Effect of the Interval From Prostaglandin F2alpha Treatment to Ovulation on Reproductive Efficiency Rates in a Commercial Equine Embryo Transfer Program.
Abstract: In the present study, 2.228 cycles of 180 Polo Argentino donor mares from an embryo transfer program in Argentina were examined to evaluate the effects of: (1) Interval from Prostaglandin F2alpha analog treatment to ovulation (ITO) on embryo recovery rate (ERR); (2) ITO on number of embryos per flushing (EPF); (3) ITO on multiple ovulation (MO) rate; (4) ITO from donor mare on pregnancy rate (PR) in recipient mares. Mares were inseminated with fresh semen from 31 fertile stallions in the induced estrus. Embryo flushing was performed 7-8 days postovulation. Following embryo flushing, donor mares were treated with prostaglandin F2alpha analog (cloprostenol 250 μg). The ERR increased along with the ITO (P = .01), with the lowest ERR (30.7%) for mares with an ITO of <4 days, and the highest (78.3%) in mares with an ITO of 10 days. The ITO from the donor mare in which the embryo was recovered did not have a significant effect on PR: ITO <6, 6 to 10, and >10 days were 74.6, 81.4, and 77.3%, respectively. The number of EPF and MO rate increased gradually along with the ITO (P < .05). In conclusion, the results of this study indicated that the ITO is positively correlated with the embryo recovery and the multiple ovulation rate.
Copyright © 2019 Elsevier Inc. All rights reserved.
Publication Date: 2019-04-25 PubMed ID: 31203975DOI: 10.1016/j.jevs.2019.04.006Google Scholar: Lookup
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Summary
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The research paper explores the influence of the interval between treatments of Prostaglandin F2alpha analog and ovulation on the reproductive success rates in a commercial equine embryo transfer program involving 180 Polo Argentino donor mares. The key variables monitored include embryo recovery rate, number of embryos per flushing, multiple ovulation rate, and pregnancy rate.
Study Methodology
- The researchers examined 2,228 cycles of 180 Polo Argentino donor mares from an embryo transfer program in Argentina.
- The mares were inseminated with fresh semen from 31 fertile stallions during induced estrus.
- Following ovulation, embryo flushing was performed 7-8 days postovulation.
- After flushing, the mares were treated with a Prostaglandin F2alpha analog, cloprostenol. The timing of this treatment in relation to ovulation, known as the Interval to Ovulation (ITO), was the primary variable under investigation.
Findings
- Embryo Recovery Rate (ERR): ERR rose in conjunction with ITO (P= .01), hitting the lowest rate (30.7%) for mares with an ITO below 4 days, peaking (78.3%) for mares with an ITO of 10 days.
- Impact on Pregnancy Rate: Despite the demonstrated impact of ITO on ERR, ITO did not show a significant effect on Pregnancy Rate (PR) across the tested ranges, with rates hovering around 75-81% regardless of ITO duration.
- Embryos Per Flushing (EPF) and Multiple Ovulation (MO) Rate: A notable increase was observed in both EPF and MO rate as ITO lengthened (P < .05).
Conclusion
- The study concludes that the interval from Prostaglandin F2alpha analog treatment to ovulation (ITO) has a direct, positive correlation with both the embryo recovery and the multiple ovulation rate in Polo Argentino donor mares.
- These findings may have significant implications for the planning and expectations of commercial equine embryo transfer programs, suggesting that longer ITO could increase the chances of embryo recovery and consequently improve the efficiency of such programs.
Cite This Article
APA
Pietrani M, Losinno L, Cuervo Arango J.
(2019).
Effect of the Interval From Prostaglandin F2alpha Treatment to Ovulation on Reproductive Efficiency Rates in a Commercial Equine Embryo Transfer Program.
J Equine Vet Sci, 78, 123-126.
https://doi.org/10.1016/j.jevs.2019.04.006 Publication
Researcher Affiliations
- Cátedra de producción Equina, Universidad Nacional de La Rioja, Argentina, Chamical, La Rioja. Electronic address: melinapietrani@gmail.com.
- Laboratorio de Producción Equina, Facultad de Agronomía y Veterinaria, Universidad Nacional de Rio Cuarto, Río Cuarto, Córdoba, Argentina.
- Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
MeSH Terms
- Animals
- Argentina
- Dinoprost
- Embryo Transfer / veterinary
- Female
- Horses
- Male
- Ovulation
- Pregnancy
- Reproduction
Citations
This article has been cited 2 times.- Dogani M, Askari N, Hesari AK. A diet enriched with Pistacia atlantica fruits improves the female rats' reproductive system. J Tradit Complement Med 2024 May;14(3):335-342.
- Mahmood K, Ali Channa A, Ghafoor A, Riaz A. Factors affecting the efficiency of equine embryo transfer (EET) in polo mares under subtropical conditions of Pakistan. PLoS One 2024;19(2):e0298066.
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