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Cryotherapy of periocular squamous cell carcinoma in the horse.

Abstract: Squamous cell carcinoma around the eyes of 3 horses was treated with liquid nitrogen, using cryotherapy probes as the method of application. In 2 cases, there was complete regression of the tumor; in the 3rd case, remission and relief of discomfort were temporary.
Publication Date: 1977-06-01 PubMed ID: 863777
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Summary

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The research article discusses an experiment where liquid nitrogen was applied to squamous cell carcinoma around the eyes of three horses using cryotherapy probes and monitored for results.

Experiment Overview

  • The experiment explored the treatment of squamous cell carcinoma located near the eyes of horses using cryotherapy, a primarily non-surgical method that utilizes extreme cold to destroy diseased tissue.

Method of Application

  • The research implemented the use of cryotherapy probes. These tools administer the ultra-cold treatment directly to the affected area.
  • The cryogen used in the research was liquid nitrogen, a substance commonly utilized in cryotherapy procedures due to its extremely low boiling point which results in the freezing and destruction of the targeted cells.

Results

  • The treatment resulted in a complete regression of the tumor in two of the cases. This suggests that cryotherapy could be a successful treatment method for periocular squamous cell carcinomas in horses.
  • The third case experienced temporary remission and relief from discomfort. However, the treatment failed to result in a permanent regression of the tumor, indicating that the procedure’s effectiveness can vary across different cases. This may depend on factors such as the size, location, or stage of the cancer.

Conclusion

  • The research concluded that cryotherapy could potentially serve as an effective treatment for squamous cell carcinoma around the eyes in horses.
  • However, more detailed study is necessary to understand the varying effectiveness of the treatment across different cases and to determine the precise factors that might influence the success of the treatment.

Cite This Article

APA
Hilbert BJ, Farrell RK, Grant BD. (1977). Cryotherapy of periocular squamous cell carcinoma in the horse. J Am Vet Med Assoc, 170(11), 1305-1308.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 170
Issue: 11
Pages: 1305-1308

Researcher Affiliations

Hilbert, B J
    Farrell, R K
      Grant, B D

        MeSH Terms

        • Animals
        • Carcinoma, Squamous Cell / pathology
        • Carcinoma, Squamous Cell / therapy
        • Carcinoma, Squamous Cell / veterinary
        • Cryosurgery / methods
        • Cryosurgery / veterinary
        • Eyelid Neoplasms / pathology
        • Eyelid Neoplasms / therapy
        • Eyelid Neoplasms / veterinary
        • Female
        • Horse Diseases / pathology
        • Horse Diseases / therapy
        • Horses
        • Male
        • Nictitating Membrane / pathology

        Citations

        This article has been cited 1 times.
        1. Jeanes EC, Koll-Hampp S, Dawson C, Dunkel B, Tetas Pont R. Rhomboid blepharoplasty and cryotherapy for the treatment of a squamous cell carcinoma on the lower eyelid in a horse. Clin Case Rep 2019 Jan;7(1):40-46.
          doi: 10.1002/ccr3.1907pubmed: 30656005google scholar: lookup