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Animal genetics1988; 19(4); 359-372; doi: 10.1111/j.1365-2052.1988.tb00827.x

ELA and fertility in American Standardbred horses.

Abstract: We have analysed the effects of ELA alleles and sire-dam ELA incompatibility on two measures of fertility, gestation length and foaling rate, in American Standardbred horses. Using multivariate statistical methods, we corrected for the effects of confounding factors such as dam and sire age, parity, inbreeding, and sire-dam kinship. These analyses revealed substantial differences between Standardbred trotters and pacers in the effects of several confounding factors. There appear to be no ELA effects on gestation length in either trotters or pacers. However our results suggest that there may be ELA effects on foaling rate associated with specific dam alleles, with sire-dam incompatibility, and possibly with specific sire alleles, and that these effects differ between trotters and pacers.
Publication Date: 1988-01-01 PubMed ID: 3232864DOI: 10.1111/j.1365-2052.1988.tb00827.xGoogle Scholar: Lookup
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Summary

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This research article explores the influence of ELA alleles and parent incompatibility on the fertility rates and gestation length in American Standardbred horses, with a special focus on the differences between trotters and pacers.

Research Objectives and Methodology

  • The aim of this study was to analyze the effects of Equine Lymphocyte Antigen (ELA) alleles and the compatibility between sire (father) and dam (mother) ELA on two fertility measures: the length of gestation and foaling (birth) rate in American Standardbred horses.
  • These horses, notably used for harness racing, are typically categorized into two types: trotters and pacers, depending on their gait. This factor was taken into account in the study.
  • The researchers used multivariate statistical methods, a set of statistical techniques used when there is more than one outcome variable, to correct for the effects of external factors (known as confounding factors). These included the age of the parent horses, their parity (number of offspring), their level of inbreeding, and their kinship.

Key Findings

  • The analysis showed notable differences between Standardbred trotters and pacers in the effects of several confounding factors. The paper doesn’t specify what these differences are; that information would likely be found in the full report.
  • Contrary to typical expectations, they found no effects of ELA on the length of gestation in either trotters or pacers.
  • However, the researchers did suggest possible ELA effects on foaling rate. These effects were associated with certain mother (dam) alleles, incompatibility between the parents, and potentially with specific father (sire) alleles.
  • It was observed that these ELA effects on foaling rate vary between trotters and pacers, pointing to the possibility that categorization of the horses into trotters and pacers affect the impact of ELA on their fertility.

Implications

  • The findings of this study could potentially be critical for breeders and those in the racing industry to better understand and improve fertility rates in American Standardbred horses.
  • The observations may also go a long way in enhancing our overall understanding of how genetics and their interaction with different types of gaits affect fertility in horses.

Cite This Article

APA
MacCluer JW, Bailey E, Weitkamp LR, Blangero J. (1988). ELA and fertility in American Standardbred horses. Anim Genet, 19(4), 359-372. https://doi.org/10.1111/j.1365-2052.1988.tb00827.x

Publication

ISSN: 0268-9146
NlmUniqueID: 8605704
Country: England
Language: English
Volume: 19
Issue: 4
Pages: 359-372

Researcher Affiliations

MacCluer, J W
  • Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78284.
Bailey, E
    Weitkamp, L R
      Blangero, J

        MeSH Terms

        • Age Factors
        • Animals
        • Blood Group Antigens / genetics
        • Breeding
        • Female
        • Fertility
        • Gait
        • Gene Frequency
        • Horses / genetics
        • Horses / physiology
        • Major Histocompatibility Complex
        • Male
        • Pregnancy
        • Sex Factors
        • Time Factors

        Grant Funding

        • HD-14487 / NICHD NIH HHS