FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Clin Case Rep / Equine eosinophilic keratitis in horses: 28 cases (2003-2013...
Clinical case reports2015; 3(12); 1000-1006; doi: 10.1002/ccr3.350

Equine eosinophilic keratitis in horses: 28 cases (2003-2013).

Abstract: This retrospective case series evaluates husbandry and environmental conditions in relation to eosinophilic keratitis in horses. While no associations were found between disease and husbandry practices or specific environmental factors such as humidity or temperature, an increased prevalence of presentation in summer months was identified in this population of horses.
Get Full Text
Publication Date: 2015-11-02 PubMed ID: 26734136PubMed Central: PMC4693706DOI: 10.1002/ccr3.350Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Case Reports

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study looks at the connection between husbandry and environmental factors and eosinophilic keratitis in horses over a decade, and notes a higher number of cases during the summer, despite no specific link to other factors like weather conditions or horse care practices.

Study Objectives and Methodology

  • This research was a retrospective case series looking into the relationship between eosinophilic keratitis in horses and several factors encompassing husbandry and environmental conditions over a 10-year span, from 2003 to 2013.
  • Eosinophilic keratitis is an inflammatory condition of the horse’s cornea and conjunctiva involving eosinophils, a type of white blood cell. The exact cause remains unclear though it is believed to be an immune-mediated response, possibly to environmental allergens.
  • The researchers gathered data on 28 cases of this disease over the studied time period.

Findings and Conclusions

  • No identifiable patterns or associations were found between the incidence of the disease and specific husbandry practices, which includes ways in which the horses are taken care of such as feeding, grooming, housing etc.
  • Moreover, no direct correlations were found between the disease and particular environmental conditions, such as humidity or temperature, indicating that these factors may not play a significant role in the development of this condition in horses.
  • However, the study did identify an increased prevalence of eosinophilic keratitis presentation during the summer months. Although the research does not offer a firm explanation for this increased summer presentation, it does suggest that there might be underlying seasonal factors or allergens at play.
  • In conclusion, while the study found no direct links between husbandry practices or specific environmental factors and eosinophilic keratitis, the increased incidence of the disease in summer months suggests that further research is needed to understand the specific seasonal factors contributing to this trend.

Cite This Article

APA
Edwards S, Clode AB, Gilger BC. (2015). Equine eosinophilic keratitis in horses: 28 cases (2003-2013). Clin Case Rep, 3(12), 1000-1006. https://doi.org/10.1002/ccr3.350

Publication

Clinical case reports
ISSN: 2050-0904
NlmUniqueID: 101620385
Country: England
Language: English
Volume: 3
Issue: 12
Pages: 1000-1006

Researcher Affiliations

Edwards, Sydney
  • Department of Surgical and Radiological Sciences School of Veterinary Medicine University of California-Davis One Shields Avenue Davis California 95616.
Clode, Alison B
  • Department of Clinical Sciences North Carolina State University College of Veterinary Medicine 1052 William Moore Drive Raleigh North Carolina 27607.
Gilger, Brian C
  • Department of Clinical Sciences North Carolina State University College of Veterinary Medicine 1052 William Moore Drive Raleigh North Carolina 27607.

References

This article includes 30 references
  1. Morgan RV, Abrmas KL. Feline eosinophilic keratitis: a retrospective study of 54 cases (1989–1994). Vet. Comp. Ophthalmol. 1996;6:131–134.
  2. Clode AB. Diseases and surgery of the cornea. 2011;Pp. 181–266 in Gilger B. C., ed. Equine opthalmology. 2nd ed Elsevier Saunders, Maryland Heights, MO.
  3. Lassaline-Utter M, Miller C, Wotman KL. Eosinophilic keratitis in 46 eyes of 27 horses in the Mid-Atlantic United States (2008-2012).. Vet Ophthalmol 2014 Sep;17(5):311-20.
    pubmed: 23763548doi: 10.1111/vop.12076google scholar: lookup
  4. Ramsey DT, Whiteley HE, Gerding PA Jr, Valdez RA. Eosinophilic keratoconjunctivitis in a horse.. J Am Vet Med Assoc 1994 Nov 1;205(9):1308-11.
    pubmed: 7698943
  5. Yamagata M, Wilkie DA, Gilger BC. Eosinophilic keratoconjunctivitis in seven horses.. J Am Vet Med Assoc 1996 Oct 1;209(7):1283-6.
    pubmed: 8837652
  6. Jennings AF. Eosinophilic keratoconjunctivitis in a donkey. 2007;British Association of Veterinary Ophthalmology Annual Conference.
  7. Kainzbauer C, Steinborn R, Mair‐Scorpio G. PCR‐mediated detection of bovine papillomavirus E5 and L1 DNA in equine eosinophilic conjunctivitis/keratitis. 2008;39th Annual Meeting of the American College of Veterinary Ophthalmologists 11:413–429.
  8. Sandberg CA, Herring IP, Schorling JJ. Ulcerative eosinophilic keratoconjunctivitis in three horses: clinical course and characterization by electron microscopy. 2008;39th Annual Meeting of the American College of Veterinary Ophthalmologists 11:413–429.
  9. Kafarnik C. Equine eosinophilic keratitis. Comp. Anim. 2010;15:4–6.
  10. Chisholm WH. Feline eosinophilic keratitis.. Can Vet J 1989 May;30(5):438.
    pmc: PMC1681271pubmed: 17423334
  11. Nasisse MP, Glover TL, Moore CP, Weigler BJ. Detection of feline herpesvirus 1 DNA in corneas of cats with eosinophilic keratitis or corneal sequestration.. Am J Vet Res 1998 Jul;59(7):856-8.
    pubmed: 9659551
  12. Andrew SE. Ocular manifestations of feline herpesvirus.. J Feline Med Surg 2001 Mar;3(1):9-16.
    pubmed: 11716625doi: 10.1053/jfms.2001.0110google scholar: lookup
  13. Moore PA. Feline corneal disease.. Clin Tech Small Anim Pract 2005 May;20(2):83-93.
    pubmed: 15948422doi: 10.1053/j.ctsap.2004.12.012google scholar: lookup
  14. Malik R, Lessels NS, Webb S, Meek M, Graham PG, Vitale C, Norris JM, Power H. Treatment of feline herpesvirus-1 associated disease in cats with famciclovir and related drugs.. J Feline Med Surg 2009 Jan;11(1):40-8.
    pubmed: 19154974doi: 10.1016/j.jfms.2008.11.012google scholar: lookup
  15. Spiess AK, Sapienza JS, Mayordomo A. Treatment of proliferative feline eosinophilic keratitis with topical 1.5% cyclosporine: 35 cases.. Vet Ophthalmol 2009 Mar-Apr;12(2):132-7.
    pubmed: 19261170doi: 10.1111/j.1463-5224.2008.00679.xgoogle scholar: lookup
  16. Grinninger P, Sanchez R, Kraijer-Huver IM, Kitslaar WJ, Schoemaker NJ, Grinwis GC, Boevé MH. Eosinophilic keratoconjunctivitis in two rabbits.. Vet Ophthalmol 2012 Jan;15(1):59-65.
    pubmed: 22051177doi: 10.1111/j.1463-5224.2011.00920.xgoogle scholar: lookup
  17. Schmidt GM, Krehbiel JD, Coley SC, Leid RW. Equine ocular onchocerciasis: histopathologic study.. Am J Vet Res 1982 Aug;43(8):1371-5.
    pubmed: 7103221
  18. Gilger BC. Equine ophthalmology. 2013;Pp. 1584–1585 in Gelat K. N., ed. Veterinary opthalmology. 5th ed. John Wiley & Sons Inc, Ames, IO.
  19. Moawad FJ, Veerappan GR, Wong RK. Eosinophilic esophagitis.. Dig Dis Sci 2009 Sep;54(9):1818-28.
    pubmed: 19554448doi: 10.1007/s10620-009-0873-6google scholar: lookup
  20. Sila GH, Morreale RJ, Lorimer DW. A retrospective evaluation of the diamond burr superficial keratectomy in the treatment of spontaneous chronic epithelial defects in dogs from 2006 to 2008. 2009;40th Annual Meeting of the American College of Veterinary Ophthalmologists 40:404.
  21. Straumann A, Aceves SS, Blanchard C, Collins MH, Furuta GT, Hirano I, Schoepfer AM, Simon D, Simon HU. Pediatric and adult eosinophilic esophagitis: similarities and differences.. Allergy 2012 Apr;67(4):477-90.
    pubmed: 22313241doi: 10.1111/j.1398-9995.2012.02787.xgoogle scholar: lookup
  22. Weller PF, Bubley GJ. The idiopathic hypereosinophilic syndrome.. Blood 1994 May 15;83(10):2759-79.
    pubmed: 8180373
  23. Miranda C, Busacker A, Balzar S, Trudeau J, Wenzel SE. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation.. J Allergy Clin Immunol 2004 Jan;113(1):101-8.
    pubmed: 14713914doi: 10.1016/j.jaci.2003.10.041google scholar: lookup
  24. Vasiliou JE, Lui S, Walker SA, Chohan V, Xystrakis E, Bush A, Hawrylowicz CM, Saglani S, Lloyd CM. Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease.. Allergy 2014 Oct;69(10):1380-9.
    pmc: PMC4329404pubmed: 24943330doi: 10.1111/all.12465google scholar: lookup
  25. Utter ME, Keenan D, Makkreel L. Eosinophilic keratoconjunctivitis in 19 mares on a Standardbred farm. Vet. Ophthalmol. 2010;13:407–423.
  26. Liacouras CA, Spergel JM, Ruchelli E, Verma R, Mascarenhas M, Semeao E, Flick J, Kelly J, Brown-Whitehorn T, Mamula P, Markowitz JE. Eosinophilic esophagitis: a 10-year experience in 381 children.. Clin Gastroenterol Hepatol 2005 Dec;3(12):1198-206.
    pubmed: 16361045doi: 10.1016/s1542-3565(05)00885-2google scholar: lookup
  27. Ingle SB, Patle YG, Murdeshwar HG, Pujari GP. A case of early eosinophilic gastroenteritis with dramatic response to steroids.. J Crohns Colitis 2011 Feb;5(1):71-2.
    pubmed: 21272810doi: 10.1016/j.crohns.2010.10.002google scholar: lookup
  28. Kim NI, Jo YJ, Song MH, Kim SH, Kim TH, Park YS, Eom WY, Kim SW. [Clinical features of eosinophilic gastroenteritis].. Korean J Gastroenterol 2004 Oct;44(4):217-23.
    pubmed: 15505434
  29. Chen MJ, Chu CH, Lin SC, Shih SC, Wang TE. Eosinophilic gastroenteritis: clinical experience with 15 patients.. World J Gastroenterol 2003 Dec;9(12):2813-6.
    pmc: PMC4612059pubmed: 14669340doi: 10.3748/wjg.v9.i12.2813google scholar: lookup
  30. Hsu YQ, Lo CY. A case of eosinophilic gastroenteritis.. Hong Kong Med J 1998 Jun;4(2):226-228.
    pubmed: 11832578

Citations

This article has been cited 1 times.
  1. Knickelbein KE, Luethy D, Thomasy SM, Reilly C, Strom AR, Lassaline ME. Equine eosinophilic keratoconjunctivitis in California: retrospective study of 47 eyes from 29 cases (1993-2017). Vet Ophthalmol 2019 Jul;22(4):510-519.
    doi: 10.1111/vop.12621pubmed: 30706617google scholar: lookup
Subscribe to our newsletter
Join 99,001 horse owners like you who receive our email updates on horse health and nutrition.