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Genetika2002; 37(12); 1667-1672;

[Eight polymorphic blood protein systems in Arab horses from Turkey].

Abstract: Analysis of the blood protein system was used to study the genetic composition of Arabian horses. Biochemical markers of eight polymorphic loci (Tf, Al, Es, AlB, Gc, Hb, PGD, and PGM) were electrophoretically identified in blood samples. A total of 43 phenotypes were identified for these polymorphic systems. The Tf, Hb, and Es loci appeared to be more polymorphic than the other loci studied. Statistically significant differences between the observed and expected genotypic frequencies were found for the PGD and PGM loci (P < 0.05 and P < 0.01, respectively). Individual allele frequencies, observed and expected phenotype frequencies, and the average heterozygosity were estimated for each polymorphic locus.
Publication Date: 2002-01-12 PubMed ID: 11785294
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Summary

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This research focusses on a genetic study of Arabian horses in Turkey using analysis of eight polymorphic loci in their blood protein system. The polymorphic nature of these loci helps identify the genetic diversity within this population.

Study Methodology and Results

  • The researchers conducted the study by analyzing the blood protein systems in Arabian horses from Turkey.
  • Eight polymorphic loci were examined, namely, Transferrin (Tf), Alkaline Phosphatase (Al), Esterase (Es), Group-specific Component (Gc), Hemoglobin (Hb), Phosphogluconate Dehydrogenase (PGD) and Phosphoglucomutase (PGM), and AlB (a term that is not specified in the initial abstract). Polymorphic refers to the existence of two or more variants (alleles) at a particular genetic locus within a population.
  • A total of 43 different phenotypes were determined across these polymorphic systems. A phenotype refers to the observable characteristics or traits of an organism that are produced by the interaction of its genotype (set of genes) with the environment.
  • The Tf, Hb, and Es loci displayed more polymorphism as compared to the other examined loci, indicating that these were more variable in the population.
  • Significant differences were detected between the observed and expected genotypic frequencies for the PGD and PGM loci. The p-value for these differences were less than 0.05 and 0.01 respectively, meaning these differences are statistically significant and not due to random chance.

Data Estimates and Implications

  • The study also provided estimates for individual allele frequencies, observed and expected phenotype frequencies, and the average heterozygosity for each polymorphic locus.
  • The allele frequency refers to how often a particular allele appears in the population. The heterozygosity rate represents the genetic diversity within a population based on the presence of different alleles at a given gene locus. A high heterozygosity rate indicates greater genetic diversity.
  • Such genetic studies are useful for understanding the genetic diversity, breed characteristics, and potential health implications in horse populations. It can also provide vital information for effective breed management and conservation strategies.

Cite This Article

APA
Uzun M, Karkhan A, Kopar A. (2002). [Eight polymorphic blood protein systems in Arab horses from Turkey]. Genetika, 37(12), 1667-1672.

Publication

ISSN: 0016-6758
NlmUniqueID: 0047354
Country: Russia (Federation)
Language: rus
Volume: 37
Issue: 12
Pages: 1667-1672

Researcher Affiliations

Uzun, M
  • Department of Physiology, Kafkas University, Kars, Turkey. metehanuzun@hotmail.com
Karkhan, A
    Kopar, A

      MeSH Terms

      • Animals
      • Blood Proteins / genetics
      • Gene Frequency
      • Genetic Markers
      • Horses / genetics
      • Phenotype
      • Polymorphism, Genetic
      • Turkey

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