Cryptosporidiosis in immunodeficient Arabian foals.
Abstract: Five of six immunodeficient Arabian foals that died of adenoviral infection were found to be infected with an intestinal coccidian of the genus Cryptosporidium. Various developmental stages of the organism were found in the microvillous border of the intestinal mucosa. The foals had diarrhea but it was not possible to separate the effects of the cryptosporidial infection from those of the concomitant adenoviral enteritis.
Publication Date: 1978-01-01 PubMed ID: 625861DOI: 10.1177/030098587801500102Google Scholar: Lookup
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- Journal Article
- Research Support
- U.S. Gov't
- P.H.S.
Summary
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The study examines the occurrence of Cryptosporidiosis, a parasitic infection, in Arabian foals (young horses) that were immunodeficient and died from an adenoviral infection. The research discovered that out of six foals, five had the Cryptosporidium parasite within their intestinal mucosa.
Background
- Cryptosporidiosis is a disease caused by a microscopic parasite called Cryptosporidium. This organism infects the intestinal tract and can cause diarrhoea in its host.
- The study was conducted on Arabian foals, particularly those who are immunodeficient or have a weak immune system, making them vulnerable to infections and diseases.
Findings
- Out of the six immunodeficient Arabian foals that died of adenoviral infections, five were infected with Cryptosporidium.
- The different development stages of the Cryptosporidium parasite were found along the microvillous border of the intestinal mucosa in the foals. The microvillous border refers to the small, finger-like extensions that increase the surface area of the intestine, allowing greater nutrient absorption.
Implications
- In this study, all foals exhibited diarrhoea, a common symptom of Cryptosporidium. However, it was not possible to determine whether the diarrhoea was solely due to the Cryptosporidium infection or if it was a combined effect of the adenoviral infection and the Cryptosporidiosis.
- The study gives insight into the susceptibility of immunodeficient Arabian foals to parasitic infections. Further research is required to determine the extent to which Cryptosporidium contributes to illness and mortality in this demographic.
Cite This Article
APA
Snyder SP, England JJ, McChesney AE.
(1978).
Cryptosporidiosis in immunodeficient Arabian foals.
Vet Pathol, 15(1), 12-17.
https://doi.org/10.1177/030098587801500102 Publication
Researcher Affiliations
MeSH Terms
- Animals
- Coccidia / ultrastructure
- Coccidiosis / complications
- Coccidiosis / veterinary
- Horse Diseases / microbiology
- Horses
- Immunologic Deficiency Syndromes / complications
- Immunologic Deficiency Syndromes / veterinary
- Intestines / microbiology
- Intestines / ultrastructure
Citations
This article has been cited 24 times.- Li XM, Geng HL, Wei YJ, Yan WL, Liu J, Wei XY, Zhang M, Wang XY, Zhang XX, Liu G. Global prevalence and risk factors of Cryptosporidium infection in Equus: A systematic review and meta-analysis.. Front Cell Infect Microbiol 2022;12:1072385.
- Ghafar A, Abbas G, King J, Jacobson C, Hughes KJ, El-Hage C, Beasley A, Bauquier J, Wilkes EJA, Hurley J, Cudmore L, Carrigan P, Tennent-Brown B, Nielsen MK, Gauci CG, Beveridge I, Jabbar A. Comparative studies on faecal egg counting techniques used for the detection of gastrointestinal parasites of equines: A systematic review.. Curr Res Parasitol Vector Borne Dis 2021;1:100046.
- Couso-Pérez S, de Limia FB, Ares-Mazás E, Gómez-Couso H. First report of zoonotic Cryptosporidium parvum GP60 subtypes IIaA15G2R1 and IIaA16G3R1 in wild ponies from the northern Iberian Peninsula.. Parasitol Res 2020 Jan;119(1):249-254.
- Deng L, Li W, Zhong Z, Gong C, Cao X, Song Y, Wang W, Huang X, Liu X, Hu Y, Fu H, He M, Wang Y, Zhang Y, Wu K, Peng G. Occurrence and Genetic Characteristics of Cryptosporidium hominis and Cryptosporidium andersoni in Horses from Southwestern China.. J Eukaryot Microbiol 2017 Sep;64(5):716-720.
- Liu A, Zhang J, Zhao J, Zhao W, Wang R, Zhang L. The first report of Cryptosporidium andersoni in horses with diarrhea and multilocus subtype analysis.. Parasit Vectors 2015 Sep 22;8:483.
- Wagnerová P, Sak B, McEvoy J, Rost M, Matysiak AP, Ježková J, Kváč M. Genetic diversity of Cryptosporidium spp. including novel identification of the Cryptosporidium muris and Cryptosporidium tyzzeri in horses in the Czech Republic and Poland.. Parasitol Res 2015 Apr;114(4):1619-24.
- Gajadhar AA, Caron JP, Allen JR. Cryptosporidiosis in two foals.. Can Vet J 1985 Apr;26(4):132-4.
- Majewska AC, Solarczyk P, Tamang L, Graczyk TK. Equine Cryptosporidium parvum infections in western Poland.. Parasitol Res 2004 Jul;93(4):274-8.
- Granstrom DE. Recent advances in the laboratory diagnosis of equine parasitic diseases.. Vet Clin North Am Equine Pract 1995 Dec;11(3):437-42.
- Guarino A, Canani RB, Pozio E, Terracciano L, Albano F, Mazzeo M. Enterotoxic effect of stool supernatant of Cryptosporidium-infected calves on human jejunum.. Gastroenterology 1994 Jan;106(1):28-34.
- Xiao L, Herd RP. Review of equine Cryptosporidium infection.. Equine Vet J 1994 Jan;26(1):9-13.
- Tzipori S, Angus KW, Campbell I, Gray EW. Cryptosporidium: evidence for a single-species genus.. Infect Immun 1980 Dec;30(3):884-6.
- Pearson GR, Logan EF, McNulty MS. Distribution of cryptosporidia within the gastrointestinal tract of young calves.. Res Vet Sci 1982 Sep;33(2):228-31.
- Tzipori S, Campbell I. Prevalence of Cryptosporidium antibodies in 10 animal species.. J Clin Microbiol 1981 Oct;14(4):455-6.
- Tzipori S. Cryptosporidiosis in animals and humans.. Microbiol Rev 1983 Mar;47(1):84-96.
- Angus KW. Cryptosporidiosis in man, domestic animals and birds: a review.. J R Soc Med 1983 Jan;76(1):62-70.
- Anderson BC. Moist heat inactivation of Cryptosporidium sp.. Am J Public Health 1985 Dec;75(12):1433-4.
- Palmer JE. Gastrointestinal diseases of foals.. Vet Clin North Am Equine Pract 1985 Apr;1(1):151-68.
- Rodgers VD, Kagnoff MF. Gastrointestinal manifestations of the acquired immunodeficiency syndrome.. West J Med 1987 Jan;146(1):57-67.
- Riggs MW, Perryman LE. Infectivity and neutralization of Cryptosporidium parvum sporozoites.. Infect Immun 1987 Sep;55(9):2081-7.
- Fayer R, Ungar BL. Cryptosporidium spp. and cryptosporidiosis.. Microbiol Rev 1986 Dec;50(4):458-83.
- Tzipori S. Cryptosporidiosis in perspective.. Adv Parasitol 1988;27:63-129.
- Perryman LE, Riggs MW, Mason PH, Fayer R. Kinetics of Cryptosporidium parvum sporozoite neutralization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum.. Infect Immun 1990 Jan;58(1):257-9.
- Bjorneby JM, Leach DR, Perryman LE. Persistent cryptosporidiosis in horses with severe combined immunodeficiency.. Infect Immun 1991 Oct;59(10):3823-6.
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