Corneal thickness, intraocular pressure, and optical corneal diameter in Rocky Mountain Horses with cornea globosa or clinically normal corneas.
Abstract: To compare corneal thickness, intraocular pressure, and optical corneal diameter in Rocky Mountain Horses with cornea globosa and those with clinically normal corneas. Methods: 129 Rocky Mountain Horses. Methods: Ultrasonic pachymetry was used to measure corneal thickness. Applanation tonometry was used to measure intraocular pressure. A Jameson caliper was used to measure optical corneal diameter. Results: The central and temporal peripheral portions of the cornea were significantly thicker in horses with cornea globosa than in horses with clinically normal corneas, but corneal thicknesses in the dorsal, ventral, and medial peripheral portions of the cornea were not significantly different between groups. There were no differences in corneal thickness between male and female horses or between right and left eyes. However, there was a positive correlation between age and corneal thickness. Intraocular pressure was not significantly different between horses with cornea globosa and those with clinically normal corneas, or between right and left eyes, or male and female horses. Optical corneal diameter for horses with cornea globosa was not significantly different from diameter for horses with clinically normal corneas, but optical corneal diameter was positively correlated with age. Conclusions: Cornea globosa in Rocky Mountain Horses is not associated with increased intraocular pressure. Corneal thickness and optical corneal diameter increase with age in Rocky Mountain Horses.
Publication Date: 2000-05-03 PubMed ID: 10791948
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- Journal Article
Summary
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The research article investigates the differences in corneal thickness, intraocular pressure, and optical corneal diameter between Rocky Mountain Horses with a condition called cornea globosa and horses with normal corneas. The results indicate that cornea globosa does not lead to increased intraocular pressure, and both corneal thickness and optical corneal diameter increase with age in these horses.
Research Purpose and Methods
- The study primarily aims to examine and compare the corneal thickness, intraocular pressure (pressure within the eye), and optical corneal diameter (size of the cornea) between Rocky Mountain Horses affected by cornea globosa and those with clinically normal corneas.
- A total of 129 Rocky Mountain Horses were included in this study.
- For measuring corneal thickness, ultrasonic pachymetry was utilized. This tool allows the precise calculation of the thickness of the cornea using ultrasound technology.
- To measure the intraocular pressure, applanation tonometry was applied, a method that effectively gauges the fluid pressure inside the eye.
- Optical corneal diameter was measured using a Jameson caliper, an instrument traditionally used in optometry and ophthalmology to measure the eye’s physical features.
Research Findings
- The study found that the central and peripheral parts of the cornea in horses with cornea globosa were significantly thicker than in horses with normal corneas. However, the thickness in other parts of the cornea was not significantly different between the two groups.
- Notably, corneal thickness did not vary significantly based on gender or between the right and left eyes of the horses.
- Interestingly, the study revealed a positive correlation between age and corneal thickness, meaning older horses tend to have thicker corneas.
- In contrast, no significant difference was found in intraocular pressure between horses with and without cornea globosa, between the eyes, or between genders.
- Similarly to corneal thickness, the study found that optical corneal diameter also increases with age in Rocky Mountain Horses. Despite this, the diameter was not significantly different between horses with or without cornea globosa.
Conclusions drawn from the Research
- A crucial conclusion of this research is that cornea globosa in Rocky Mountain Horses is not associated with an increase in intraocular pressure. This means that this specific condition does not cause a higher fluid pressure inside the eye.
- Another significant finding is that both corneal thickness and optical corneal diameter increase as these horses age. This implies that certain changes in the horses’ eyes are part of their natural aging process rather than being linked solely to diseases.
Cite This Article
APA
Ramsey DT, Hauptman JG, Petersen-Jones SM.
(2000).
Corneal thickness, intraocular pressure, and optical corneal diameter in Rocky Mountain Horses with cornea globosa or clinically normal corneas.
Am J Vet Res, 60(10), 1317-1321.
Publication
Researcher Affiliations
- Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824-1314, USA.
MeSH Terms
- Aging
- Animals
- Cornea / abnormalities
- Cornea / anatomy & histology
- Cornea / growth & development
- Eye Abnormalities / veterinary
- Female
- Horse Diseases / pathology
- Horses
- Intraocular Pressure
- Male
- Regression Analysis
Citations
This article has been cited 8 times.- Knickelbein KE, Lassaline ME, Kim S, Scharbrough MS, Thomasy SM. Corneal thickness and anterior chamber depth of the normal adult horse as measured by ultrasound biomicroscopy. Vet Ophthalmol 2022 May;25 Suppl 1(Suppl 1):17-24.
- Mohamed A, Nankivil D, Pesala V, Taneja M. The precision of ophthalmic biometry using calipers. Can J Ophthalmol 2013 Dec;48(6):506-11.
- Andersson LS, Wilbe M, Viluma A, Cothran G, Ekesten B, Ewart S, Lindgren G. Equine multiple congenital ocular anomalies and silver coat colour result from the pleiotropic effects of mutant PMEL. PLoS One 2013;8(9):e75639.
- Komáromy AM, Rowlan JS, La Croix NC, Mangan BG. Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five cases. Vet Ophthalmol 2011 Sep;14(5):313-20.
- Andersson LS, Lyberg K, Cothran G, Ramsey DT, Juras R, Mikko S, Ekesten B, Ewart S, Lindgren G. Targeted analysis of four breeds narrows equine Multiple Congenital Ocular Anomalies locus to 208 kilobases. Mamm Genome 2011 Jun;22(5-6):353-60.
- Sandmeyer LS, Grahn BH. Diagnostic ophthalmology. Can Vet J 2009 Mar;50(3):319-20.
- Andersson LS, Juras R, Ramsey DT, Eason-Butler J, Ewart S, Cothran G, Lindgren G. Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6. BMC Genet 2008 Dec 19;9:88.
- Grahn BH, Pinard C, Archer S, Bellone R, Forsyth G, Sandmeyer LS. Congenital ocular anomalies in purebred and crossbred Rocky and Kentucky Mountain horses in Canada. Can Vet J 2008 Jul;49(7):675-81.
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