Complement fixing antibodies against arboviruses in horses at Lagos, Nigeria.
Abstract: Sixty-two sera horse collected from two stables at Lagos, Nigeria, were tested for complement fixing antibody to 8 arbovirus antigens; Chikungunya, Igbo-Ora, Yellow fever, Wesselsbron, West Nile, Potiskum, Uganda S and Rift Valley fever. Ten per cent of the horse sera examined contained CF antibody to one or more of the test antigens and indicated considerable arbovirus activity in the two stables. Reactions with flavivirus antigens were most common and the highest antibody titres were obtained with Wesselsbron and Yellow fever viruses. Eleven per cent of the sera tested reacted with alphavirus antigens while 10 per cent were positive for Rift Valley fever virus CF antibodies.
Publication Date: 1989-01-01 PubMed ID: 2485538
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- Journal Article
Summary
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The research article discusses a study focused on the detection of antibodies for different types of arboviruses in horses from two stables in Lagos, Nigeria.
Research Method and Analysis
- The study was conducted with a total of sixty-two horse serums collected from two specific stables in Lagos, Nigeria.
- These sera were tested for complement fixing (CF) antibodies to eight different arbovirus antigens. These antigens included Chikungunya, Igbo-Ora, Yellow fever, Wesselsbron, West Nile, Potiskum, Uganda S and Rift Valley fever.
- The complement fixing antibody test is a method used to understand the presence of specific antigens or antibodies in the patient’s blood. The presence of CF antibodies indicates a previous or current infection.
Research Findings
- The results of the test revealed that 10% of the horse sera examined contained CF antibodies to one or more of the test antigens presented.
- This finding led to the conclusion that there is significant arbovirus activity in the two stables where the samples were collected.
- Reactions with flavivirus antigens were found to be the most common among the horses tested. These are a group of viruses that include Yellow fever, West Nile, and Wesselsbron viruses. Furthermore, the highest antibody titres were obtained with Wesselsbron and Yellow fever viruses.
- About 11% of the tested sera reacted with alphavirus antigens. Alphavirus is a group of viruses that includes the Chikungunya and Igbo-Ora viruses.
- Around 10% of the serums tested positive for Rift Valley fever virus CF antibodies. Rift Valley fever is a viral zoonosis that primarily affects animals but can also infect humans.
Conclusion
- The study’s outcomes suggest a noteworthy presence of various types of arboviruses in the horse population of the researched stables in Lagos, Nigeria.
- The presence of these viruses not only affects the health of the animals, but also poses significant public health risks, as many arboviruses are zoonotic, meaning they can be transmitted from animals to humans.
Cite This Article
APA
Olaleye OD, Oladosu LA, Omilabu SA, Baba SS, Fagbami AH.
(1989).
Complement fixing antibodies against arboviruses in horses at Lagos, Nigeria.
Rev Elev Med Vet Pays Trop, 42(3), 321-325.
Publication
Researcher Affiliations
- Department of Virology, College of Medicine, University of Ibadan, Nigeria.
MeSH Terms
- Animals
- Antibodies, Viral / analysis
- Arbovirus Infections / veterinary
- Arboviruses / immunology
- Complement Fixation Tests
- Horse Diseases / epidemiology
- Horses
- Nigeria
Citations
This article has been cited 9 times.- Olufemi OT, Barba M, Daly JM. A Scoping Review of West Nile Virus Seroprevalence Studies among African Equids. Pathogens 2021 Jul 15;10(7).
- Agboli E, Zahouli JBZ, Badolo A, Jöst H. Mosquito-Associated Viruses and Their Related Mosquitoes in West Africa. Viruses 2021 May 12;13(5).
- Mahmoud HYAH, Ali AO. Epidemiology and serological detection of Rift Valley Fever disease in farm animals in southern Egypt. Onderstepoort J Vet Res 2021 Feb 3;88(1):e1-e5.
- Onoja AB, Maina MM, Opayele AV. Molecular Identification and Phylogenetic Analysis of Acetylcholinesterase-2 Gene From Culex pipiens And Culex quinquefasciatus (Diptera: Culicine) in Nigeria. Niger Vet J 2018;39(4):285-294.
- Oluwayelu D, Adebiyi A, Tomori O. Endemic and emerging arboviral diseases of livestock in Nigeria: a review. Parasit Vectors 2018 Jun 7;11(1):337.
- Victor OA, Adekunle AJ, Tahiru IK, David OO. Influence of Meteorological Variables on Diversity and Abundance of Mosquito Vectors in Two Livestock Farms in Ibadan, Nigeria: Public Health Implications. J Mosq Res 2017;7(9):70-78.
- Ayorinde A, Oboh B, Oduola A, Otubanjo O. The Insecticide Susceptibility Status of Aedes aegypti (Diptera: Culicidae) in Farm and Nonfarm Sites of Lagos State, Nigeria. J Insect Sci 2015;15(1).
- Sule WF, Oluwayelu DO, Adedokun RA, Rufai N, McCracken F, Mansfield KL, Johnson N. High seroprevelance of West Nile virus antibodies observed in horses from southwestern Nigeria. Vector Borne Zoonotic Dis 2015 Mar;15(3):218-20.
- Vourc'h G, Halos L, Desvars A, Boué F, Pascal M, Lecollinet S, Zientara S, Duval T, Nzonza A, Brémont M. Chikungunya antibodies detected in non-human primates and rats in three Indian Ocean islands after the 2006 ChikV outbreak. Vet Res 2014 May 1;45(1):52.
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