Endoscopic evaluation of changes in gastric lesions of Thoroughbred foals.
Abstract: Gastroendoscopic examinations were conducted on thirty-two 2- to 60-day-old Thoroughbred foals on 5 breeding farms. Repeat gastroendoscopic examinations were performed 35 to 135 days after the initial examination, with the age of foals ranging from 39 to 190 days. On initial endoscopic examination, lesions consisting of ulcers and/or erosions were most prevalent in the stratified squamous epithelial mucosa adjacent to the margo plicatus along the greater curvature of the stomach (15 of 32 foals), and were observed much less frequently at other sites within the stomach. In addition to ulcers and erosions, squamous epithelial desquamation at the margo plicatus was observed in 16 of 19 foals less than 30 days old and in 3 of 13 foals 30 to 60 days old, and was not seen in any foal on repeat endoscopy. At the time of repeat endoscopic examination, the frequency of ulcers and erosions at the margo plicatus was significantly (P less than 0.01) less than at initial examination (4 of 32 foals vs 15 of 32 foals). Lesions had healed in 14 of the 15 foals with lesions at the margo plicatus on the initial examination. Lesions were observed in the glandular mucosa of the fundus in 3 of 32 foals on initial examination and in 6 of 32 foals reexamined. Lesions in the glandular fundus observed on initial examination had healed in 2 of 3 foals, and of the 6 foals with glandular mucosal lesions on reexamination, 5 had developed lesions since the initial examination.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Date: 1990-05-15 PubMed ID: 2347755
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- Journal Article
Summary
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This study involves the endoscopic evaluation of gastric lesions in young Thoroughbred foals, and the changes observed in these lesions over time. The research found that lesions were most common in a specific region of the stomach and showed significant reduction upon reexamination.
Study Design and Participants
- The study was conducted on 32 Thoroughbred foals, aged 2 to 60 days, from five breeding farms.
- Each foal underwent an initial gastroendoscopic examination, followed by a second, repeat examination 35 to 135 days later. During the repeat examination, the foals’ age ranged from 39 to 190 days.
Initial Examination Findings
- On the initial endoscopic examination, gastric lesions (ulcers and/or erosions) were most frequently observed in the stratified squamous epithelial mucosa adjacent to the margo plicatus along the greater curvature of the stomach. This occurred in 15 out of the 32 foals.
- These lesions were less common at other sites within the stomach.
- Desquamation (shedding of the outermost membrane or layer) at the margo plicatus was noted in 16 of 19 foals aged less than 30 days and in 3 of 13 foals aged 30 to 60 days. This condition was not observed during the repeat endoscopy.
Follow-up Examination Findings
- The number of foals with ulcers and erosions at the margo plicatus was significantly lower on the second examination (4 out of 32) as compared to the initial examination (15 out of 32).
- 14 out of the 15 foals with initial lesions at the margo plicatus had healed by the time of the repeat examination.
- On initial examination, lesions were observed in the glandular mucosa of the fundus (the upper part of the stomach) in 3 out of 32 foals, and in 6 of 32 foals upon reexamination. Two out of three initial lesions had healed, but 5 out of the 6 foals with lesions on reexamination were new cases that had developed after the initial examination.
Summary
The research offers valuable insights into the prevalence and healing progress of gastric lesions in young Thoroughbred foals. The initial findings showed a high prevalence of lesions in the squamous epithelial mucosa region of the stomach. However, the subsequent analysis found a significant reduction in these gastric lesions, indicating healing over time. Lesions in the fundus region were less frequent but showed a slight increase over time.
Cite This Article
APA
Murray MJ, Grodinsky C, Cowles RR, Hawkins WL, Forfa RJ, Luba NK.
(1990).
Endoscopic evaluation of changes in gastric lesions of Thoroughbred foals.
J Am Vet Med Assoc, 196(10), 1623-1627.
Publication
Researcher Affiliations
- Marion duPont Scott Equine Medical Center, Virgina-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute.
MeSH Terms
- Animals
- Gastric Mucosa / pathology
- Gastroscopy / veterinary
- Horse Diseases / pathology
- Horses
- Stomach / pathology
- Stomach Diseases / pathology
- Stomach Diseases / veterinary
- Stomach Ulcer / pathology
- Stomach Ulcer / veterinary
- Videotape Recording
Citations
This article has been cited 1 times.- Buote M. Cholangiohepatitis and pancreatitis secondary to severe gastroduodenal ulceration in a foal. Can Vet J 2003 Sep;44(9):746-8.
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