Analyze Diet
The Veterinary clinics of North America. Small animal practice2017; 48(2); 323-338; doi: 10.1016/j.cvsm.2017.10.010

Current and Newly Emerging Autoimmune Diseases.

Abstract: There are many autoimmune diseases that are recognized in domestic animals. The descriptions of diseases provide examples of the magnitude of immune targets and the variable nature of autoimmune diseases. Other autoimmune diseases that are recognized in dogs, cats, and horses include immune-mediated thrombocytopenia, VKH (Vogt-Koyanagi-Harada) ocular disease (dogs), and Evans syndrome (which includes both immune-mediated anemia and immune-mediated thrombocytopenia).
Publication Date: 2017-12-14 PubMed ID: 29248206DOI: 10.1016/j.cvsm.2017.10.010Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article
  • Review

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research paper discusses a variety of recognized autoimmune diseases in domestic animals such as dogs, cats, and horses, including their immune targets and variable nature.

Overview of Recognized Autoimmune Diseases

The paper highlights autoimmune diseases in domestic animals, specifically dogs, cats, and horses. These conditions involve the animal’s immune system attacking its own tissues. The paper discusses how these diseases exhibit variable nature and provide insight into the vast range of immune targets.

  • Examples of such diseases include immune-mediated thrombocytopenia (a condition where the body’s immune system targets and destroys platelets needed to form blood clots); VKH (Vogt-Koyanagi-Harada) ocular disease, a canine eye disease; and Evans syndrome (a condition involving both immune-mediated anemia, where the immune system targets and destroys red blood cells, and immune-mediated thrombocytopenia).

Understanding Immune Targets and Variable Nature

Different autoimmune diseases target different parts of the animal’s body. This research seeks to provide insight into the considerable range of these immune targets. Each autoimmune disease has its unique characteristics and presents differently in each animal, emphasizing the variable, complex nature of these conditions.

  • An understanding of the immune targets related to each condition can contribute to more effective diagnostics, treatments, and ultimately, improved animal health.
  • Knowledge of the variable nature of these diseases can lead to the development of more personalized treatment plans for each individual animal suffering from an autoimmune disease.

Significance of this Research

This research is important as it helps veterinarians and researchers better understand the intricacies of autoimmune diseases in domestic animals. The research offers descriptions of diseases, which can be useful for identifying symptoms, making diagnoses, and creating effective treatment plans.

  • By understanding more about these diseases, veterinary professionals can potentially improve prognosis and enhance quality of life for domestic animals suffering from these conditions.
  • This research also opens doors for further studies into immune targets, enhancing the scientific community’s understanding of these illnesses and potentially helping to refine treatment approaches in the future.

Cite This Article

APA
Gershwin LJ. (2017). Current and Newly Emerging Autoimmune Diseases. Vet Clin North Am Small Anim Pract, 48(2), 323-338. https://doi.org/10.1016/j.cvsm.2017.10.010

Publication

ISSN: 1878-1306
NlmUniqueID: 7809942
Country: United States
Language: English
Volume: 48
Issue: 2
Pages: 323-338
PII: S0195-5616(17)30140-7

Researcher Affiliations

Gershwin, Laurel J
  • Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Vet Med 3A, Davis, CA 95616, USA. Electronic address: ljgershwin@ucdavis.edu.

MeSH Terms

  • Animals
  • Autoimmune Diseases / drug therapy
  • Autoimmune Diseases / genetics
  • Autoimmune Diseases / immunology
  • Autoimmune Diseases / veterinary
  • Cat Diseases / diagnosis
  • Cat Diseases / drug therapy
  • Cat Diseases / genetics
  • Cats
  • Dog Diseases / diagnosis
  • Dog Diseases / drug therapy
  • Dog Diseases / genetics
  • Dogs
  • Horse Diseases / immunology
  • Horses

Citations

This article has been cited 6 times.
  1. Chen WJ, Yu X, Yuan XR, Chen BJ, Cai N, Zeng S, Sun YS, Li HW. The Role of IL-36 in the Pathophysiological Processes of Autoimmune Diseases.. Front Pharmacol 2021;12:727956.
    doi: 10.3389/fphar.2021.727956pubmed: 34675805google scholar: lookup
  2. Wang JH, Liu XL, Sun JM, Yang JH, Xu DH, Yan SS. Role of mesenchymal stem cell derived extracellular vesicles in autoimmunity: A systematic review.. World J Stem Cells 2020 Aug 26;12(8):879-896.
    doi: 10.4252/wjsc.v12.i8.879pubmed: 32952864google scholar: lookup
  3. Knapp DW, Dhawan D, Ramos-Vara JA, Ratliff TL, Cresswell GM, Utturkar S, Sommer BC, Fulkerson CM, Hahn NM. Naturally-Occurring Invasive Urothelial Carcinoma in Dogs, a Unique Model to Drive Advances in Managing Muscle Invasive Bladder Cancer in Humans.. Front Oncol 2019;9:1493.
    doi: 10.3389/fonc.2019.01493pubmed: 32039002google scholar: lookup
  4. Mikelez-Alonso I, Aires A, Cortajarena AL. Cancer Nano-Immunotherapy from the Injection to the Target: The Role of Protein Corona.. Int J Mol Sci 2020 Jan 14;21(2).
    doi: 10.3390/ijms21020519pubmed: 31947622google scholar: lookup
  5. Furlanello T, Reale I. Leptospirosis and immune-mediated hemolytic anemia: A lethal association.. Vet Res Forum 2019 Summer;10(3):261-265.
    doi: 10.30466/vrf.2019.99876.2385pubmed: 31737237google scholar: lookup
  6. Sommer BC, Dhawan D, Ratliff TL, Knapp DW. Naturally-Occurring Canine Invasive Urothelial Carcinoma: A Model for Emerging Therapies.. Bladder Cancer 2018 Apr 26;4(2):149-159.
    doi: 10.3233/BLC-170145pubmed: 29732386google scholar: lookup