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Veterinary microbiology1987; 14(3); 211-214; doi: 10.1016/0378-1135(87)90107-6

Epidemiology of Rhodococcus equi infection in horses.

Abstract: Current understanding of the epidemiology of Rhodococcus equi infection on horse farms is reviewed. Infection is widespread in herbivores and their environment, because herbivore manure supplies the simple organic acid substrates on which the organism thrives. There is a progressive development of infection in the soil on horse farms with prolonged use, because: (1) there is a continual supply of nutrients; (2) the organism multiplies progressively as temperatures rise; (3) the bacterium has a robust nature. While this aerobic organism fails to multiply in the largely anaerobic intestine of the adult horse, multiplication to very large numbers may occur in the intestine of a foal in its first 8-12 weeks of life. Farms used for foal breeding over many years may thus become particularly dangerous for foals. Areas for future study include the effectiveness of decontamination, manure-removal programs and dust reduction in reducing challenge to susceptible foals.
Publication Date: 1987-08-01 PubMed ID: 3314106DOI: 10.1016/0378-1135(87)90107-6Google Scholar: Lookup
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Summary

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The research article revolves around the prevalence of Rhodococcus equi infection in horses, highlighting how factors like herbivore manure, warm temperatures, and farm usage contribute to its spread. The study also underscores the vulnerability of foals within their first 12 weeks, and the potential value of decontamination and manure-removal programs for prevention.

Rhodococcus equi Infection and Its Prevalence

  • The article provides an overview of the epidemiology of Rhodococcus equi infection among horses. Rhodococcus equi is a bacterium that poses a threat to the health of foals, primarily causing pneumonia, and less frequently, enteritis.
  • The infection is widespread in herbivores and their environment due to the simple organic acid substrates present in the herbivore manure, which serves as a thriving medium for the bacterium.

Role of Environmental Factors and Farm Conditions

  • There seems to be a progressive development of the infection on horse farms that have been in use for a long period of time. This is attributable to a continuous supply of nutrients, progressive multiplication of the organism as temperatures rise, and the robust nature of the bacterium.
  • Areas on farms that have been used extensively for foal breeding can become particularly dangerous for young foals due to the high level of bacterial contamination.

Specific Risks for Young Foals

  • While Rhodococcus equi fails to multiply in the largely anaerobic intestine of an adult horse, it can proliferate to a large extent in the intestine of a foal during its first 8-12 weeks of life, making them particularly susceptible to the infection.

Focused Areas for Future Study

  • Given the serious implications of the infection, the article sheds light on the areas that require further investigation.
  • These include the effectiveness of decontamination efforts, manure-removal programs, and dust reduction measures, all of which could play a critical part in reducing the challenges faced by susceptible foals.

Cite This Article

APA
Prescott JF. (1987). Epidemiology of Rhodococcus equi infection in horses. Vet Microbiol, 14(3), 211-214. https://doi.org/10.1016/0378-1135(87)90107-6

Publication

ISSN: 0378-1135
NlmUniqueID: 7705469
Country: Netherlands
Language: English
Volume: 14
Issue: 3
Pages: 211-214

Researcher Affiliations

Prescott, J F
  • Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, University of Guelph, Ontario, Canada.

MeSH Terms

  • Actinomycetales Infections / epidemiology
  • Actinomycetales Infections / veterinary
  • Animals
  • Horse Diseases / epidemiology
  • Horse Diseases / microbiology
  • Horses
  • Pneumonia / epidemiology
  • Pneumonia / microbiology
  • Pneumonia / veterinary
  • Rhodococcus

Citations

This article has been cited 7 times.
  1. Erganis O, Sayin Z, Hadimli HH, Sakmanoglu A, Pinarkara Y, Ozdemir O, Maden M. The effectiveness of anti-R. equi hyperimmune plasma against R. equi challenge in thoroughbred Arabian foals of mares vaccinated with R. equi vaccine.. ScientificWorldJournal 2014;2014:480732.
    doi: 10.1155/2014/480732pubmed: 24982958google scholar: lookup
  2. Gurel V, Lambert K, Page AE, Loynachan AT, Huges K, Timoney JF, Fettinger M, Horohov DW, McMichael J. Streptolysin-O/antibiotics adjunct therapy modulates site-specific expression of extracellular matrix and inflammatory genes in lungs of Rhodococcus equi infected foals.. Vet Res Commun 2013 Jun;37(2):145-54.
    doi: 10.1007/s11259-013-9557-ypubmed: 23475766google scholar: lookup
  3. Buckley T, McManamon E, Stanbridge S. Resistance studies of erythromycin and rifampin for Rhodococcus equi over a 10-year period.. Ir Vet J 2007 Dec 1;60(12):728-31.
    doi: 10.1186/2046-0481-60-12-728pubmed: 21851690google scholar: lookup
  4. Kuskie KR, Smith JL, Wang N, Carter CN, Chaffin MK, Slovis NM, Stepusin RS, Cattoi AE, Takai S, Cohen ND. Effects of location for collection of air samples on a farm and time of day of sample collection on airborne concentrations of virulent Rhodococcus equi at two horse breeding farms.. Am J Vet Res 2011 Jan;72(1):73-9.
    doi: 10.2460/ajvr.72.1.73pubmed: 21194338google scholar: lookup
  5. Prescott JF, Machang'u R, Kwiecien J, Delaney K. Prevention of foal mortality due to Rhodococcus equi pneumonia on an endemically affected farm.. Can Vet J 1989 Nov;30(11):871-5.
    pubmed: 17423454
  6. Hamrock D, Azmi FH, O'Donnell E, Gunning WT, Philips ER, Zaher A. Infection by Rhodococcus equi in a patient with AIDS: histological appearance mimicking Whipple's disease and Mycobacterium avium-intracellulare infection.. J Clin Pathol 1999 Jan;52(1):68-71.
    doi: 10.1136/jcp.52.1.68pubmed: 10343616google scholar: lookup
  7. Prescott JF. Rhodococcus equi: an animal and human pathogen.. Clin Microbiol Rev 1991 Jan;4(1):20-34.
    doi: 10.1128/CMR.4.1.20pubmed: 2004346google scholar: lookup