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The Veterinary clinics of North America. Equine practice2025; 41(3); 595-618; doi: 10.1016/j.cveq.2025.08.008

Complications in the Critically Ill Equine Patient.

Abstract: Complications in critically ill equine patients are often related to the underlying disease process but can also be a consequence of diagnostic and therapeutic interventions. Complications can be specific to the affected organ or body system; however, in critically ill patients, they frequently affect the vasculature, acid-base, electrolyte, and fluid balance, energy homeostasis, and coagulation, with systemic consequences. Infrequent monitoring, late detection, failure to adapt therapies, hematologic and biochemical abnormalities, coagulopathies, and systemic inflammation can all contribute to processes that worsen the prognosis. Reducing the impact of complications through accurate clinical evaluations as well as a good understanding of physiology, pathophysiology, data interpretation, and therapeutics ultimately improve the outcome of the critically ill equine patient.
Publication Date: 2025-09-26 PubMed ID: 41015718DOI: 10.1016/j.cveq.2025.08.008Google Scholar: Lookup
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Summary

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Overview

  • This research article focuses on the complications that occur in critically ill horses, emphasizing that these complications often stem from the primary illness but can also arise due to medical interventions.
  • The study highlights the importance of monitoring, understanding physiological processes, and adapting treatments to improve the survival and recovery of severely ill equine patients.

Detailed Explanation

Nature and Origin of Complications

  • Complications in critically ill equine patients are frequently linked to the underlying disease affecting the horse.
  • They may also result from diagnostic procedures or therapeutic interventions, which can introduce additional risks or side effects.
  • Complications can be localized to the affected organ or body system or may have systemic effects.

Common Systems and Functions Affected

  • Key physiological systems often impacted include:
    • Vascular system: Problems with blood vessels can affect circulation and tissue oxygenation.
    • Acid-base balance: Disruptions can lead to metabolic imbalances and affect cellular function.
    • Electrolyte and fluid balance: Imbalances here can cause serious disturbances in muscle, nerve function, and overall homeostasis.
    • Energy homeostasis: The body’s ability to maintain energy production and consumption is critical in recovery.
    • Coagulation: Abnormal clotting or bleeding can complicate the clinical picture.

Factors Contributing to Worsened Prognosis

  • Failure to perform frequent and appropriate monitoring leads to delayed recognition of complications.
  • Late detection of issues prevents timely intervention and increases the risk of deterioration.
  • Not adjusting therapies in response to changing patient conditions limits treatment effectiveness.
  • Hematologic (blood) and biochemical abnormalities can both indicate and exacerbate critical illness.
  • Coagulopathies (clotting disorders) and systemic inflammation further complicate recovery and increase mortality risk.

Strategies to Improve Outcomes

  • Accurate and frequent clinical evaluations are essential to identify early signs of complications.
  • A strong understanding of equine physiology and pathophysiology supports better interpretation of clinical data.
  • Interpreting diagnostic tests properly allows clinicians to adjust treatments effectively.
  • Optimizing therapeutic interventions based on ongoing assessments helps minimize complications.
  • Overall, reducing the impact of complications through these approaches enhances the survival and health of critically ill horses.

Cite This Article

APA
Mazur SE, Toribio RE. (2025). Complications in the Critically Ill Equine Patient. Vet Clin North Am Equine Pract, 41(3), 595-618. https://doi.org/10.1016/j.cveq.2025.08.008

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 41
Issue: 3
Pages: 595-618
PII: S0749-0739(25)00051-3

Researcher Affiliations

Mazur, Sarah E
  • College of Veterinary Medicine, The Ohio State University, 601 Vernon Tharp Street, Columbus, OH 43210, USA.
Toribio, Ramiro E
  • College of Veterinary Medicine, The Ohio State University, 601 Vernon Tharp Street, Columbus, OH 43210, USA. Electronic address: toribio.1@osu.edu.

MeSH Terms

  • Animals
  • Horses
  • Horse Diseases / therapy
  • Horse Diseases / diagnosis
  • Horse Diseases / etiology
  • Critical Illness / therapy

Conflict of Interest Statement

Disclosure The authors have nothing to disclose.

Citations

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