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Home / Equine Research Bank / Arch Virol / Electron microscopic studies on equine infectious anemia vir...
Archives of virology1977; 55(4); 335-340; doi: 10.1007/BF01315055

Electron microscopic studies on equine infectious anemia virus (EIAV). Brief report.

Abstract: Morphological studies of EIAV reveal knobs on the surface of the particles, conically and tubularly shaped cores, budding particles with dense crescents directly underlying the plasma membrane, and distinct intracytoplasmic structures in infected cells.
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Publication Date: 1977-01-01 PubMed ID: 202230DOI: 10.1007/BF01315055Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article focuses on examining the morphological characteristics of the Equine Infectious Anemia Virus (EIAV) using electron microscopic studies.

Morphological Studies of EIAV

The main part of the research centers around understanding the morphological features of the Equine Infectious Anemia Virus (EIAV). Some key observations include:

  • Knobs on the Surface of EIAV: The study observed small protrusions or ‘knobs’ on the surface of the virus particles. These may play a crucial role in interacting with the host cell and initiating viral infection.
  • Conically and Tubularly Shaped Cores: The researchers found that the core, or the central part of the virus where the genetic material is contained, is conically and tubularly shaped. This is significant as the shape of the core may influence how the virus behaves within the host cell.
  • Budding Particles with Dense Crescents: The study noticed budding particles with dense, moon-shaped areas directly under the plasma membrane of the virus. Budding is a stage in the virus’s lifecycle when it leaves the host cell, taking some cell membrane to form a new virus particle. Dense crescents may have a role in this process and, therefore, in the replication of the virus.
  • Distinct Intracytoplasmic Structures: The research identified unique structures within the virus-infected cell’s cytoplasm. These structures could bring forth more understanding of how the virus alters the infected cell’s internal environment.

Implications of the Research

  • This study contributes to a more comprehensive understanding of the EIAV’s morphology and potential mechanisms of interaction with the host cells. By identifying key structural elements on the virus’s surface could help in designing strategies to block these interactions, potentially stopping the virus from invading new cells.
  • The recognition of distinct intracytoplasmic structures also offers new insights into the alterations induced in the host cells by the viral invasion, paving the way for therapeutic interventions that could possibly revert these changes or render them harmless.

Cite This Article

APA
Weiland F, Matheka HD, Coggins L, Hatner D. (1977). Electron microscopic studies on equine infectious anemia virus (EIAV). Brief report. Arch Virol, 55(4), 335-340. https://doi.org/10.1007/BF01315055

Publication

Archives of virology
ISSN: 0304-8608
NlmUniqueID: 7506870
Country: Austria
Language: English
Volume: 55
Issue: 4
Pages: 335-340

Researcher Affiliations

Weiland, F
    Matheka, H D
      Coggins, L
        Hatner, D

          MeSH Terms

          • Animals
          • Cell Membrane / ultrastructure
          • Cytoplasm / ultrastructure
          • In Vitro Techniques
          • Infectious Anemia Virus, Equine / ultrastructure
          • Microscopy, Electron
          • Vacuoles / ultrastructure
          • Virion / ultrastructure

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          Citations

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