

Researcher Affiliations

Li, Yaonan
  • Wuhan Business University, Wuhan, China.
Lan, Yanfang
  • Wuhan Business University, Wuhan, China.
Zhang, Shuang
  • Wuhan Business University, Wuhan, China.
Wang, Xiaoli
  • Wuhan Business University, Wuhan, China.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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