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Equine veterinary journal2008; 40(4); 422-428; doi: 10.2746/042516408X312932

Equine gastrointestinal motility research: where we are and where we need to go.

Abstract: Equine gastrointestinal motility is a central issue in cases of equine colic, post operative convalescence and alimentary conditions encountered in practice. There are significant syndromes of intestinal dysmotility in the horse such as obstructive disorders and post operative ileus that are still poorly understood. This review describes the various areas of research that aim to elucidate the pathogenesis of intestinal hypo- or hypermotility by research methods, which include studies at the cellular level, and those that employ in vitro or in vivo techniques of evaluating the physiology and mechanical means of ingesta transit through the alimentary tract. The review discusses future directions for studies which will hopefully lead to better understanding and appropriate measures for diagnosis, therapy and prevention of ileus and other motility disorders.
Publication Date: 2008-05-20 PubMed ID: 18487107DOI: 10.2746/042516408X312932Google Scholar: Lookup
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  • Journal Article
  • Review

Summary

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This research article is about the current status and future directions of studies regarding the gastrointestinal motility in horses, primarily focusing on issues like equine colic, post-operative convalescence, and intestinal disorders.

Overview of Research Topic

  • The subject of this research is equine gastrointestinal motility, a critical aspect in cases of equine colic, post operative convalescence and alimentary conditions observed in veterinary practice.
  • This research also touches on significant syndromes of intestinal dysmotility in horses, such as obstructive disorders and post operative ileus, which are currently poorly understood due to lack of comprehensive research.

Research Approaches and Techniques

  • The research methods used to examine the pathogenesis of intestinal hypo- or hypermotility include studies at the cellular level to understand the biochemistry and physiology of these issues and in vitro or in vivo techniques for visual and mechanical evaluation.
  • These methods help in understanding the physiology and mechanical means of ingesta transit (passage of food and drink) through the alimentary tract of the horse.

Future Directions for the Study

  • The review suggests plans for future studies that aim to enhance our understanding and devise better diagnostic measures, treatments, and preventive measures for ileus and other motility disorders in horses.
  • The goal is to fill the gaps in current understanding and establish comprehensive strategies for tackling syndromes of intestinal dysmotility, thereby aiming to improve the health and well-being of horses.

Cite This Article

APA
Hudson NP, Merritt AM. (2008). Equine gastrointestinal motility research: where we are and where we need to go. Equine Vet J, 40(4), 422-428. https://doi.org/10.2746/042516408X312932

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 40
Issue: 4
Pages: 422-428

Researcher Affiliations

Hudson, N P H
  • Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Easter Bush, Roslin, Midlothian, UK.
Merritt, A M

    MeSH Terms

    • Animals
    • Gastrointestinal Diseases / etiology
    • Gastrointestinal Diseases / prevention & control
    • Gastrointestinal Diseases / veterinary
    • Gastrointestinal Motility / physiology
    • Gastrointestinal Transit / physiology
    • Horse Diseases / etiology
    • Horse Diseases / prevention & control
    • Horses / physiology

    References

    This article includes 111 references

    Citations

    This article has been cited 4 times.
    1. MacNicol JL, Pearson W. Gastrin and Nitric Oxide Production in Cultured Gastric Antral Mucosa Are Altered in Response to a Gastric Digest of a Dietary Supplement. Front Vet Sci 2021;8:684203.
      doi: 10.3389/fvets.2021.684203pubmed: 34671658google scholar: lookup
    2. Beder NA, Mourad AA, Aly MA. Ultrasonographic evaluation of the effects of the administration of neostigmine and metoclopramide on duodenal, cecal, and colonic contractility in Arabian horses: A comparative study. Vet World 2020 Nov;13(11):2447-2451.
    3. Laus F, Fratini M, Paggi E, Faillace V, Spaterna A, Tesei B, Fettucciari K, Bassotti G. Effects of Single-Dose Prucalopride on Intestinal Hypomotility in Horses: Preliminary Observations. Sci Rep 2017 Jan 27;7:41526.
      doi: 10.1038/srep41526pubmed: 28128322google scholar: lookup
    4. Mömke S, Sickinger M, Rehage J, Doll K, Distl O. Transcription factor binding site polymorphism in the motilin gene associated with left-sided displacement of the abomasum in German Holstein cattle. PLoS One 2012;7(4):e35562.
      doi: 10.1371/journal.pone.0035562pubmed: 22536407google scholar: lookup