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Endoscopic appearance of gastric lesions in foals: 94 cases (1987-1988).

Abstract: Of 183 foals examined by use of gastroendoscopy during 1987 and 1988, 94 had gastric lesions. Sixty-eight of 120 foals in the 1- to 85-day-old age range had endoscopically confirmed gastric lesions, and 26 of 63 foals in the 90- to 310-day-old age range had gastric lesions. Lesions were observed most frequently in the stratified squamous mucosal epithelium, particularly adjacent to the margo plicatus. Lesions were observed in the gastric glandular mucosa in 26 of the 94 foals with gastric lesions, and with a greater frequency in foals with a clinical disorder than in foals with no disorder (27% vs 3%). In young foals, lesions were consistently observed in the stratified squamous mucosal epithelium adjacent to the margo plicatus along the greater curvature of the stomach at 2 specific sites. These lesions were frequently associated with desquamation of the stratified squamous mucosal epithelium, which was observed in 69 of the 82 foals less than or equal to 30 days old and in 13 of the 101 foals greater than 30 days old. Lesions in the stratified squamous mucosal epithelium adjacent to the margo plicatus were associated with concurrent clinical disorders in foals greater than 90 days old, but developed with identical frequency in foals less than 90 days old with or without a clinical disorder. Lesions in the stratified squamous mucosal epithelium along the lesser curvature of the stomach were observed only in foals with concurrent clinical disorder, and with a higher frequency in foals greater than 90 days old than in younger foals (24% vs 3%).
Publication Date: 1989-10-15 PubMed ID: 2808108
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  • Journal Article

Summary

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This research paper discusses the findings of a study that examined the prevalence and characteristics of gastric lesions in foals, using gastroendoscopy over a period of two years (1987-1988). The findings suggest a high occurrence of these lesions, particularly in foals of specific age ranges, and a correlation with clinical disorders.

Introduction and Methodology

  • The study’s aim was to explore the behaviour and incidence of gastric lesions in foals. This was driven by the necessity for better understanding of gastric disorders in horses of a young age. The exploration was done through gastroendoscopy, an imaging technique used to visualize the horse’s stomach.
  • The research spanned over two years, from 1987 to 1988, and involved 183 foals. These were divided into two age groups, 1-85 days old and 90-310 days old. This distinction was important as the researchers wanted to know if age affected the occurrence of gastric lesions.

Findings

  • Of the total 183 foals examined, 94 were identified with gastric lesions. The division in age depicts a higher possibility of gastric lesions appearing in the younger set of foals (1-85 days old), while the older set (90-310 days) were less affected.
  • Primarily, the study found that the lesions were most prevalent in the foals’ stratified squamous mucosal epithelium, especially near the margo plicatus, an area in the horse’s stomach. The gastric glandular mucosa, another zone in the stomach, also showed gastric lesions but with much less frequency.
  • When the results were investigated to understand the association between gastric lesions and clinical disorders, the research showed that lesions in the gastric glandular mucosa occurred more frequently in foals diagnosed with a disease.

Conclusion

  • In conclusion, the study revealed that young foals are more prone to developing gastric lesions, particularly in the stratified squamous mucosal epithelium around the margo plicatus section of the stomach.
  • In addition, there was a strong correlation between the presence of gastric lesions and concurrent clinical disorders, particularly in foals older than 90 days. However, in younger foals, such lesions appeared with or without any associated clinical disorder.
  • These findings provide valuable insights for veterinarians, allowing for better early detection and treatment plans specifically tailored according to the age and health conditions of the young equine patients.

Cite This Article

APA
Murray MJ. (1989). Endoscopic appearance of gastric lesions in foals: 94 cases (1987-1988). J Am Vet Med Assoc, 195(8), 1135-1141.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 195
Issue: 8
Pages: 1135-1141

Researcher Affiliations

Murray, M J
  • Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Leesburg 22075.

MeSH Terms

  • Animals
  • Animals, Newborn
  • Diarrhea / pathology
  • Diarrhea / veterinary
  • Epithelium / pathology
  • Gastric Mucosa / pathology
  • Gastroscopy / veterinary
  • Horse Diseases / pathology
  • Horses
  • Retrospective Studies
  • Stomach / pathology
  • Stomach Diseases / pathology
  • Stomach Diseases / veterinary

Citations

This article has been cited 5 times.
  1. Albanese V, Munsterman A, Klohnen A. Prevalence of Gastric Ulceration in Horses with Enterolithiasis Compared with Horses with Simple Large Intestinal Obstruction.. Vet Sci 2022 Oct 25;9(11).
    doi: 10.3390/vetsci9110587pubmed: 36356064google scholar: lookup
  2. Hewetson M, Venner M, Volquardsen J, Sykes BW, Hallowell GD, Vervuert I, Fosgate GT, Tulamo RM. Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in weanling foals.. Acta Vet Scand 2018 Apr 13;60(1):24.
    doi: 10.1186/s13028-018-0377-5pubmed: 29653546google scholar: lookup
  3. Okai K, Taharaguchi S, Orita Y, Yokota H, Taniyama H. Comparative endoscopic evaluation of normal and ulcerated gastric mucosae in Thoroughbred foals.. J Vet Med Sci 2015 Apr;77(4):449-53.
    doi: 10.1292/jvms.14-0334pubmed: 25648790google scholar: lookup
  4. Birkmann K, Junge HK, Maischberger E, Wehrli Eser M, Schwarzwald CC. Efficacy of omeprazole powder paste or enteric-coated formulation in healing of gastric ulcers in horses.. J Vet Intern Med 2014 May-Jun;28(3):925-33.
    doi: 10.1111/jvim.12341pubmed: 24628650google scholar: lookup
  5. Sandin A, Skidell J, Häggström J, Girma K, Nilsson G. Post-mortem findings of gastric ulcers in Swedish horses up to one year of age: a retrospective study 1924-1996.. Acta Vet Scand 1999;40(2):109-20.
    doi: 10.1186/BF03547028pubmed: 10605127google scholar: lookup