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Cutaneous onchocerciasis in the horse: five cases in southwestern british columbia.

Abstract: Five horses were presented because of a dermatitis of the forehead. Unlike previous reports, ventral midline dermatitis was not the major problem, and was present in only two of five cases. All five horses responded to levamisole therapy at a daily dosage of 5.5 g for one week. Owners were cautioned that repeat therapy may be necessary.
Publication Date: 1983-01-01 PubMed ID: 17422217PubMed Central: PMC1790237
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  • Journal Article

Summary

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The objective of the research was to explore the occurrence and treatment of cutaneous onchocerciasis, a skin condition, in horses in southwestern British Columbia. Five horses were examined and treated using levamisole therapy, with successful results indicating repeat therapy may be necessary.

Presentation of Dermatitis in Horses

  • The research involved studying five horses that were brought in due to a dermatitis condition affecting their foreheads. Dermatitis in the forehead of these horses was the central focus, as this presented a contrasting symptomology compared to previous studies where ventral midline dermatitis, a skin inflammation along the belly line, was often reported.
  • Interestingly, only two out of the five horses exhibited the typical ventral midline dermatitis. This observation further challenges the predominance of belly line dermatitis in the horse population, making this research stand out among the previous studies.

Treatment with Levamisole Therapy

  • For the treatment of this dermatitis, all horses were subjected to Levamisole therapy, a type of medication used to treat parasitic worm infections. They were given daily doses of the drug at 5.5 grams for a duration of one week.
  • The successful response to the Levamisole therapy was consistent in all five horses. However, the researchers caution that repeated therapy sessions might be needed. This need for repeat therapy implies that while Levamisole effectively manages the symptoms, it may not necessarily cure the condition.

Implications for Future Studies

  • The findings of this study highlight the evolving nature of skin conditions like cutaneous onchocerciasis in horses. By shedding light on the variations in dermatitis presentation, it is possible to conduct more detailed future investigations to understand the range and mechanism of skin inflammation in horses.
  • The study also brings to the fore the effective role of Levamisole therapy in managing the condition. Further research could explore the frequency and intensity of Levamisole therapy necessary for achieving long-term resolution of the dermatitis in the horse population.

Cite This Article

APA
Lees MJ, Kleider N, Tuddenham TJ. (1983). Cutaneous onchocerciasis in the horse: five cases in southwestern british columbia. Can Vet J, 24(1), 3-5.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 24
Issue: 1
Pages: 3-5

Researcher Affiliations

Lees, M J
    Kleider, N
      Tuddenham, T J

        References

        This article includes 7 references
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        Citations

        This article has been cited 5 times.
        1. Cambra-Pellejà M, Gandasegui J, Balaña-Fouce R, Muñoz J, Martínez-Valladares M. Zoonotic Implications of Onchocerca Species on Human Health. Pathogens 2020 Sep 17;9(9).
          doi: 10.3390/pathogens9090761pubmed: 32957647google scholar: lookup
        2. Lia RP, Mutafchiev Y, Veneziano V, Giannelli A, Abramo F, Santoro M, Latrofa MS, Cantacessi C, Martin C, Otranto D, Bertuglia A, Riccio B. Filarial infection caused by Onchocerca boehmi (Supperer, 1953) in a horse from Italy. Parasitol Res 2017 Jan;116(1):191-198.
          doi: 10.1007/s00436-016-5277-xpubmed: 27761717google scholar: lookup
        3. Anderson GS, Belton P, Kleider N. The hypersensitivity of horses to culicoides bites in british columbia. Can Vet J 1988 Sep;29(9):718-23.
          pubmed: 17423117
        4. Polley L. Onchocerca in horses from Western Canada and the northwestern United States: an abattoir survey of the prevalence of infection. Can Vet J 1984 Mar;25(3):128-9.
          pubmed: 17422371
        5. Kleider N, Lees MJ. Culicoides hypersensitivity in the horse: 15 cases in southwestern british columbia. Can Vet J 1984 Jan;25(1):26-32.
          pubmed: 17422351