FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Vet Sci / Dentigerous Equine Teratoma in a Stallion: Surgical Manageme...
Veterinary sciences2021; 8(5); doi: 10.3390/vetsci8050084

Dentigerous Equine Teratoma in a Stallion: Surgical Management and Clinicopathology.

Abstract: Teratoma is a rare germ cell testicular cancer composed of cells that are not normally present in the site where it originates. These tumors are rarely described in horses, where they may develop due to cryptorchidism. Teratomas consist of cells originating from different germinal layers, arising from germinal multi-potential cells with differentiation defects, and can simultaneously contain several tissues from two or more embryonic layers. Testicular teratomas are described in horses, cats, dogs, wild boars, bulls, and humans. In the rare descriptions found in literature of testicular teratoma in stallions, they occur frequently in cryptorchid testicles, as a consequence of congenital neoplasm. To our knowledge there is no other report of a dentigerous equine teratoma in a stallion. We describe here a successful laparoscopic removal of a testicular teratoma and its clinic-pathological features.
Get Full Text
Publication Date: 2021-05-13 PubMed ID: 34068130PubMed Central: PMC8152738DOI: 10.3390/vetsci8050084Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Case Reports
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study discusses a rare germ cell cancer known as teratoma in horses. The researchers report a unique case of a dentigerous equine teratoma in a stallion, which was successfully removed using laparoscopic surgery.

Understanding Teratoma

  • Teratoma is a type of cancer that originates from cells not normally found in the location where the tumor develops.
  • This cancer usually stems from multiple potential germ cells that have differentiation defects, meaning the cells develop into types they normally wouldn’t.
  • Resembling an abnormal organ or tissue, a teratoma can contain multiple cell types from two or more embryonic layers.
  • Teratomas are rarely seen in horses but have been described in different animals including cats, dogs, wild boars, bulls, and even humans.

Equine Teratomas and Cryptorchidism

  • In horses, teratomas may develop due to a condition called cryptorchidism, where one or both of the testes fail to descend.
  • The study highlights that among the few cases of testicular teratomas in stallions reported in literature, most occurred in cryptorchid testicles.
  • This suggests a link between undescended testicles and the development of teratomas, potentially as a result of a congenital neoplasm, or a new, abnormal growth that usually refers to a cancer.

Dentigerous Equine Teratoma Case

  • This case study reports the first known case of a dentigerous equine teratoma in a stallion. Dentigerous refers to the presence of teeth, indicating that this teratoma contained tooth-like structures.
  • The tumor was successfully removed using laparoscopic surgery, a minimally invasive surgical technique that allows for a quicker recovery and less post-operative discomfort.
  • Clinico-pathological features of the teratoma were also provided, but the abstract doesn’t give explicit details. These features would generally include the appearance, size, and structure of the tumor, along with the horse’s symptoms and prognosis after removal.

Cite This Article

APA
Leonardi L, Bertoletti A, Bellezza E, Pettinari I, Gialletti R. (2021). Dentigerous Equine Teratoma in a Stallion: Surgical Management and Clinicopathology. Vet Sci, 8(5). https://doi.org/10.3390/vetsci8050084

Publication

Veterinary sciences
ISSN: 2306-7381
NlmUniqueID: 101680127
Country: Switzerland
Language: English
Volume: 8
Issue: 5

Researcher Affiliations

Leonardi, Leonardo
  • Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4-06126 Perugia, Italy.
Bertoletti, Alice
  • Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4-06126 Perugia, Italy.
Bellezza, Enrico
  • Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4-06126 Perugia, Italy.
Pettinari, Ilaria
  • Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4-06126 Perugia, Italy.
Gialletti, Rodolfo
  • Department of Veterinary Medicine, University of Perugia, Via San Costanzo, 4-06126 Perugia, Italy.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

This article includes 20 references
  1. Ramkumar J, Best A, Gurung A, Dufresne AM, Melich G, Vikis E, MacKenzie S. Resection of ruptured hepatic tera-toma in an adult.. Int. J. Surg. Case Rep. 2018;53:414–419.
    doi: 10.1016/j.ijscr.2018.11.032pmc: PMC6259038pubmed: 30567058google scholar: lookup
  2. Ashley DJB. Origin of teratomas.. Cancer 1973;32:390–394.
    doi: 10.1002/1097-0142(197308)32:2<390::AID-CNCR2820320216>3.0.CO;2-Wpubmed: 4722920google scholar: lookup
  3. AlQurashi A, Bakry E, Straube M, Rickert CH, Mir-Salim P. Mature Teratoma of the Temporal Bone in 3.5-Month-Old Baby Girl.. Case Rep. Otolaryngol. 2015;2015:372089.
    doi: 10.1155/2015/372089pmc: PMC4402470pubmed: 25945275google scholar: lookup
  4. Lefebvre R, Theoret C, Doré M, Girard C, Laverty S, Vaillancourt D. Ovarian teratoma and endometritis in a mare.. Can. Veter. J. La Rev. Veter. Can. 2005;46:1029–1033.
    pmc: PMC1259148pubmed: 16363331
  5. Maghrabi Y, Kurdi ME, Baeesa SS. Infratentorial immature teratoma of congenital origin can be associated with a 20-year survival outcome: A case report and review of literature.. World J. Surg. Oncol. 2019;17:22.
    doi: 10.1186/s12957-019-1564-1pmc: PMC6339688pubmed: 30660187google scholar: lookup
  6. Ting J, Bell D, Ahmed S, Ying A, Waguespack SG, Tu SM, Weber R, Zafereo M. Primary Malignant Thyroid Teratoma: An Institutional Experience.. Thyroid 2019;29:229–236.
    doi: 10.1089/thy.2018.0206pubmed: 30759052google scholar: lookup
  7. Cribb NC, Bourã LP, Bouré LP. Laparoscopic Removal of a Large Abdominal Testicular Teratoma in a Standing Horse.. Veter. Surg. 2010;39:131–135.
    doi: 10.1111/j.1532-950X.2009.00618.xpubmed: 20210958google scholar: lookup
  8. Meliti A, Hafiz B, Al-Maghrabi H, Gari A. Collision Glial Neoplasms Arising in an Ovarian Mature Cystic Teratoma: A Rare Event.. Case Rep. Pathol. 2020;2020:7568671–7568674.
    doi: 10.1155/2020/7568671pmc: PMC7021464pubmed: 32082676google scholar: lookup
  9. Fox L, Hanley CS, Padilla LR, Duncan M. Bladder teratoma in a maned wolf (Chrysocyon brachyurus). Open Veter. J. 2019;9:259–262.
    doi: 10.4314/ovj.v9i3.11pmc: PMC6794395pubmed: 31998620google scholar: lookup
  10. Meuten DJ. Tumors in Domestic Animals.. 5th ed. 1606 Golden Aspen Drive, Suites 103 and 104; Ames, IA, USA: 2017. Tumors of the Genital System (Testicle) pp. 706–721.
  11. Kumar V, Abbas AK, Aster JC. Robbins—Fondamenti di Patologia e di Fisiopatologia.. 9th ed. Edra Masson LSWR Srl; Milano, Italy: 2013. p. 646.
  12. Ugolini LW, Cunha dos Santos FC, da Costa GV, Oliveira HR, Folchini N, Machad TP, Zannella R, Porto Alves L. Testicular Teratoma in a Unilateral RightSided Abdominal Cryptorchid Horse.. Acta Sci. Vet. 2019;47:409.
  13. Ulbright TM. Germ cell tumors of the gonads: A selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.. Mod. Pathol. 2005;18:S61–S79.
    doi: 10.1038/modpathol.3800310pubmed: 15761467google scholar: lookup
  14. Nielsen SW, Misdorp W, Mcentee K. Tumours of the ovary.. Bull. World Health Organ. 1976;53:203–215.
    pmc: PMC2366495pubmed: 1086151
  15. Pasolini MP, Della Valle G, Pagano TB, Miele F, Paciello O, Fatone G, Greco M. Mature teratoma arising from an un-descended testis in a horse: Comparison between ultrasonographic and morphological features.. Folia Morphol. 2016;75:211–215.
    doi: 10.5603/FM.a2015.0088pubmed: 26431049google scholar: lookup
  16. Smyth GB. Testicular Teratoma in an Equine Cryptorchid.. Equine Veter. J. 1979;11:21–23.
    doi: 10.1111/j.2042-3306.1979.tb01288.xpubmed: 34510google scholar: lookup
  17. Chowdhury W, Lodhi MU, Syed IA, Rahim U, Rahim M. Mature Testicular Teratoma with a Focus of Embryonal Car-cinoma: A Case Report and Review of Literature.. Cureus 2018;10:e2329.
    pmc: PMC5953511pubmed: 29770282
  18. Baidya KP, Ghosh S, Datta A, Mukhopadhyay S, Bhaduri G. Huge congenital teratoma containing tooth in a three-day-old neonate.. Oman J. Ophthalmol. 2014;7:13–15.
    doi: 10.4103/0974-620X.127912pmc: PMC4008892pubmed: 24799795google scholar: lookup
  19. Bouzoubaa W, Jayi S, Alaoui FZF, Chaara H, Melhouf MA. Tératome immature de l’ovaire: À propos d’un cas [Imma-ture teratoma of the ovary: About a case.. Pan. Afr. Med. J. 2017;27:263.
    doi: 10.11604/pamj.2017.27.263.6400pmc: PMC5660326pubmed: 29187932google scholar: lookup
  20. Hendrickson D. Laparoscopic Cryptorchidectomy and Ovariectomy in Horses.. Veter. Clin. N. Am. Equine Pr. 2006;22:777–798.
    doi: 10.1016/j.cveq.2006.08.006pubmed: 17129803google scholar: lookup
Subscribe to our newsletter
Join 99,344 horse owners like you who receive our email updates on horse health and nutrition.