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Frontiers in veterinary science2021; 8; 648774; doi: 10.3389/fvets.2021.648774

Current Concepts in Fluid Therapy in Horses.

Abstract: Despite the frequent inclusion of fluid therapy in the treatment of many conditions in horses, there are limited studies available to provide evidenced-based, species-specific recommendations. Thus, equine fluid therapy is based on the application of physiology and extrapolation from evidence in other veterinary species and human medicine. The physiologic principles that underly the use of fluids in medicine are, at first glance, straightforward and simple to understand. However, in the past 20 years, multiple studies in human medicine have shown that creating recommendations based on theory in combination with experimental and/or small clinical studies does not consistently result in best practice. As a result, there are ongoing controversies in human medicine over fluid types, volumes, and routes of administration. For example, the use of 0.9% NaCl as the replacement fluid of choice is being questioned, and the theoretical benefits of colloids have not translated to clinical cases and negative effects are greater than predicted. In this review, the current body of equine research in fluid therapy will be reviewed, connections to the controversies in human medicine and other veterinary species will be explored and, where appropriate, recommendations for fluid therapy in the adult horse will be made based on the available evidence. This review is focused on the decisions surrounding developing a fluid plan involving crystalloids, synthetic colloids, and plasma.
Copyright © 2021 Crabtree and Epstein.
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Publication Date: 2021-03-29 PubMed ID: 33855057PubMed Central: PMC8039297DOI: 10.3389/fvets.2021.648774Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article discusses the current understanding and challenges in fluid therapy for horses, comparing this with findings from human medicine and other veterinary studies. It notes that while fluid therapy is often used to treat horses, the lack of horse-specific, evidence-based studies presents complications in determining best practices.

Understanding Fluid Therapy in Horses

The study discusses the prominent use of fluid therapy in managing many horse conditions and how, due to limited research specific to the equine species, practitioners predominantly rely on:

  • The application of physiology principles
  • Extrapolation from findings in other veterinary species and human medicine

Controversies in Fluid Therapy

Differences from the theoretical understanding and actual outcomes have resulted in ongoing controversies in fluid therapy. Among these are issues related to:

  • The types of fluid to be used
  • Determination of fluid volumes
  • Routes of administration

For instance, the study mentions that the use of 0.9% NaCl (normal saline) is currently being debated as the go-to replacement fluid. Furthermore, the theoretical benefits of colloids aren’t consistently witnessed in clinical case, with negative effects more pronounced than expected.

Existing Research and Connection to Other Disciplines

The paper aims to review existing horse-specific research on fluid therapy and relate these findings to the controversies in human medicine and other animal studies. It also provided recommendations on fluid therapy for adult horses wherever adequate evidence was available. The focus stays on decisions revolving around developing a fluid plan which typically includes crystalloids, synthetic colloids, and plasma.

Cite This Article

APA
Crabtree NE, Epstein KL. (2021). Current Concepts in Fluid Therapy in Horses. Front Vet Sci, 8, 648774. https://doi.org/10.3389/fvets.2021.648774

Publication

Frontiers in veterinary science
ISSN: 2297-1769
NlmUniqueID: 101666658
Country: Switzerland
Language: English
Volume: 8
Pages: 648774
PII: 648774

Researcher Affiliations

Crabtree, Naomi E
  • Department of Large Animal Medicine, University of Georgia College of Veterinary Medicine, Athens, GA, United States.
Epstein, Kira L
  • Department of Large Animal Medicine, University of Georgia College of Veterinary Medicine, Athens, GA, United States.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Citations

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