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Home / Equine Research Bank / Vet Res Commun / Equine anhidrosis: a review of pathophysiologic mechanisms.
Veterinary research communications1983; 6(4); 249-264; doi: 10.1007/BF02214921

Equine anhidrosis: a review of pathophysiologic mechanisms.

Abstract: Anhidrosis is loss of the ability to sweat. The problem is seen in horses kept in a hot humid climate, and it may cause severe impairment of thermoregulation in the equine athlete. British Thoroughbreds imported to her tropical colonies are the earliest recorded cases, and since then the syndrome has come to be described as one of Thoroughbreds, usually performance athletes, undergoing acclimatization to heat and humidity. A recent epidemiologic study of cases in Florida has shown, however, that many different breeds, and long time inhabitants of a hot climate, may be affected. Equine sweat glands are of the apocrine type, and sweating is stimulated by direct local release of epinephrine from adrenergic nerve endings and by circulating epinephrine. Lack of sweating could be due to a number of possible flaws in a sequence from central nervous stimulation through sweat stimulation and secretion to delivery of sweat to the skin surface. The most likely possibilities are inadequate sweat gland response due to habituation of receptors to a high circulating level of epinephrine and occlusion of the sweat ducts by keratin plugs. Hormonal or metabolic imbalance may play a role both in the onset and secondary signs associated with anhidrosis.
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Publication Date: 1983-09-01 PubMed ID: 6359664DOI: 10.1007/BF02214921Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The article is a review of the causes and potential mechanisms behind anhidrosis, a condition in which horses lose their ability to sweat, that often impacts equine athletes living in hot and humid climates. This condition can severely hinder their ability to regulate body temperature.

Understanding Anhidrosis in Horses

  • Anhidrosis is a condition that causes horses to lose the ability to sweat. This impairment is often seen in equine athletes who live in hot, humid climates and can seriously impact their ability to regulate their body temperature.
  • While the condition has been recorded in horses for centuries, with one of the earliest documented cases being British Thoroughbreds imported to tropical colonies, recent research in Florida has shown that the condition can affect many different breeds and even horses who have lived in a hot climate for a prolonged period.

Causes and Mechanisms of Anhidrosis

  • The article explores the possible mechanisms that could lead to anhidrosis in horses. Normally, equine sweat glands are stimulated to produce sweat by the local release of a hormone called epinephrine from nerve endings and its circulation in the blood.
  • The inability to sweat could be a result of various flaws along the path from the initial stimulation of the central nervous system to the eventual secretion and delivery of sweat to the skin’s surface.
  • Potential causes suggested by the article include a diminished response from the sweat glands due to habituation of the receptors to constantly high levels of epinephrine, or the obstruction of sweat ducts by keratin plugs.

Hormonal Imbalance and Anhidrosis

  • Moreover, the authors suggest that hormonal or metabolic imbalances could play a part in both initiating anhidrosis and also in secondary indicators associated with the condition. Thus, the article emphasizes the need for further research to understand this complex condition and to develop effective treatments.

Cite This Article

APA
Warner A, Mayhew IG. (1983). Equine anhidrosis: a review of pathophysiologic mechanisms. Vet Res Commun, 6(4), 249-264. https://doi.org/10.1007/BF02214921

Publication

Veterinary research communications
ISSN: 0165-7380
NlmUniqueID: 8100520
Country: Switzerland
Language: English
Volume: 6
Issue: 4
Pages: 249-264

Researcher Affiliations

Warner, A
    Mayhew, I G

      MeSH Terms

      • Acclimatization
      • Adrenergic Fibers / physiology
      • Animals
      • Body Temperature Regulation
      • Climate
      • Epinephrine / pharmacology
      • Florida
      • Horse Diseases / physiopathology
      • Horses
      • Humidity
      • Hypohidrosis / physiopathology
      • Hypohidrosis / veterinary
      • Physical Exertion
      • Sweat / analysis
      • Sweat Glands / anatomy & histology
      • Sweat Glands / drug effects
      • Sweat Glands / innervation
      • Sweat Glands / physiopathology

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