Effects of flunixin on movement and performance of standardbred trotters on the track.
Abstract: An often discussed and controversial issue is the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on performance. The purpose of this study was to investigate the effect of the NSAID flunixin on the movement pattern and performance capacity of Standardbred trotters using a standardised track model. Five adult Standardbred horses in training trotted at 2 occasions with a 2 week interval on the same oval dirt track. Before each occasion the horses were either injected with flunixin meglumine (Finadyne) or normal saline solution i.m. 4 h before the performance test (double blind crossover study). The kinematics for 5 consecutive strides were filmed. There was no significant difference in maximal speed between the saline and flunixin treatment sessions. Significant changes in the movement pattern were observed as an effect of the flunixin treatment. The horses maintained the same stride duration while significantly decreasing stance time and increasing swing time in the forelimbs. The horses' range of limb angle decreased significantly. Heart rates were monitored and plasma lactate and flunixin concentrations were measured. No significant differences were found in heart rate and plasma lactate. The results indicate that flunixin had a significant effect on locomotor pattern while it did not effect metabolic response in these horses (considered to represent a normal race track population). The overall effect on performance in racing horses may therefore be related to the anti-inflammatory and analgesic properties of NSAIDs by masking pain and lameness.
Publication Date: 2000-02-05 PubMed ID: 10659267DOI: 10.1111/j.2042-3306.1999.tb05233.xGoogle Scholar: Lookup
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- Clinical Trial
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This study investigates the impact of the nonsteroidal anti-inflammatory drug flunixin on the movement and performance of Standardbred trotters, finding that while it does not affect maximal speed or metabolic response, it alters the horse’s locomotor pattern.
Methodology
- The researchers used five adult Standardbred horses in training for this study. These horses were made to trot on two separate occasions, two weeks apart, on the same oval dirt track.
- Four hours before each performance test, the horses were injected with either flunixin meglumine (Finadyne) or a normal saline solution. This was done in a double-blind crossover study format, meaning neither the researchers nor the horses’ handlers knew which substance was being administered.
- The kinematics – the study of motion – for five consecutive strides were filmed to record any movement pattern changes.
Key Findings
- Flunixin had no significant impact on the maximum speed of the trotters. Equally, no notable differences were observed in heart rate and plasma lactate levels after flunixin treatment, indicating that the drug did not affect the metabolic response of the horses.
- Notwithstanding, flunixin had a significant impact on the horses’ locomotor pattern. Even though stride duration was maintained, stance time was significantly reduced and swing time in the forelimbs was increased. Additionally, the range of limb angles underwent a significant decrease.
Conclusions and Implications
- The results imply that flunixin, while not altering the horse’s speed or metabolic response, does significantly affect its movement pattern.
- The overall impact on racehorse performance could thus be linked to NSAIDs‘ anti-inflammatory and analgesic properties, which potentially mask pain and lameness.
- This could have implications for the use of NSAIDs in horse racing, as their ability to mask pain could lead to damaging consequences for the horse’s physical welfare if not carefully managed.
Cite This Article
APA
Kallings P, Johnston C, Drevemo S.
(2000).
Effects of flunixin on movement and performance of standardbred trotters on the track.
Equine Vet J Suppl(30), 270-273.
https://doi.org/10.1111/j.2042-3306.1999.tb05233.x Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences, Swedish University of Agricultural Sciences, Faculty of Veterinary Medicine, Uppsala, Sweden.
MeSH Terms
- Animals
- Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
- Clonixin / analogs & derivatives
- Clonixin / therapeutic use
- Cross-Over Studies
- Heart Rate / drug effects
- Horse Diseases / drug therapy
- Horses / physiology
- Lactic Acid / blood
- Lameness, Animal / drug therapy
- Locomotion / drug effects
- Sports
Citations
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