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Home / Equine Research Bank / J Vet Intern Med / Effect of diet composition on glandular gastric disease in h...
Journal of veterinary internal medicine2023; 37(4); 1528-1536; doi: 10.1111/jvim.16747

Effect of diet composition on glandular gastric disease in horses.

Abstract: Nutritional factors are suggested to influence the incidence and severity of glandular gastric disease (GGD) in horses. Objective: To retrospectively assess whether dietary fermentable carbohydrates increase the severity of GGD and to prospectively evaluate whether the partial substitution of concentrates by dehydrated alfalfa would decrease GGD severity scores. Methods: In total, 82 trotters from 4 training centers exercised ≥5 days/week. Methods: Multicenter retrospective observational study, and prospective 2-arm randomized trial. Glandular mucosae were observed by gastroscopy and scored (0-4 severity scale) at day 0 (D0). Biochemical composition of the diet fed was compared between ulcerated and nonulcerated groups. After D0, horses either received the same diet (control, n = 41) or pelleted dehydrated alfalfa substituting 50% concentrates (alfalfa, n = 41). Glandular scores were recorded in both groups after 21 (D21) and 42 days (D42). The first end point was a successful outcome, defined as a horse with a glandular score of 2 to 4 on D0, decreasing to a score of 0 to 1 on days 21 or 42. Results: Horses scored 0 to 1 at D0 ingested more (P = .01) soluble sugars from concentrates than those scored 2 to 4 before D0 (77.5 g/kg BW; 95% confidence interval [CI]: 71.1-84.0, vs 59.1 g/kg BW; 95% CI: 48.0-70.3), whereas starch intake did not differ between groups (P = .24). Among horses scored 2 to 4 at D0, fewer were scored 2 to 4 in the alfalfa group (1 out of 6) compared with the control group (6 out of 6) at D42 (P = .02). Clinical success was 47.7 times more likely in horses fed alfalfa compared with horses in the control group (95% CI: 1.6-1422.8). Conclusions: Relationships were found between diet composition and integrity of the glandular mucosa. Feeding pelleted dehydrated alfalfa could help to reduce the incidence and severity of GGD.
© 2023 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC. on behalf of the American College of Veterinary Internal Medicine.
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Publication Date: 2023-06-01 PubMed ID: 37264707PubMed Central: PMC10365063DOI: 10.1111/jvim.16747Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research investigated the impact of diet on the development of glandular gastric disease (GGD) in horses. It found out that horses fed with a diet partly consisting of dehydrated alfalfa showed a significant reduction in the severity of GGD.

Objective and Methodology of the Study

  • The main objective of the study was to understand whether dietary fermentable carbohydrates increase the severity of GGD, and to evaluate if substituting concentrates with dehydrated alfalfa could potentially reduce GGD severity.
  • The participants of the study were 82 trotters from 4 training centers, who exercised at least 5 days a week.
  • The research was conducted as a multicenter retrospective observational study, and a prospective two-arm randomized trial.
  • To measure the severity of GGD, the glandular mucosa of the horses were observed via gastroscopy and scored on a 0-4 severity scale, at the commencement of the study.
  • The biochemical composition of the diet given to ulcerated and non-ulcerated groups was then compared.
  • After the start of the study, one group of horses (control group) continued on their original diet , while for the other group (alfalfa group) 50% of their concentrates were substituted with pelleted dehydrated alfalfa.
  • After 21 days (D21) and 42 days (D42) the glandular scores were recorded again.

Results of the Study

  • It was found that horses who had a lower GGD score ingested more soluble sugars from concentrates than those with a higher score.
  • Starch intake did not show any significant difference between the groups with different scores.
  • Among the horses which had a score of 2 to 4 at the start of the study, fewer horses had a similar score in the alfalfa group as compared to control group, by D42. Hence, a successful outcome of reducing the severity of GGD was 47.7 times more likely in the horses that were fed alfalfa.

Conclusion of the Study

  • The study concluded that diet composition significantly affects the integrity of the glandular mucosa in horses.
  • Also, feeding horses with pelleted dehydrated alfalfa could significantly reduce the incidence and severity of GGD.

Cite This Article

APA
Julliand S, Buttet M, Hermange T, Hillon P, Julliand V. (2023). Effect of diet composition on glandular gastric disease in horses. J Vet Intern Med, 37(4), 1528-1536. https://doi.org/10.1111/jvim.16747

Publication

Journal of veterinary internal medicine
ISSN: 1939-1676
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 37
Issue: 4
Pages: 1528-1536

Researcher Affiliations

Julliand, Samy
  • UMR PAM A 02.102, Dijon, France.
  • Lab To Field, Dijon, France.
Buttet, Marjorie
  • Lab To Field, Dijon, France.
Hermange, Tanguy
  • Centre Hospitalier Vétérinaire Equin de Livet, Livarot-Pays-d'Auge, France.
Hillon, Patrick
  • University of Bourgogne-Franche Comté, Dijon, France.
  • INSERM U1231, Lipids, Nutrition, Cancer, Dijon, France.
  • Department of Hepatogastroenterology, University Hospital, Dijon, France.
Julliand, Véronique
  • UMR PAM A 02.102, Dijon, France.
  • University of Bourgogne-Franche Comté, Dijon, France.
  • Agrosup Dijon, Dijon, France.

Grant Funding

  • CASDAR (French Ministry of Agriculture and Food)

Conflict of Interest Statement

Authors declare no conflict of interest.

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