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The Veterinary clinics of North America. Equine practice2017; 33(1); 163-179; doi: 10.1016/j.cveq.2016.11.005

Equine Cardiovascular Therapeutics.

Abstract: Heart disease can be defined as any abnormality of the heart whether it is a cardiac dysrhythmia or structural heart disease, either congenital or acquired. Heart failure occurs when a cardiac abnormality results in the inability of the heart to pump enough blood to meet the body's needs. Heart disease can be present without leading to heart failure. Heart failure, however, is a consequence of heart disease. There are 4 main areas where the clinician can intervene to improve cardiac output with heart failure: preload, afterload, myocardial contractility, and heart rate.
Publication Date: 2017-03-23 PubMed ID: 28325177DOI: 10.1016/j.cveq.2016.11.005Google Scholar: Lookup
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Summary

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The research article centers on the different treatment possibilities for heart disease in horses. It explores how interventions could be made in four primary areas: preload, afterload, myocardial contractility, and heart rate to enhance cardiac output in case of heart failure.

Understanding Heart Disease and Heart Failure

  • Heart disease in horses can be designated as any abnormal collection of conditions affecting the heart. This could range from cardiac dysrhythmia, which is an irregular heartbeat, to structural heart conditions. These conditions could be either congenital, meaning present from birth, or acquired, meaning developed during the horse’s life.
  • The research suggests that the presence of heart disease does not automatically result in heart failure. Heart failure occurs when a present heart abnormality hampers the heart’s ability to pump enough blood to satisfy the body’s requirements.
  • According to the study, heart failure is not a separate disease on its own, but a consequence of heart disease.

Intervention Methods in Equine Cardiovascular Therapeutics

  • The research identifies four key areas wherein a clinician can intervene to enhance the cardiac output in situations of heart failure. Cardiac output refers to the quantity of blood the heart pumps to cater to the body’s needs.
  • These areas are preload, afterload, myocardial contractility, and heart rate. Preload refers to the volume of blood in the heart before contraction, while afterload relates to the resistance that the heart must overcome to pump blood effectively.
  • Myocardial contractility is another critical factor, signifying the heart’s capability to contract and subsequently pump blood. Intervening in this area could involve measures to increase the efficiency of the heart’s contractions.
  • Lastly, adjustments to the horse’s heart rate could also form part of the treatment. Increasing or decreasing the heart rate in response to the body’s needs could result in an improved cardiac output.

Conclusion

  • Through these identified intervention areas, the research details that effective treatment of heart failure can be mediated. By manipulating these factors through various treatments, the prospect of improving the heart’s function and handling heart disease more effectively in horses could be viable.

Cite This Article

APA
Sleeper MM. (2017). Equine Cardiovascular Therapeutics. Vet Clin North Am Equine Pract, 33(1), 163-179. https://doi.org/10.1016/j.cveq.2016.11.005

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 33
Issue: 1
Pages: 163-179

Researcher Affiliations

Sleeper, Meg M
  • Cardiology, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 Southwest 16th Avenue, PO Box 100126, Gainesville, FL 32610-0126, USA. Electronic address: margaretmsleeper@ufl.edu.

MeSH Terms

  • Animals
  • Heart Diseases / diagnosis
  • Heart Diseases / therapy
  • Heart Diseases / veterinary
  • Horse Diseases / diagnosis
  • Horse Diseases / therapy
  • Horses
  • Humans

Citations

This article has been cited 2 times.
  1. Agne GF, Jung SW, Wooldridge AA, Duran SH, Ravis W, Toribio R. Pharmacokinetic and pharmacodynamic properties of orally administered torsemide in healthy horses. J Vet Intern Med 2018 Jul;32(4):1428-1435.
    doi: 10.1111/jvim.15213pubmed: 29770976google scholar: lookup
  2. Kheder MH, Bailey SR, Dudley KJ, Sillence MN, de Laat MA. Equine glucagon-like peptide-1 receptor physiology. PeerJ 2018;6:e4316.
    doi: 10.7717/peerj.4316pubmed: 29404215google scholar: lookup