Comparison of phenylephrine administration and exercise versus phenylephrine administration and a rolling procedure for the correction of nephrosplenic entrapment of the large colon in horses: 88 cases (2004-2010).
Abstract: To compare the outcome of horses with nephrosplenic entrapment of the large colon (NSELC) that were treated nonsurgically by IV administration of phenylephrine and exercise with that of horses treated by IV administration of phenylephrine and a rolling procedure under general anesthesia. Methods: Retrospective case series. Methods: 88 horses with NSELC. Methods: Horses examined between 2004 and 2010 because of acute abdominal pain that had NSELC on the basis of findings on abdominal palpation per rectum, abdominal ultrasonography, or both were included. Medical records were reviewed to obtain information on treatment (IV administration of phenylephrine and exercise vs IV administration of phenylephrine and a rolling procedure) and outcome. Results: Overall, 85% (75/88) of horses with NSELC responded to exercise or rolling under general anesthesia. The success rate of rolling under general anesthesia (42/50 [84%]) was significantly higher than the success rate of exercise after IV administration of phenylephrine (24/38 [63.2%]). Resolution of NSELC was achieved by rolling under general anesthesia in 8 of 14 horses that initially failed to resolve with exercise. Conclusions: A rolling procedure performed under general anesthesia had a higher success rate than exercise after IV phenylephrine administration for resolution of NSELC in horses, suggesting that rolling could be considered as the initial medical treatment. The rolling procedure may be labor intensive and should only be attempted in a surgical facility in the event that exploratory laparotomy is required.
Publication Date: 2013-04-04 PubMed ID: 23547680DOI: 10.2460/javma.242.8.1146Google Scholar: Lookup
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Summary
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This research aimed to compare the effectiveness of two non-surgical treatment methods for nephrosplenic entrapment of the large colon (NSELC) in horses; one involving exercise after phenylephrine administration and the other a rolling procedure under general anesthesia after phenylephrine administration. The study found that the rolling procedure had a higher success rate.
Background and Purpose of the Research
- The research is built on the issue of nephrosplenic entrapment of the large colon (NSELC) in horses, which leads to acute abdominal pain. This medical condition is usually identified through abdominal palpation per rectum or abdominal ultrasonography.
- The objective of the study was to compare two nonsurgical treatments for NSELC – exercise after administration of phenylephrine, a medication that narrows blood vessels, and a rolling procedure performed under general anesthesia after the administration of phenylephrine.
Methods
- The study was a retrospective case series, meaning the researchers looked back at the records of patients who have already been treated.
- 88 horses diagnosed with NSELC and treated between 2004 and 2010 were chosen for this study.
- Details about the treatment (whether they received IV administration of phenylephrine and exercise or IV administration of phenylephrine and a rolling procedure) and the outcome were retrieved from their medical records for analysis.
Results
- The research found that overall, 85% of the horses responded to either exercise or the rolling procedure under anesthesia.
- The success rate of the rolling procedure under general anesthesia was significantly higher (84%) than that of exercise after the administration of phenylephrine (63.2%).
- The rolling method also worked for 8 of the 14 horses which did not respond to the exercise method initially.
Conclusion
- The researchers concluded that the higher success rate of the rolling procedure suggests this could be the preferred initial medical treatment.
- However, due to its labor-intensive nature, it was suggested that the procedure should only take place in a surgical facility in case an exploratory laparotomy is needed.
Cite This Article
APA
Fultz LE, Peloso JG, Giguère S, Adams AR.
(2013).
Comparison of phenylephrine administration and exercise versus phenylephrine administration and a rolling procedure for the correction of nephrosplenic entrapment of the large colon in horses: 88 cases (2004-2010).
J Am Vet Med Assoc, 242(8), 1146-1151.
https://doi.org/10.2460/javma.242.8.1146 Publication
Researcher Affiliations
- Equine Medical Center of Ocala, 7107 W. Highway 326, Ocala, FL 34482, USA.
MeSH Terms
- Anesthesia, General / veterinary
- Animals
- Colon / pathology
- Horse Diseases / therapy
- Horses
- Intestinal Obstruction / therapy
- Intestinal Obstruction / veterinary
- Phenylephrine / therapeutic use
- Physical Conditioning, Animal
- Retrospective Studies
- Sympathomimetics / therapeutic use
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