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Home / Equine Research Bank / J Vet Med Sci / Effects of ozonated autohemotherapy on the antioxidant capac...
The Journal of veterinary medical science2015; 77(12); 1647-1650; doi: 10.1292/jvms.15-0225

Effects of ozonated autohemotherapy on the antioxidant capacity of Thoroughbred horses.

Abstract: The performance of horses undergoing regular intense exercise is adversely affected by oxidative stress. Thus, it is important to increase antioxidant production in horses in order to reduce oxidative stress. Ozonated autohemotherapy (OAHT) reportedly promotes antioxidant production. This study aimed to evaluate the effects of OAHT on antioxidant capacity. Ten Thoroughbred horses were used in this study. After the OAHT, we collected serum samples and measured biological antioxidant potential (BAP). We found that BAP began to increase after the OAHT and was significantly higher in the OAHT group than at 3 (P<0.01) and 7 days (P<0.05) after OAHT than in the control group at 3 and 7 days after starting collection of blood samples. Therefore, it was shown that OAHT improved the antioxidant capacity of the horses.
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Publication Date: 2015-07-10 PubMed ID: 26166812PubMed Central: PMC4710722DOI: 10.1292/jvms.15-0225Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research aims to understand the impact of ozonated autohemotherapy (OAHT) on the antioxidant capacity in Thoroughbred horses, with findings suggesting increased antioxidant capacity following OAHT application.

Introduction to the Study

  • The study is centered around the performance of Thoroughbred horses, specifically the factors that can affect this performance negatively. The researchers focused on the concept of oxidative stress, a physiological stress on the body that occurs when there is a lack of antioxidants to prevent the harmful effects of free radicals.
  • As fit horses regularly engaged in intense exercise are susceptible to oxidative stress, the researchers aimed to explore methods to increase antioxidant production in these animals.

Ozonated Autohemotherapy

  • The study employs a method known as Ozonated Autohemotherapy (OAHT). This is a treatment that involves injecting a patient’s blood mixed with ozone back into them, with prior studies suggesting that this therapy promotes antioxidant production.

Methodology and Results

  • In this experiment, ten Thoroughbred horses were used, and serum samples were collected following OAHT.
  • The researchers measured their Biological Antioxidant Potential (BAP), which is a measure of the concentration of antioxidants in the blood.
  • The BAP levels showed an increase after the OAHT treatment. This increase was significantly higher in the OAHT group than the control group at both the 3-day and 7-day marks post receiving OAHT therapy.

Conclusion

  • Based on the observed rise in BAP, the study concluded that Ozonated Autohemotherapy effectively improves the antioxidant capacity in Thoroughbred horses.
  • This suggests potentially beneficial applications for the treatment in improving horse performance by reducing the negative effects of oxidative stress brought about by rigorous exercise.

Cite This Article

APA
Tsuzuki N, Endo Y, Kikkawa L, Korosue K, Kaneko Y, Kitauchi A, Katamoto H, Hidaka Y, Hagio M, Torisu S. (2015). Effects of ozonated autohemotherapy on the antioxidant capacity of Thoroughbred horses. J Vet Med Sci, 77(12), 1647-1650. https://doi.org/10.1292/jvms.15-0225

Publication

The Journal of veterinary medical science
ISSN: 1347-7439
NlmUniqueID: 9105360
Country: Japan
Language: English
Volume: 77
Issue: 12
Pages: 1647-1650

Researcher Affiliations

Tsuzuki, Nao
  • Laboratory of Veterinary Surgery, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Endo, Yoshiro
    Kikkawa, Lisa
      Korosue, Kenji
        Kaneko, Yasuyuki
          Kitauchi, Akira
            Katamoto, Hiromu
              Hidaka, Yuichi
                Hagio, Mitsuyoshi
                  Torisu, Shidow

                    MeSH Terms

                    • Animals
                    • Antioxidants / metabolism
                    • Blood Transfusion, Autologous / veterinary
                    • Horses
                    • Male
                    • Oxidative Stress
                    • Ozone / therapeutic use

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                    Citations

                    This article has been cited 7 times.
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