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Home / Equine Research Bank / Reprod Domest Anim / Comparative efficiency of oestrus synchronization in sheep w...
Reproduction in domestic animals = Zuchthygiene2020; 55(7); 882-884; doi: 10.1111/rda.13698

Comparative efficiency of oestrus synchronization in sheep with progesterone/eCG and progesterone/GnRH during breeding and non-breeding season.

Abstract: The present study compared the occurrence of oestrus behaviour and ovulation in response to the insertion of CIDR devices plus a classical treatment with equine chorionic gonadotrophin (eCG; single dose at CIDR removal) or alternative treatments with gonadotrophin-releasing hormone (GnRH, either in a single dose at 56 hr after CIDR removal, or in one dose at CIDR insertion and another dose at 56 hr after CIDR removal). The appearance of oestrus behaviour during reproductive season ranged between 84% and 95% and all females showing oestrus signs had subsequent ovulations. The response, during seasonal anoestrus, was similar in the group treated with eCG, but less than half of the females in the groups treated with GnRH showed oestrus signs in response to the treatment, although more than 80% of them showed resumption of ovulatory activity after the treatment. In conclusion, protocols based on GnRH administration offer similar yields to eCG-based protocols during the reproductive season but occurrence of oestrus in response to GnRH-based treatments is highly compromised during seasonal anoestrus.
© 2020 Blackwell Verlag GmbH.
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Publication Date: 2020-05-27 PubMed ID: 32383219DOI: 10.1111/rda.13698Google Scholar: Lookup
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  • Comparative Study
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research experimented on oestrus synchronization using two different hormones, progesterone/eCG and progesterone/GnRH, in sheep during breeding and non-breeding season. It found that progesterone/GnRH treatments yielded similar results with the breed season equivalent of progesterone/eCG, but was less effective during out of breeding season.

About the Study

  • This study aim is to understand the effectiveness of two hormonal protocols, progesterone combined with equine chorionic gonadotrophin (eCG) and progesterone combined with gonadotrophin-releasing hormone (GnRH), on oestrus synchronization in sheep.
  • In the experiment, the researchers compared the appearance of oestrus behaviour and ovulation in response to the insertion of controlled internal drug release (CIDR) devices plus eCG or GnRH treatments. oestrus behavior is the period of sexual receptivity in sheep and is a signal that the animal is ready to mate and could possibly conceive.
  • The GnRH treatment was administered either in a single dose 56 hours post CIDR removal, or split into two doses, one at CIDR insertion and the other 56 hours post CIDR removal.

Research Outcome

  • The study witnessed an range of 84% and 95% appearance of oestrus behaviour during the breeding season. Every female showing oestrus signs had subsequent ovulations indicating successful synchronization.
  • The effectiveness of both treatments was almost similar during seasonal anoestrus (the period when the animal is not in a reproductive phase), but the GnRH protocol showed less than half females responding with oestrus signs unlike eCG where this rate was significantly higher.
  • However, 80% of sheep subject to the GnRH treatment exhibited a resumption of ovulatory activity post treatment.

In Conclusion

  • The study concludes that during breeding season, GnRH administration can achieve sirnilar results to eCG-based protocols.
  • However, the occurrence of oestrus in response to GnRH-based treatments is highly inconsistent during seasonal anoestrus in comparison to eCG-based treatments.
  • Future research could explore why GnRH is less effective during the non-breeding season and identify possible solutions to enhance its effectiveness.

Cite This Article

APA
Santos-Jimenez Z, Martinez-Herrero C, Encinas T, Martinez-Ros P, Gonzalez-Bulnes A. (2020). Comparative efficiency of oestrus synchronization in sheep with progesterone/eCG and progesterone/GnRH during breeding and non-breeding season. Reprod Domest Anim, 55(7), 882-884. https://doi.org/10.1111/rda.13698

Publication

Reproduction in domestic animals = Zuchthygiene
ISSN: 1439-0531
NlmUniqueID: 9015668
Country: Germany
Language: English
Volume: 55
Issue: 7
Pages: 882-884

Researcher Affiliations

Santos-Jimenez, Zurisaday
  • Universidad Autónoma Agraria Antonio Narro, Torreón, Mexico.
  • Department of de Toxicologia y Farmacologia, Facultad de Veterinaria, UCM, Madrid, Spain.
Martinez-Herrero, Claudia
  • Department of Produccion y Sanidad Animal, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Encinas, Teresa
  • Department of de Toxicologia y Farmacologia, Facultad de Veterinaria, UCM, Madrid, Spain.
Martinez-Ros, Paula
  • Department of Produccion y Sanidad Animal, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Gonzalez-Bulnes, Antonio
  • Department of de Toxicologia y Farmacologia, Facultad de Veterinaria, UCM, Madrid, Spain.
  • Department of de Reproduccion Animal, INIA, Madrid, Spain.

MeSH Terms

  • Administration, Intravaginal
  • Animals
  • Chorionic Gonadotropin / administration & dosage
  • Chorionic Gonadotropin / pharmacology
  • Estrus Synchronization / methods
  • Female
  • Gonadotropin-Releasing Hormone / administration & dosage
  • Gonadotropin-Releasing Hormone / pharmacology
  • Ovulation / drug effects
  • Progesterone / administration & dosage
  • Progesterone / pharmacology
  • Seasons
  • Sheep, Domestic

References

This article includes 9 references
  1. Abecia JA, Forcada F, Gonzalez-Bulnes A. Hormonal control of reproduction in small ruminants. Animal Reproduction Science 130, 173-179.
    doi: 10.1016/j.anireprosci.2012.01.011google scholar: lookup
  2. Baird DT. Factors regulating the growth of the preovulatory follicle in sheep and human. Journal of Reproduction and Fertility 69, 343-352.
  3. Eppleston J, Evans G, Roberts EM. Effect of time of PMSG and GnRH on the time of ovulation, LH secretion and reproductive performance after intrauterine insemination with frozen ram semen. Animal Reproduction Science 26, 227-237.
    doi: 10.1016/0378-4320(91)90049-6google scholar: lookup
  4. Gonzalez-Bulnes A, Menchaca A, Martin GB, Martinez-Ros P. Seventy years of progestagen treatments for management of the sheep oestrous cycle: Where we are and where we should go. Reproduction, Fertility and Development 32, 441-452.
    doi: 10.1071/rd18477google scholar: lookup
  5. Martin GB, Oldham CM, Cognie Y, Pearce DT. The physiological responses of anovulatory ewes to the introduction of rams: A review. Livestock Production Science 15, 219-247.
    doi: 10.1016/0301-6226(86)90031-xgoogle scholar: lookup
  6. Martinez-Ros P, Astiz S, Garcia-Rosello E, Rios-Abellan A, Gonzalez-Bulnes A. Effects of short-term intravaginal progestagens on the onset and features of estrus, preovulatory LH surge and ovulation in sheep. Animal Reproduction Science 197, 317-323.
  7. Martinez-Ros P, Gonzalez-Bulnes A. Efficiency of CIDR-based protocols including GnRH instead of eCG for estrus synchronization in sheep. Animals 9, 146.
    doi: 10.3390/ani9040146google scholar: lookup
  8. Martinez-Ros P, Rios-Abellan A, Gonzalez-Bulnes A. Influence of progesterone-treatment length and eCG administration on appearance of estrous behavior, ovulatory success and fertility in sheep. Animals 9, 9.
  9. Thimonier J, Mauleon P. Variations saisonnieres du comportement d' oestrus et des activites ovarienne et hypophysaire chez les ovins. Annales De Biologie Animale, Biochimie, Biophysique 9, 233-250.

Citations

This article has been cited 4 times.
  1. Hashem NM, El-Hawy AS, El-Bassiony MF, El-Hamid ISA, Gonzalez-Bulnes A, Martinez-Ros P. Use of GnRH-Encapsulated Chitosan Nanoparticles as an Alternative to eCG for Induction of Estrus and Ovulation during Non-Breeding Season in Sheep.. Biology (Basel) 2023 Feb 22;12(3).
    doi: 10.3390/biology12030351pubmed: 36979043google scholar: lookup
  2. Santos-Jimenez Z, Meza-Herrera CA, Calderon-Leyva G, Martinez-Ros P, Guillen-Muñoz JM, Gonzalez-Bulnes A. Efficiency of hCG for Inducing Resumption of Ovarian Cyclicity and Synchronized Ovulations during the Seasonal Anestrous in Sheep.. Animals (Basel) 2021 Nov 5;11(11).
    doi: 10.3390/ani11113159pubmed: 34827891google scholar: lookup
  3. Pérez-Clariget R, López-Pérez Á, Ungerfeld R. Treatments with intravaginal sponges for estrous synchronization in ewes: length of the treatment, amount of medroxyprogesterone, and administration of a long-acting progesterone.. Trop Anim Health Prod 2021 Jun 5;53(3):345.
    doi: 10.1007/s11250-021-02798-wpubmed: 34091738google scholar: lookup
  4. Bruno-Galarraga M, Cano-Moreno V, Lago-Cruz B, Encinas T, Gonzalez-Bulnes A, Martinez-Ros P. The Use of hCG for Inducing Ovulation in Sheep Estrus Synchronization Impairs Ovulatory Follicle Growth and Fertility.. Animals (Basel) 2021 Apr 1;11(4).
    doi: 10.3390/ani11040984pubmed: 33915793google scholar: lookup
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