Continuous digital hypothermia for prevention and treatment of equine acute laminitis: A practical review.
Abstract: Laminitis is a severely debilitating and life-threatening condition that occurs as a consequence of different primary triggering factors. Continuous digital hypothermia (CDH) is recommended in horses at risk of, or diagnosed with, acute laminitis due to its several physiological and biochemical alterations that may be positive for the prevention and early treatment of the condition, representing a low risk of adverse effects. Modulation of the inflammatory response, profound vasoconstriction, and prevention of tissue damage are the most notable protective effects of cryotherapy on the lamellae. This practical review aims to summarize the published literature evaluating CDH efficacy in the prevention and early treatment of acute laminitis in horses, highlighting the most important clinical findings and discussing the best methods to provide cryotherapy. Nineteen publications evaluated different CDH methods, including the use of commercially available ice boots or fluid bags filled with iced water or crushed ice, as well as alternatives to immersion in ice, e.g., frozen gel packs and a perfused cuff prototype. Although some techniques were effective for cooling and maintaining the hooves below the optimal temperature of 10 °C, relevant limitations such as labor intensiveness, reliance on an ice source and price make its use impractical in some clinical situations. Twelve experimental studies assessed the efficacy of CDH on the prevention or early treatment of laminitis, finding multiple positive effects in terms of clinical improvement, immunological and inflammatory modulation, and histological protection. After the analysis of the literature, the clinical importance of CDH in different stages of laminitis remains clear. However, it also highlights the need for a safer, more user-friendly, and more effective method of cryotherapy that can be used both in a hospital and an ambulatory setting.
Copyright © 2023 Elsevier Ltd. All rights reserved.
Publication Date: 2023-07-26 PubMed ID: 37507002DOI: 10.1016/j.tvjl.2023.106016Google Scholar: Lookup
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Summary
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The research article presents a comprehensive evaluation of Continuous Digital Hypothermia (CDH) as a preventive and early treatment measure for acute laminitis in horses. The researchers review various methods used to administer CDH, their effectiveness, and limitations, emphasizing the need for more efficient approaches.
Understanding Laminitis and CDH
- Laminitis is a severe condition in horses associated with various triggering factors, potentially leading to death.
- Continuous Digital Hypothermia (CDH), which involves cooling the hoof area, has been recommended as a preventive measure and early treatment strategy for this condition.
- CDH’s benefits lie in its ability to modify the inflammatory response, prevent tissue damage, and cause profound vasoconstriction. All these can have desirable protective effects on the animal’s lamellae (the soft, sensitive layer inside the horse’s hoof).
Methods of CDH Application Evaluated
- The research analyzed different methods of providing CDH. They included commercial ice boots, fluid bags filled with cold water or crushed ice, as well as frozen gel packs, and a novel perfused cuff prototype.
- Though some of these methods effectively cooled the hooves to temperatures below the ideal 10 °C mark, they were criticized for being laborious, costly, and over-reliant on an ice source.
Literary Analysis and Findings
- The researchers assessed nineteen published works that evaluated CDH’s effectiveness in preventing and treating laminitis in horses.
- Twelve experimental studies showed CDH could bring multiple positives, such as clinical improvements, immunological and inflammatory modulation, as well as histological protection for the horse’s lamellae.
- The reviewed literature reaffirmed the vital role of CDH in managing different laminitis stages but also illuminated the need for more effective, safe, and user-friendly CDH application strategies that could be deployed both in hospital and ambulatory settings.
Cite This Article
APA
Lavado RA, Lewis J, Montgomery JB.
(2023).
Continuous digital hypothermia for prevention and treatment of equine acute laminitis: A practical review.
Vet J, 300-302, 106016.
https://doi.org/10.1016/j.tvjl.2023.106016 Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; Department of Medical Clinic, University of São Paulo, São Paulo, SP 05508-900, Brazil.
- Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; Department of Agriculture, Angelo State University, San Angelo, TX 76909, USA.
- Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada. Electronic address: julia.montgomery@usask.ca.
MeSH Terms
- Animals
- Horses
- Hypothermia / therapy
- Hypothermia / veterinary
- Inflammation / prevention & control
- Inflammation / veterinary
- Ice
- Horse Diseases / prevention & control
- Horse Diseases / pathology
- Foot Diseases / prevention & control
- Foot Diseases / veterinary
- Hypothermia, Induced / veterinary
Conflict of Interest Statement
Declaration of Competing Interest None of the authors have any financial or personal relationships that could inappropriately influence or bias the content of the paper.
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