D(+)-xylose absorption test in the horse. A clinical study.

The research investigates the effectiveness of the D(+)-xylose absorption test in horses, indicating that the test is significant in assessing intestinal function, especially in horses showing signs of gastrointestinal disease.

Methodology

In this study, D(+)-xylose absorption tests were performed on 25 horses. The test involved administering 1 gram of D(+)-xylose per kilogram of body weight to each horse orally. The absorption of D(+)-xylose was then observed and recorded.

Grouping of the Subjects

Following the D(+)-xylose administration, the horses’ absorption curves were used to categorize them into four distinct groups:

• Group 1 comprised 11 horses that exhibited a normal absorption curve.
• Group 2 included 5 horses with a flat absorption curve.
• Group 3 constituted another 3 horses also with a flat absorption curve.
• Group 4 contained 7 horses characterized by an intermediary type of absorption curve.

Further Investigation

In an effort to understand the effects of other substances on D(+)-xylose absorption, sodium chloride was administered in equimolar concentrations to the horses. According to the research, this did not significantly improve the absorption of D(+)-xylose.

Test Results and Conclusion

Interestingly, 73 per cent of the horses displaying current or recent signs of gastrointestinal disease demonstrated decreased D(+)-xylose absorption. These findings consequently suggest that the D(+)-xylose absorption test is a beneficial diagnostic tool for evaluating intestinal function in horses, particularly those with gastrointestinal diseases. It is important to note, however, that further comprehensive studies may be necessary to confirm these results and explore potential improvements to this testing method.