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Home / Equine Research Bank / Trop Anim Health Prod / Correlations of corpus luteum blood flow with fertility and ...
Tropical animal health and production2021; 53(2); 280; doi: 10.1007/s11250-021-02583-9

Correlations of corpus luteum blood flow with fertility and progesterone in embryo recipient mares.

Abstract: The aim of this study was to evaluate the correlation between the corpus luteum vascularization with the concentration of progesterone and the fertility of embryo recipient mares. Mangalarga Marchador mares (n = 33) were distributed into groups according to the days (D) after ovulation, as follows: D3 (n = 8), D4 (n = 8), D5 (n = 9), and D6 (n = 8). The evaluations of the corpus luteum, endometrium, and blood collection to quantify the progesterone concentration were carried out on D3, D4, D5, and D6. Among the parameters evaluated, only progesterone concentration on D6 differed from the other groups (P <0.05). A positive correlation (P <0.05) between the diameter and the area of the corpus luteum, and the objective and subjective methods of the corpus luteum vascular perfusion, was identified. Likewise, a positive correlation (P <0.05) was observed between the objective and subjective methods of the vascular perfusion in the corpus luteum and the progesterone concentration. The pregnancy rate obtained in this study (54.54%) was not affected (P> 0.05) by the day of embryo transfer, whose percentages were 37.50% (3/8) on D3, 50% (4/8) on D4, 66.70% (6/9) on D5, and 62.50% (5/8) on D6. It was estimated that with each increase on the day of embryo transfer, the pregnancy rate increases. The results allow to conclude that the corpus luteum vascularization in mares, evaluated by Doppler ultrasound, correlates with progesterone concentration and the embryo transfer day.
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Publication Date: 2021-04-22 PubMed ID: 33885987DOI: 10.1007/s11250-021-02583-9Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research aimed to investigate the relationship between the blood flow in the corpus luteum of mares, their progesterone levels, and their fertility following embryo transfer.

Objective and Study Design

  • The principal objective of this study was to explore the correlation between the vascularization of the corpus luteum (a structure that plays a critical role in female fertility) and the concentration of progesterone (a hormone important for maintaining pregnancy), as well as the fertility of embryo recipient mares.
  • The study involved a breed of horse called Mangalarga Marchador mares. A total of 33 of these mares were included in the research and grouped according to the days after ovulation: Day 3, Day 4, Day 5, and Day 6.

Methodology

  • The researchers evaluated the development of the corpus luteum, the endometrium (the lining of the uterus), and drew blood samples for progesterone level determination. These evaluations were conducted on days 3, 4, 5, and 6 after ovulation.
  • Additionally, Doppler ultrasound was used to assess corpus luteum’s vascular perfusion or blood flow.

Key Findings

  • The results showed that there was a significant difference in the concentration of progesterone on the sixth day after ovulation compared to other days.
  • A positive correlation was found between the size of the corpus luteum and its blood flow. Moreover, the blood flow in the corpus luteum and progesterone concentration had a positive correlation as well.
  • The pregnancy rates were not significantly impacted by the day of embryo transfer. The transfer’s success rate tended to increase with each later day of the transfer, but this trend did not reach statistical significance.

Conclusion

  • According to the authors conclusions, the blood flow in the corpus luteum, as assessed by Doppler ultrasound, correlated with progesterone concentration and the day on which the embryo transfer was conducted.
  • This helps in understanding how the structure and function of the corpus luteum can impact the outcome of embryo transfer procedures in horses. The findings could potentially guide the timing of embryo transfers to maximize the chances of a successful pregnancy.

Cite This Article

APA
Sales FABM, Azevedo MV, Souza NM, Ferreira-Silva JC, Chaves MS, Junior VR, Rocha JM, Dos Santos Filho JP, Freitas VJF, Oliveira MAL. (2021). Correlations of corpus luteum blood flow with fertility and progesterone in embryo recipient mares. Trop Anim Health Prod, 53(2), 280. https://doi.org/10.1007/s11250-021-02583-9

Publication

Tropical animal health and production
ISSN: 1573-7438
NlmUniqueID: 1277355
Country: United States
Language: English
Volume: 53
Issue: 2
Pages: 280

Researcher Affiliations

Sales, Felipe Augusto Boudoux Martins
  • Reproductive Biotechnics Laboratory, Federal Rural University of Pernambuco, Recife, PE, Brazil.
Azevedo, Marlon Vasconcelos
  • Reproductive Biotechnics Laboratory, Federal Rural University of Pernambuco, Recife, PE, Brazil.
Souza, Natalia Matos
  • Department of Veterinary Medicine, Federal University of Campina Grande, Areias, PB, Brazil.
Ferreira-Silva, José Carlos
  • Reproductive Biotechnics Laboratory, Federal Rural University of Pernambuco, Recife, PE, Brazil.
Chaves, Maiana Silva
  • Faculty of Veterinary Medicine, State University of Ceará, Fortaleza, CE, Brazil.
Junior, Valdir Riberio
  • Reproductive Biotechnics Laboratory, Federal Rural University of Pernambuco, Recife, PE, Brazil.
Rocha, Jorge Motta
  • Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Dos Santos Filho, José Pompeu
  • Reproductive Biotechnics Laboratory, Federal Rural University of Pernambuco, Recife, PE, Brazil.
Freitas, Vicente José de Figueirêdo
  • Faculty of Veterinary Medicine, State University of Ceará, Fortaleza, CE, Brazil.
Oliveira, Marcos Antonio Lemos
  • Reproductive Biotechnics Laboratory, Federal Rural University of Pernambuco, Recife, PE, Brazil. maloufrpe@gmail.com.

MeSH Terms

  • Animals
  • Corpus Luteum
  • Embryo Transfer / veterinary
  • Female
  • Fertility
  • Horses
  • Ovulation
  • Pregnancy
  • Progesterone

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Citations

This article has been cited 1 times.
  1. Requena F, Campos MJAPM, Martínez Marín AL, Camacho R, Giráldez-Pérez RM, Agüera EI. Assessment of Age Effects on Ovarian Hemodynamics Using Doppler Ultrasound and Progesterone Concentrations in Cycling Spanish Purebred Mares. Animals (Basel) 2021 Aug 8;11(8).
    doi: 10.3390/ani11082339pubmed: 34438797google scholar: lookup
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