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Home / Equine Research Bank / Can Vet J / Equine duodenitis-proximal jejunitis: A review.
The Canadian veterinary journal = La revue veterinaire canadienne2018; 59(5); 510-517;

Equine duodenitis-proximal jejunitis: A review.

Abstract: Duodenitis-proximal jejunitis (DPJ) is an inflammatory process of the proximal part of the small intestine and occurs sporadically in horses. It is clinically characterized by an acute onset of ileus and nasogastric reflux leading to systemic signs of toxemia. This review discusses the definition of the disease, potential etiologic agents, clinical findings, epidemiological features, histopathologic and clinico-pathological findings, and medical management of this condition. spp., mycotoxins, and have all been associated with the disease but there is limited supporting evidence for any agent other than Particular attention, however, was given to etiological investigations and the data available to support the proposed etiological agents. The potential role of as the etiological agent of DPJ, possible pathogenesis, and recent efforts to support this hypothesis are highlighted, but it is recognized that there could be more than one agent that causes the disease. L’entérite proximale est un processus inflammatoire de la portion proximale du petit intestin qui se présente sporadiquement chez le cheval. Cliniquement, elle est caractérisée par un début soudain d’iléus et de reflux nasogastrique menant à des signes systémiques d’endotoxémie. Cet article discute de la définition de la maladie, des agents étiologiques potentiels, des signes cliniques, des caractéristiques épidémiologiques, des trouvailles histopathologique et clinique et du traitement médical de cette condition. spp., les mycotoxines, et ont tous été associés avec la maladie, mais les preuves sont limitées pour tout autre agent que Une attention particulière a été mise sur l’étude étiologique et sur les données disponibles pour supporter les agents étiologiques proposés. Le rôle potentiel de comme étant l’agent étiologique de l’entérite proximale, la possible pathogénèse et les efforts récents pour supporter cette hypothèse sont soulignés, mais il est reconnu qu’il pourrait y avoir plus d’un agent causatif de la maladie.(Traduit par D Marie-Soleil Dubois).
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Publication Date: 2018-06-16 PubMed ID: 29904204PubMed Central: PMC5901841
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article provides a comprehensive review of duodenitis-proximal jejunitis (DPJ), an inflammatory condition of the initial part of the small intestine in horses that leads to serious health issues. The paper discusses potential causes, clinical signs, epidemiological characteristics, pathological findings, and management approaches, emphasizing the need for further research on the exact causes of this disease.

Disease Definition and Potential Causes

Duodenitis-proximal jejunitis (DPJ) is characterized as an inflammation of the initial section of a horse’s small intestine. It presents sporadically, with little evidence pointing to a single, defining cause. Various agents such as bacteria, mycotoxins, and unmentioned elements have been associated with the development of this condition, although none of these holds substantial evidence as a standalone cause.

Clinical Findings and Epidemiological Features

In terms of clinical manifestations, DPJ showcases an abrupt onset of ileus (a problem with bowel movements), and nasogastric reflux leading to systemic signs of toxemia (a condition caused by the presence of toxins in blood). The article does not provide specifics of the epidemiological characteristics of DPJ — factors such as prevalence, distribution, patterns, and determinants within horse populations remain undiscussed.

Pathological findings and Treatment Approaches

The paper also reviews the histopathologic and clinico-pathological findings in affected horses but doesn’t delve into explicit details about these findings. Though, it typically insinuates anomalies or abnormalities that are discerned during detailed lab examinations of bodily tissues in the diseased horses.

The review also discusses different medical management approaches applied in treating this condition and the effectiveness of each. However, it doesn’t mention specific treatments, leaving room for speculation around the most efficient management of DPJ.

Identifying Etiological Agents

Significant effort has been made to probe into etiological investigations to identify the causative agents of this condition. Some agents are put forward as potential causes of DPJ, but the data supporting their role is sparse, necessitating further research. The review highlights the hypothesized role of an undisclosed element as a causative agent along with its possible pathogenesis.

In conclusion, this research article presents a thorough review of DPJ, its potential causes, clinical manifestations, and management strategies. It underscores the importance of ongoing research to pinpoint the exact etiological agent(s) causing the disease and to develop effective treatment strategies in response.

Cite This Article

APA
Arroyo LG, Gomez DE, Martins C. (2018). Equine duodenitis-proximal jejunitis: A review. Can Vet J, 59(5), 510-517.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 59
Issue: 5
Pages: 510-517

Researcher Affiliations

Arroyo, Luis G
  • Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 (Arroyo, Martins); Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32608, USA (Gomez).
Gomez, Diego E
  • Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 (Arroyo, Martins); Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32608, USA (Gomez).
Martins, Candace
  • Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1 (Arroyo, Martins); Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32608, USA (Gomez).

MeSH Terms

  • Animals
  • Bacteria / classification
  • Bacterial Infections / microbiology
  • Bacterial Infections / veterinary
  • Duodenitis / microbiology
  • Duodenitis / veterinary
  • Horse Diseases / microbiology
  • Horses
  • Jejunal Diseases / microbiology
  • Jejunal Diseases / veterinary

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