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Contagious equine metritis: clinical description of experimentally induced infection.

Abstract: Contagious equine metritis was reproduced experimentally in 6 pony mares. The disease was characterized by rapidly developing cervicitis and by varying amounts of exudate. The exudate, apparent as early as 48 hours after inoculation, drained from the cervix as a tenacious, mucopurulent discharge for several days, then rapidly disappeared. In all mares, the clinical disease cleared within several weeks of inoculation, without treatment.
Publication Date: 1978-08-15 PubMed ID: 689984
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  • Journal Article

Summary

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This study experimentally induced contagious equine metritis in six pony mares to analyse the development, characteristics, and self-healing of the condition.

Introduction to the Research

  • The research paper focused on the understanding of contagious equine metritis, a highly contagious venereal disease in horses.
  • Scientists induced the infection in six pony mares for this study. This facilitated a direct and controlled observation of the progression and possible self-healing of the disease.

Characteristics of the disease

  • The disease was characterized by rapidly developing cervicitis, an inflammation of the cervix. This condition became evident within a short time after the infection was induced.
  • An exudate, a fluid emitted by an organism through pores or a wound, a result of inflammation or disease, was observed among the symptoms. The quantity of this exudate varied among the mares.
  • The exudate was seen as soon as 48 hours following inoculation, presenting as a tenacious, mucopurulent discharge from the cervix.
  • This discharge persisted for a few days before subsiding rapidly.

Recovery from the disease

  • In spite of the rapid onset and progression of the disease, recovery was also quite fast. This led researchers to the conclusion that the disease is self-limiting in nature.
  • All the mares under the study had beaten the infection within a few weeks of inoculation without treatment.
  • The study did not administer any treatment to the infected mares, to observe the natural course and possible self-resolution of the disease.

Significance of the study

  • The value of the research lies in its insights into the progression and self-healing nature of contagious equine metritis.
  • It can guide further studies and treatment strategies for managing this disease in horses, emphasizing the potential of the immune response of these animals in overcoming this infection.

Cite This Article

APA
Pierson RE, Sahu SP, Dardiri AH, Wilder FW. (1978). Contagious equine metritis: clinical description of experimentally induced infection. J Am Vet Med Assoc, 173(4), 402-404.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 173
Issue: 4
Pages: 402-404

Researcher Affiliations

Pierson, R E
    Sahu, S P
      Dardiri, A H
        Wilder, F W

          MeSH Terms

          • Animals
          • Bacterial Infections / veterinary
          • Endometritis / veterinary
          • Female
          • Fever / veterinary
          • Horse Diseases
          • Horses
          • Suppuration
          • Uterine Cervicitis / veterinary

          Citations

          This article has been cited 1 times.
          1. Bertram TA, Coignoul FL, Jensen AE. Phagocytosis and intracellular killing of the contagious equine metritis organism by equine neutrophils in serum. Infect Immun 1982 Sep;37(3):1241-7.