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Veterinary ophthalmology2014; 18(5); 357-363; doi: 10.1111/vop.12199

Descemet’s membrane detachment in horses; case series and literature review.

Abstract: The aim of this article was to describe Descemet's membrane detachment (DMD) following phacoemulsification in five equine eyes and to review the human literature on this topic. In the last decade, there has been increased reporting of DMD in the human literature, in particular following cataract surgery. The natural history of DMD remains unknown and although various medical and surgical treatments have been advocated there is no recognized 'gold standard' treatment for DMD. This case series reports the diagnosis of DMD in four horses (5 eyes) in association with phacoemulsification surgery. The diagnosis of DMD in these patients was made intra-operatively, postoperatively or on subsequent histopathological examination. The surgical reports, photographic or video recordings, and ultrasound data were evaluated and possible factors associated with the pathophysiology of DMD are discussed. This is the first description of DMD in the veterinary literature, and the authors believe that DMD might hitherto have been overlooked in veterinary ophthalmology due to a lack of awareness of the condition. The possible causes, clinical signs, and treatment of DMD as described in the human literature are also reviewed.
Publication Date: 2014-09-02 PubMed ID: 25180582DOI: 10.1111/vop.12199Google Scholar: Lookup
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Summary

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This research involves a study of Descemet’s membrane detachment (DMD) in horses following phacoemulsification and includes a review of human literature on the issue.

Understanding the Research

The primary aim of this study was to explain instances of Descemet’s membrane detachment (DMD) after phacoemulsification in equine eyes.

  • Phacoemulsification is a modern cataract surgery technique, using sound waves to break up and remove the lens in the eye, which has become opaque due to a cataract.
  • Descemet’s membrane is a thin, protective layer that makes up the innermost lining of the cornea (the clear, front part of the eye).
  • Descemet’s membrane detachment (DMD) is a rare but serious complication that can occur following cataract surgery. This detachment can lead to corneal edema (swelling) and potentially, loss of vision.

Methodology and Findings

The report details the diagnosis of DMD in four horses, affecting five eyes total, after these subjects underwent phacoemulsification. The diagnosis was made at varying stages – during the procedure, afterwards, or after a histopathological examination.

  • The investigative team analyzed surgical reports, photographic or video documentation, and ultrasound data collected throughout the process.
  • This offered them means to consider possible pathology factors and offer relevant commentary.

DMD in the Veterinary Context

This recorded study of DMD is the first of its kind to appear in veterinary literature.

  • The authors speculate that DMD might have been previously undiscovered within the realm of veterinary ophthalmology due to insufficient knowledge of the condition.
  • Before this research, there was no ‘gold standard’ treatment – or definitive solution – for DMD, largely due to its uncertain natural history or progression.
  • The researchers also reviewed potential causes, signs, and treatments of DMD as highlighted in human literature.

In conclusion, the research has provided veterinary science with much-needed insight about DMD occurrences in equine subjects, thereby paving the way for better diagnosis and potential treatments for this condition in the future.

Cite This Article

APA
Matas Riera M, Donaldson D, Priestnall SL. (2014). Descemet’s membrane detachment in horses; case series and literature review. Vet Ophthalmol, 18(5), 357-363. https://doi.org/10.1111/vop.12199

Publication

ISSN: 1463-5224
NlmUniqueID: 100887377
Country: England
Language: English
Volume: 18
Issue: 5
Pages: 357-363

Researcher Affiliations

Matas Riera, Màrian
  • Ophthalmology Service, Royal Veterinary College, Hawkshead Lane North Mymms, AL97TA London, UK.
Donaldson, David
  • Unit of Comparative Ophthalmology, Animal Health Trust, Lanwades Park, Newmarket CB87UU, UK.
Priestnall, Simon Lawrence
  • Dept of Pathology and Pathogen Biology, Royal Veterinary College, Hawkshead Lane, North Mymms, AL97TA London, UK.

MeSH Terms

  • Animals
  • Cataract / veterinary
  • Corneal Diseases / diagnosis
  • Corneal Diseases / etiology
  • Corneal Diseases / pathology
  • Corneal Diseases / veterinary
  • Descemet Membrane / pathology
  • Female
  • Horse Diseases / etiology
  • Horse Diseases / pathology
  • Horse Diseases / surgery
  • Horses / surgery
  • Humans
  • Male
  • Phacoemulsification / adverse effects

Citations

This article has been cited 1 times.
  1. Slenter IJM, Hermans H, Ensink JM, Willems DS, Veraa S, Grinwis GCM, Boevé MH. Clinical, ultrasonographic, and histopathologic findings in seven horses with Descemet's membrane detachment: A case series. Vet Ophthalmol 2020 Jan;23(1):181-189.
    doi: 10.1111/vop.12710pubmed: 31544302google scholar: lookup