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Theriogenology2020; 156; 196-204; doi: 10.1016/j.theriogenology.2020.07.009

Doppler indices of the equine fetal carotid artery throughout gestation.

Abstract: Assessment of pregnancy viability in the equine patient is currently based on gestational profiles of limited prognostic value. In recent years Doppler technology has been applied to uterine and umbilical arteries of pregnant mares to monitor fetal responsive haemodynamics, suggestive of compromise. To date, uterine artery Doppler indices failed to provide sufficient evidence of pregnancy viability and the umbilical cord of the equine fetus is inconsistently visualized past 250 days gestation. The objectives of this study were to: i) evaluate intracranial blood flow impedance by Doppler examination of the fetal carotid artery and ii) establish reference values for healthy, uncomplicated pregnancies. The middle cerebral artery (MCA), a branch of the carotid artery, is commonly employed to assess intracranial hemodynamics in the human fetus, exhibiting high resistance to circulation to the fetal brain in uncomplicated pregnancies. For the purpose of this study, 12 pregnant mares were examined at 2-3 weeks interval by B mode and Doppler ultrasonography until delivery and a novel technique was developed for Doppler evaluation of the carotid artery in the equine fetus, in order to provide objective evidence of the hemodynamic status of the equine fetus. Additional biophysical and biochemical parameters were collected to demonstrate appropriate pregnancy development. In this study Doppler waveform analysis of fetal intracranial vasculature demonstrated an elevated blood flow impedance, showing a significant correlation of carotid Doppler indices with gestational age. Results were comparable to human fetal trends for the middle cerebral artery (MCA) from mid gestation to term. Biochemical data showed expected patterns of uncomplicated pregnancies.
Publication Date: 2020-07-12 PubMed ID: 32755719DOI: 10.1016/j.theriogenology.2020.07.009Google Scholar: Lookup
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  • Journal Article

Summary

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The research article discusses how Doppler technology can be used to monitor horse pregnancies by evaluating intracranial blood flow in the fetal carotid artery. It works towards establishing standard values for healthy pregnancies, and reveals significant correlation between carotid Doppler indices and gestational age.

Understanding the Purpose of the Research

  • The study aimed to improve existing methods of assessing pregnancy health in horses, which is currently based on gestational profiles that offer limited prognostic value.
  • The researchers aimed to evaluate the intracranial blood flow resistance of a horse fetus using Doppler technology to inspect the fetal carotid artery.
  • The purpose was also to set reference values for healthy and uncomplicated pregnancies in horses.

Methodology

  • Twelve pregnant mares were examined over the course of their gestation periods, with checks happening every 2-3 weeks until delivery.
  • B mode and Doppler ultrasonography were used as non-invasive techniques for these checks. A new method was developed for the Doppler evaluation of the carotid artery in the fetal horses, providing objective evidence of their hemodynamic status.
  • Other biophysical and biochemical parameters were also collected during the study to ensure the development of the pregnancies were proceeding as expected.

Findings and Conclusions

  • The use of Doppler waveform analysis showed an elevation in blood flow impedance in the fetal intracranial vasculature. This showed a strong correlation with gestational age, suggesting it could be a valuable tool for tracking pregnancy health.
  • The patterns observed in the data were comparable to human fetal trends for the middle cerebral artery (MCA) from mid gestation through to term, adding further credibility to the new method.
  • Other biochemical data collected supported the expected patterns of uncomplicated pregnancies in horses.

Ultimately, this study demonstrated that Doppler technology, specifically the application of Doppler waveform analysis of the fetal carotid artery, could be an effective tool for monitoring the health of fetal horses throughout gestation. The data suggests it could provide a reliable method of prognosis and ongoing assessment throughout a mare’s pregnancy.

Cite This Article

APA
Bucca S, De Oliveira IRS, Cunanan JC, Vinardell T, Troedsson MHT. (2020). Doppler indices of the equine fetal carotid artery throughout gestation. Theriogenology, 156, 196-204. https://doi.org/10.1016/j.theriogenology.2020.07.009

Publication

ISSN: 1879-3231
NlmUniqueID: 0421510
Country: United States
Language: English
Volume: 156
Pages: 196-204

Researcher Affiliations

Bucca, Stefania
  • Equine Veterinary Medical Center, Qatar Foundation, Doha, Qatar. Electronic address: stefbucca@gmail.com.
De Oliveira, Isabelle R Sousa
  • Al Shaqab, Qatar Foundation, Doha, Qatar.
Cunanan, Janinne C
  • Equine Veterinary Medical Center, Qatar Foundation, Doha, Qatar.
Vinardell, Tatiana
  • Equine Veterinary Medical Center, Qatar Foundation, Doha, Qatar; College of Health & Life Science, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar.
Troedsson, Mats H T
  • Maxwell H.Gluck Equine Research Center, University of Kentucky, Lexington, KY, 40546, USA.

MeSH Terms

  • Animals
  • Blood Flow Velocity
  • Carotid Arteries
  • Female
  • Fetus
  • Gestational Age
  • Horses
  • Humans
  • Pregnancy
  • Ultrasonography, Doppler / veterinary
  • Ultrasonography, Prenatal / veterinary
  • Umbilical Arteries / diagnostic imaging

Conflict of Interest Statement

Declaration of competing interest No disclosures nor conflicts of interest pertain to the authors of this study.

Citations

This article has been cited 2 times.
  1. Ali A, Derar DR, Alaeyeari AA, Alharbi YM. Fetometry in Arabian horses. Front Vet Sci 2025;12:1689769.
    doi: 10.3389/fvets.2025.1689769pubmed: 41209474google scholar: lookup
  2. Poradowski D, Chrószcz A. Equine Stomach Development in the Fetal Period: An Anatomical, Topographical, and Morphometric Study. Animals (Basel) 2022 Oct 28;12(21).
    doi: 10.3390/ani12212966pubmed: 36359095google scholar: lookup