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Home / Equine Research Bank / Vet Surg / Enhancing prosthesis stability at the cricoid cartilage in e...
Veterinary surgery : VS2024; doi: 10.1111/vsu.14115

Enhancing prosthesis stability at the cricoid cartilage in equine laryngoplasty using 3-D-printed laryngeal clamps: An ex vivo model study.

Abstract: To assess a three-dimensional (3-D)-printed laryngeal clamp (LC) designed to enhance the anchoring of laryngeal prostheses at the cricoid cartilage. Methods: Ex vivo biomechanical study. Methods: A total of 22 equine larynges. Methods: Two experimental groups included larynges with standard prosthetic laryngoplasty (PL; n = 10) and larynges with prosthetic laryngoplasty modified with laryngeal clamps (PLLC; n = 10). All constructs underwent 3000 cycles of tension loading and a single tension to failure. Recorded biomechanical parameters included maximum load, actuator displacement, and construct failure. Finite element analysis (FEA) was performed on one PL and one PLLC construct. Results: The maximum load at single tension to failure was 183.7 ± 46.8 N for the PL construct and 292.7 ± 82.3 N for the PLLC construct (p = .003). Actuator displacement at 30 N was 1.7 ± 0.5 mm and 2.7 ± 0.7 mm for the PL and PLLC constructs, respectively (p = .011). The cause of PL constructs failure was mostly tearing through the cartilage whereas the PLLC constructs failed through fracture of the cricoid cartilage (p = .000). FEA revealed an 11-fold reduction in the maximum equivalent plastic strain, a four-fold reduction in maximum compressive stress, and a two-fold increase in the volume of engaged cartilage in PLLC constructs. Conclusions: The PLLC constructs demonstrated superior performance in biomechanical testing and FEA compared to standard PL constructs. Conclusions: The use of 3-D-printed laryngeal clamps may enhance the outcomes of laryngoplasty in horses. In vivo studies are necessary to determine the feasibility of performing laryngoplasty using the laryngeal clamp in horses.
© 2024 The Authors. Veterinary Surgery published by Wiley Periodicals LLC on behalf of American College of Veterinary Surgeons.
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Publication Date: 2024-06-05 PubMed ID: 38840447DOI: 10.1111/vsu.14115Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research focuses on examining the effectiveness of a 3-D printed laryngeal clamp (LC) in enhancing prosthesis stability at the cricoid cartilage in equine laryngoplasty. The results suggest that the implementation of this 3-D printed laryngeal clamp during a laryngoplasty procedure in horses may result in improved outcomes.

Introduction and Objectives

  • The study was conducted with the aim of evaluating a three-dimensional (3-D)-printed laryngeal clamp (LC), a novel tool designed to improve the anchoring of laryngeal prostheses at the cricoid cartilage in horses.
  • The effectiveness of this tool was assessed in enhancing the stability of prostheses in equine laryngoplasty, a surgical procedure used to treat airway obstruction in horses.

Materials and Methods

  • An ex vivo biomechanical study was carried out on 22 equine larynges.
  • The larynges were divided into two groups: those with standard prosthetic laryngoplasty (PL; n = 10) and larynges on which prosthetic laryngoplasty was performed with the aid of laryngeal clamps (PLLC; n = 10).
  • Biomechanical parameters including maximum load, actuator displacement, and construct failure were recorded after subjecting constructs to 3000 cycles of tension loading and a single tension to failure.
  • Finite element analysis (FEA) was performed on one PL and one PLLC construct for an in-depth assessment of the localized forces, stress, and strain within the constructs.

Results

  • The PLLC constructs demonstrated better performance under failure tension, showing an increased maximum load compared to the PL constructs.
  • The actuator displacement, or the lateral movement of the implants, was also notably higher in the PLLC constructs.
  • Failure modes of the constructs differed, with the PL constructs mainly failing through tearing of the cartilage, while the PLLC constructs failed via fracture of the cricoid cartilage.
  • The FEA revealed significant reductions in maximum equivalent plastic strain and maximum compressive stress, alongside an increase in the volume of engaged cartilage, in the PLLC constructs as opposed to the PL constructs.

Conclusions

  • The results confirm that the 3-D printed laryngeal clamps proved to enhance the biomechanical performance of the laryngeal prostheses in ex vivo equine laryngoplasty models.
  • These findings suggest that the use of these clamps in laryngoplasty procedures could potentially improve surgical outcomes in horses.
  • The researchers recommend conducting in vivo studies to further validate the feasibility and effectiveness of performing laryngoplasty using the laryngeal clamp in horses.

Cite This Article

APA
Grzeskowiak R, Schumacher J, Omidi O, Bowers K, Cassone LMC, Abedi R, Hespel AM, Mulon PY, Anderson DE. (2024). Enhancing prosthesis stability at the cricoid cartilage in equine laryngoplasty using 3-D-printed laryngeal clamps: An ex vivo model study. Vet Surg. https://doi.org/10.1111/vsu.14115

Publication

Veterinary surgery : VS
ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English

Researcher Affiliations

Grzeskowiak, Remigiusz
  • College of Veterinary Medicine, Large Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.
Schumacher, Jim
  • College of Veterinary Medicine, Large Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.
Omidi, Omid
  • Tickle College of Engineering, Mechanical, Aerospace and Biomedical Engineering, The University of Tennessee, Knoxville, Tennessee, USA.
Bowers, Kristin
  • College of Veterinary Medicine, Large Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.
Cassone, Lynne M C
  • College of Agriculture, Food and Environment, Veterinary Diagnostic Laboratory, The University of Kentucky, Lexington, Kentucky, USA.
Abedi, Reza
  • Tickle College of Engineering, Mechanical, Aerospace and Biomedical Engineering, The University of Tennessee, Knoxville, Tennessee, USA.
Hespel, Adrien-Maxence
  • College of Veterinary Medicine, Small Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.
Mulon, Pierre-Yves
  • College of Veterinary Medicine, Large Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.
Anderson, David E
  • College of Veterinary Medicine, Large Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.

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