Congenital stationary night blindness in a Thoroughbred and a Paso Fino.
Abstract: This report documents congenital stationary night blindness (CSNB) in two non-Appaloosa horse breeds (Thoroughbred and Paso Fino). History of vision impairment since birth, normal ocular structures on ophthalmic examination, and electroretinographic findings were consistent with CSNB. In one horse (Thoroughbred), a 9-year follow-up was carried out. In the Paso Fino, severe vision impairment from birth to approximately 1 year of age in both dim and bright light situations led to humane euthanasia and histopathologic confirmation of the disorder.
Publication Date: 2005-12-20 PubMed ID: 16359365DOI: 10.1111/j.1463-5224.2005.00416.xGoogle Scholar: Lookup
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Summary
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The research article discusses the occurrence of congenital stationary night blindness (CSNB), an inherited vision impairment, in two horses from the Thoroughbred and Paso Fino breeds.
Objective and Methodology
- The primary objective of this study was to document cases of Congenital stationary night blindness (CSNB) in two non-Appaloosa horse breeds, specifically Thoroughbred and Paso Fino.
- The researchers used methods such as recording the horses’ vision impairment history since their birth, conducting ophthalmic examinations, and using electroretinographic findings in their research.
Findings
- The research found that the symptoms and results from these methods were consistent with CSNB.
- In the case of the Thoroughbred, the researchers did a 9-year follow-up and continued to find these consistent results.
- The Paso Fino, on the other hand, had severe vision impairment since birth, which continued into its first year. This impairment was present in both dim and bright light situations.
Conclusion and Further Actions
- Due to the severity of the vision impairment in the Paso Fino, the decision was made for humane euthanasia.
- Following this, a histopathologic examination was conducted which confirmed the diagnosis of CSNB.
- The research thus provided valuable insight into the occurrence of CSNB in non-Appaloosa horse breeds, paving the way for further studies in this area.
Cite This Article
APA
Nunnery C, Pickett JP, Zimmerman KL.
(2005).
Congenital stationary night blindness in a Thoroughbred and a Paso Fino.
Vet Ophthalmol, 8(6), 415-419.
https://doi.org/10.1111/j.1463-5224.2005.00416.x Publication
Researcher Affiliations
- Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0442, USA.
MeSH Terms
- Animals
- Breeding
- Electroretinography / methods
- Electroretinography / veterinary
- Fatal Outcome
- Horse Diseases / congenital
- Horse Diseases / pathology
- Horses
- Male
- Night Blindness / congenital
- Night Blindness / pathology
- Night Blindness / veterinary
- Retinal Cone Photoreceptor Cells / physiopathology
- Visual Acuity
Citations
This article has been cited 4 times.- Ignacio C, Del Mar LM, Marta B, Sina Z, Vicent R, Aloma MF. Comparison of two sedation protocols for long electroretinography in horses using the Koijman electrode.. BMC Vet Res 2023 Aug 4;19(1):106.
- Bellone RR, Holl H, Setaluri V, Devi S, Maddodi N, Archer S, Sandmeyer L, Ludwig A, Foerster D, Pruvost M, Reissmann M, Bortfeldt R, Adelson DL, Lim SL, Nelson J, Haase B, Engensteiner M, Leeb T, Forsyth G, Mienaltowski MJ, Mahadevan P, Hofreiter M, Paijmans JL, Gonzalez-Fortes G, Grahn B, Brooks SA. Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness and leopard complex spotting in the horse.. PLoS One 2013;8(10):e78280.
- Brosnahan MM, Brooks SA, Antczak DF. Equine clinical genomics: A clinician's primer.. Equine Vet J 2010 Oct;42(7):658-70.
- Webb AA, Cullen CL. Coat color and coat color pattern-related neurologic and neuro-ophthalmic diseases.. Can Vet J 2010 Jun;51(6):653-7.
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