Effect of orally administered sodium bicarbonate on caecal pH.
Abstract: Caecal acidosis is a central event in the metabolic cascade that occurs following grain overload. Buffering the caecal acidosis by enterally administered sodium bicarbonate (NaHCO3 ) may be beneficial to affected horses. Objective: To determine the effect and duration of enterally administered NaHCO3 on caecal pH in healthy horses. Methods: Experimental study using horses with caecal cannulas. Methods: Nine horses had been previously fitted with a caecal cannula. Six horses received 1.0 g/kg bwt NaHCO3 and 3 control horses were given 3 l of water via nasogastric tube. Clinical parameters, water consumption, venous blood gases, caecal pH, faecal pH and faecal water content were measured at 6 h intervals over a 36 h study period. Results: Horses that received enterally administered NaHCO3 had significantly increased caecal pH that lasted the duration of the study. Treated horses increased their water intake, and developed metabolic alkalaemia, significantly increased plasma sodium concentrations and significantly decreased plasma potassium concentrations. Conclusions: Enterally administered NaHCO3 may be beneficial in buffering caecal acidosis.
© 2013 EVJ Ltd.
Publication Date: 2013-08-30 PubMed ID: 23738517DOI: 10.1111/evj.12111Google Scholar: Lookup
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- Journal Article
- Randomized Controlled Trial
- Research Support
- Non-U.S. Gov't
Summary
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The research investigates the impact and longevity of orally given sodium bicarbonate (NaHCO3) on the pH level in a horse’s caecum. The results demonstrate that horses treated with oral sodium bicarbonate had a significantly higher caecal pH for the length of the study.
Methods
- The study was experimental and involved horses with caecal cannulas. The caecum in horses is an organ that aids in the digestion of fibrous material. It also maintains a balance in acidity level, which could get disrupted during grain overload leading to caecal acidosis.
- Out of nine horses, six were given 1.0 g/kg bwt NaHCO3, while the remaining three control horses were given 3 l of water through a nasogastric tube.
- The team recorded clinical parameters, water intake, venous blood gases, caecal pH, fecal pH, and fecal water content. These measurements were taken every 6 hours over a 36-hour period.
Results
- Horses that were given NaHCO3 orally had a significant increase in caecal pH that lasted throughout the study period.
- Treated horses also increased their water consumption, experienced metabolic alkalaemia, showed a significant rise in plasma sodium concentrations, and a significant decrease in plasma potassium concentrations. Metabolic alkalaemia occurs when there are fewer hydrogen ions in the blood, resulting in a higher pH level, making the blood more alkaline.
Conclusions
- The researchers concluded that the oral administration of NaHCO3 could potentially be helpful in buffering caecal acidosis.
Implications of the research
- This study will help to educate veterinarians and horse caretakers about the possible benefits of oral sodium bicarbonate in cases of potential grain overload and caecal acidosis.
- However, as the study is experimental and conducted on a small scale, further research with larger sample sizes may be needed to solidify the findings and understand any potential side-effects.
Cite This Article
APA
Taylor EA, Beard WL, Douthit T, Pohlman L.
(2013).
Effect of orally administered sodium bicarbonate on caecal pH.
Equine Vet J, 46(2), 223-226.
https://doi.org/10.1111/evj.12111 Publication
Researcher Affiliations
- Department of Clinical Sciences, Kansas State University, USA.
MeSH Terms
- Administration, Oral
- Animals
- Cecum / drug effects
- Cecum / physiology
- Feces / chemistry
- Female
- Horses
- Hydrogen-Ion Concentration
- Male
- Sodium Bicarbonate / administration & dosage
- Sodium Bicarbonate / pharmacology
Citations
This article has been cited 1 times.- Arroyo LG, Costa MC, Guest BB, Plattner BL, Lillie BN, Weese JS. Duodenitis-Proximal Jejunitis in Horses After Experimental Administration of Clostridium difficile Toxins. J Vet Intern Med 2017 Jan;31(1):158-163.
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