Effects of furosemide on the racing times of horses with exercise-induced pulmonary hemorrhage.
Abstract: In 3 groups of horses with exercise-induced pulmonary hemorrhage (EIPH), comparisons of racing times and finishing positions were made between the 5 races before the horses were given furosemide and 5 races after furosemide administration. The horses were grouped according to 3 methods used to diagnose EIPH: group 1, observation of hemorrhage at the nostrils within 1 hour after a workout or race; group 2, observation of pulmonary hemorrhage only by endoscopic examination after a race or workout; and group 3, observation of hemorrhage at the nostrils during a race or immediately after a race. Group 4 horses were randomly selected horses running during the study period and were not given furosemide. The statistical method was analysis of covariance and the dependent variable was horses' time per distance. The study compared the 4 groups of horses, using the estimated value of the horses (less than or equal to +10,000 or greater than +10,000), and the horses' interaction in races 1 through 5 before and races 6 through 10 after furosemide treatment. The horses' times were adjusted by the relevant covariates, distance, track variant, and winning time per distance. Significant changes in horses' time per distance were not noticed when comparing values from races 1 through 5 with those in races 6 through 10 in group 1 horses.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Date: 1985-04-01 PubMed ID: 4014825
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- Comparative Study
- Journal Article
- Research Support
- Non-U.S. Gov't
- Animal Health
- Clinical Study
- Comparative Study
- Disease Treatment
- Equine Health
- Exercise
- Exercise-Induced Pulmonary Hemorrhage
- Furosemide
- Hemorrhage
- Horse Racing
- Horses
- Observational Study
- Performance Horses
- Pharmacology
- Physiology
- Respiratory Health
- Statistical Analysis
- Thoroughbreds
- Veterinary Medicine
- Veterinary Research
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research explores the impact of furosemide medication on the racing performance of horses suffering from exercise-induced pulmonary hemorrhage (EIPH). No significant change in race times was observed after the treatment.
Objective of the Study
- The study aimed to investigate the impact of furosemide, a diuretic medication, on the racing performance of horses suffering from EIPH, a common medical condition in racehorses characterized by bleeding from the lung area during exercise. The researchers compared race times and finishing positions of horses before and after the administration of the medication.
Study Design and Sample
- The study involved three groups of horses diagnosed with EIPH through varying diagnostic methods: observational hemorrhage at nostrils post-workout or race (group 1), endoscopic examination revelation of hemorrhage (group 2), and nostril hemorrhage during or directly after a race (group 3).
- A fourth group of horses, who were not given furosemide, were also studied during the same period for comparison purposes. These horses were chosen randomly.
Evaluation Methodology
- The researchers used analysis of covariance as the statistical method, having the horses’ time per distance as the dependent variable. They also considered variables such as the horses’ estimated value, race interactions, and other relevant covariates like race distance, track variant, and winning time per distance.
- Findings from each group were compared, specifically races 1 through 5 (before medication) with races 6 through 10 (after medication).
Results of the Study
- The study concluded that the administration of furosemide did not yield any significant improvement to the racing times of the horses, particularly in the case of group 1 horses.
Cite This Article
APA
Soma LR, Laster L, Oppenlander F, Barr-Alderfer V.
(1985).
Effects of furosemide on the racing times of horses with exercise-induced pulmonary hemorrhage.
Am J Vet Res, 46(4), 763-768.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Furosemide / pharmacology
- Furosemide / therapeutic use
- Hemorrhage / drug therapy
- Hemorrhage / physiopathology
- Hemorrhage / veterinary
- Horse Diseases / drug therapy
- Horse Diseases / physiopathology
- Horses
- Lung Diseases / drug therapy
- Lung Diseases / physiopathology
- Lung Diseases / veterinary
- Running
Citations
This article has been cited 1 times.- Hinchcliff KW, Couetil LL, Knight PK, Morley PS, Robinson NE, Sweeney CR, van Erck E. Exercise induced pulmonary hemorrhage in horses: American College of Veterinary Internal Medicine consensus statement. J Vet Intern Med 2015 May-Jun;29(3):743-58.
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