Equine endometrial biopsy reviewed: observation, interpretation, and application of histopathologic data.
Abstract: The equine endometrial biopsy, an important tool in equine reproduction science, has experienced a rich period of increasing knowledge, development, and application over the past 40 y. Much of the foundational work in this field was conducted by Dr. Robert M. Kenney. In view of his recent passing, this review is dedicated to our alumnus, Dr. Robert M. Kenney (OSU, 1954). In this manuscript, we pay tribute to Kenney-eponymous for the equine endometrial biopsy grading system-by reviewing the procedure. We present this review in three parts: 1) how observational data are acquired; 2) how these data are interpreted; and 3) how these data are applied in equine reproduction science and medicine.
Copyright © 2011 Elsevier Inc. All rights reserved.
Publication Date: 2011-02-26 PubMed ID: 21356552DOI: 10.1016/j.theriogenology.2010.12.013Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Historical Article
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research article discusses the evolution, interpretation and application of equine endometrial biopsy, a key technique in horse reproduction science. The procedure, highly influenced by the work of the late Dr. Robert M. Kenney, is reviewed in depth.
Equine Endometrial Biopsy
- The equine endometrial biopsy is an essential tool utilized within the discipline of equine reproduction science. This manuscript critically reviews the procedure, delving into its history, development, and practical uses over the course of the past four decades.
- Considerable emphasis is given to the pioneering work of Dr. Robert M. Kenney. Known for his meaningful contributions to this field, Kenney’s name is synonymous with the equine endometrial biopsy grading system.
Observational Data Acquisition
- The first section of this review focuses on how observational data pertaining to equine endometrial biopsy is gathered. Each step of the biopsy process is explored, providing readers with a detailed understanding of the methodology behind this diagnostic procedure.
Interpretation of Data
- The second section of the paper delves into the complex task of interpreting the data obtained from an endometrial biopsy. A good interpretation depends on an accurate understanding of the horse’s reproductive status, the biopsy results, and a comparison of the two.
Application of Data in Equine Reproduction Science and Medicine
- The final section of this review discusses how the data derived from the equine endometrial biopsy are applied in the fields of equine reproduction science and medicine. The reliability and utility of this tool make it an essential part of diagnosing and treating conditions that affect a mare’s reproductive system.
Cite This Article
APA
Snider TA, Sepoy C, Holyoak GR.
(2011).
Equine endometrial biopsy reviewed: observation, interpretation, and application of histopathologic data.
Theriogenology, 75(9), 1567-1581.
https://doi.org/10.1016/j.theriogenology.2010.12.013 Publication
Researcher Affiliations
- Department of Pathobiology, Oklahoma State University, Stillwater, OK, USA.
MeSH Terms
- Age Factors
- Animals
- Biopsy / history
- Biopsy / methods
- Biopsy / veterinary
- Endometrium / microbiology
- Endometrium / pathology
- Estrus / physiology
- Female
- History, 20th Century
- History, 21st Century
- Horse Diseases / pathology
- Horses
- Pathology, Veterinary / history
- Pathology, Veterinary / methods
- Pregnancy
- Pregnancy Complications / pathology
- Pregnancy Complications / veterinary
- Seasons
- Uterine Diseases / pathology
- Uterus / microbiology
- Uterus / pathology
Citations
This article has been cited 15 times.- Alpoim-Moreira J, Fernandes C, Rebordão MR, Costa AL, Bliebernicht M, Nunes T, Szóstek-Mioduchowska A, Skarzynski DJ, Ferreira-Dias G. Collagen Type III as a Possible Blood Biomarker of Fibrosis in Equine Endometrium.. Animals (Basel) 2022 Jul 21;12(14).
- Westendorf J, Wobeser B, Epp T. IIB or not IIB, part 2: assessing inter-rater and intra-rater repeatability of the Kenney-Doig scale in equine endometrial biopsy evaluation.. J Vet Diagn Invest 2022 Mar;34(2):215-225.
- Westendorf J, Wobeser B, Epp T. IIB or not IIB, part 1: retrospective evaluation of Kenney-Doig categorization of equine endometrial biopsies at a veterinary diagnostic laboratory and comparison with published reports.. J Vet Diagn Invest 2022 Mar;34(2):206-214.
- Woźna-Wysocka M, Rybska M, Błaszak B, Jaśkowski BM, Kulus M, Jaśkowski JM. Morphological changes in bitches endometrium affected by cystic endometrial hyperplasia - pyometra complex - the value of histopathological examination.. BMC Vet Res 2021 Apr 26;17(1):174.
- Cequier A, Sanz C, Rodellar C, Barrachina L. The Usefulness of Mesenchymal Stem Cells beyond the Musculoskeletal System in Horses.. Animals (Basel) 2021 Mar 25;11(4).
- Martí A, Serrano A, Pastor J, Rigau T, Petkevičiuté U, Calvo MÀ, Arosemena EL, Yuste A, Prandi D, Aguilar A, Rivera Del Alamo MM. Endometrial Status in Queens Evaluated by Histopathology Findings and Two Cytological Techniques: Low-Volume Uterine Lavage and Uterine Swabbing.. Animals (Basel) 2021 Jan 5;11(1).
- Quartuccio M, Cristarella S, Medica P, Fazio E, Mazzullo G, Rifici C, Liotta L, Satué K. Endometrial Cytology During the Different Phases of the Estrous Cycle in Jennies: New Evidences.. Animals (Basel) 2020 Jun 19;10(6).
- Milan B, Sampaio BFB, Silva EVDCE, Leal CRB, Navarro B, Gomes DC. The gynecological examination in Pantaneiro mares.. Anim Reprod 2020 Mar 17;17(1):e20190031.
- Vance CK, King EH, Bowers SD, Ryan PL, Walters K, Shappell NW. Reproductive Performance of Mares Fed Dietary Zearalenone.. Front Vet Sci 2019;6:423.
- Crociati M, Capomaccio S, Mandara MT, Stradaioli G, Sylla L, Monaci M, Cappelli K. Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season.. BMC Vet Res 2019 Dec 21;15(1):465.
- de Holanda AGB, da Silva Leite J, Consalter A, da Silva KVGC, Dos Santos Batista BP, Fonseca ABM, Brandão FZ, Ferreira AMR. Expression of interleukins 6 and 10 and population of inflammatory cells in the equine endometrium: diagnostic implications.. Mol Biol Rep 2019 Apr;46(2):2485-2491.
- Rink BE, Amilon KR, Esteves CL, French HM, Watson E, Aurich C, Donadeu FX. Isolation and characterization of equine endometrial mesenchymal stromal cells.. Stem Cell Res Ther 2017 Jul 12;8(1):166.
- Sikora M, Król J, Nowak M, Stefaniak T, Aubertsson G, Kozdrowski R. The usefulness of uterine lavage and acute phase protein levels as a diagnostic tool for subclinical endometritis in Icelandic mares.. Acta Vet Scand 2016 Sep 7;58(1):50.
- Kendziorski JA, Belcher SM. Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A.. Reprod Toxicol 2015 Dec;58:119-30.
- Buczkowska J, Kozdrowski R, Nowak M, Raś A, Staroniewicz Z, Siemieniuch MJ. Comparison of the biopsy and cytobrush techniques for diagnosis of subclinical endometritis in mares.. Reprod Biol Endocrinol 2014 Apr 4;12:27.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists