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The American journal of tropical medicine and hygiene1980; 29(5); 984-988; doi: 10.4269/ajtmh.1980.29.984

Equine Getah virus infection: isolation of the virus from racehorses during an enzootic in Japan.

Abstract: A primary enzootic of equine Getah virus infection involving 722 of 1,903 racehorses occurred at a training center in Japan between September and November of 1978. Sixty-two viral agents were isolated from the plasma of 209 sick horses which exhibited pyrexia with rectal temperatures ranging from 38.5--40 degrees C, urticarial rash on various portions of the body, and edema of the hind legs. The viruses were antigenically related to the AMM 2021, Haruna, and Sagiyama strains of Getah virus. Infection and disease were produced experimentally in horses when inoculated by the intramuscular or intranasal routes.
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Publication Date: 1980-09-01 PubMed ID: 6254385DOI: 10.4269/ajtmh.1980.29.984Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research is about an outbreak of Getah virus infection that impacted horse racing in Japan in 1978, where 722 out of 1,903 racehorses were affected. The study examines the symptoms, viral agents, and experimental infection of the disease.

Background and Objective

  • The focus of the study is on an extensive outbreak of the Getah virus among racehorses at a training center in Japan that occurred between September and November 1978. The researchers aimed to study and isolate the Getah virus from affected horses to forge a better understanding of the disease pathogenesis and transmission.

OBSERVATIONS

  • During this time, the researchers observed that out of 1,903 horses, 722 were affected by the virus, indicating a significant infection rate.
  • The typical symptoms observed in the infected horses were raised body temperature (38.5–40 degrees C), development of an urticarial rash on various parts of the body, and edema (swelling) of the hind legs.
  • From 209 sick horses, the researchers isolated 62 viral agents, providing a rich sample for further analysis and study.

VIRAL STRAINS AND INFECTION METHODS

  • The isolated viruses were found to be related to the AMM 2021, Haruna, and Sagiyama strains of the Getah virus, suggesting a possible link or shared characteristics among these strain types.
  • Additionally, the researchers were able to induce Getah virus infection in healthy horses experimentally. It was found that the virus could infect equines when delivered either through an intramuscular injection or via the intranasal route. This finding provided insights into the transmission pathways of the Getah virus.

Significance

  • This research contributed significantly towards the understanding of the Getah virus, its symptoms, viral strains, and methods of transmission among equines. With this information, prevention and control methods for this virus could be improved, possibly helping to mitigate future outbreaks in the racehorse population.

Cite This Article

APA
Kamada M, Ando Y, Fukunaga Y, Kumanomido T, Imagawa H, Wada R, Akiyama Y. (1980). Equine Getah virus infection: isolation of the virus from racehorses during an enzootic in Japan. Am J Trop Med Hyg, 29(5), 984-988. https://doi.org/10.4269/ajtmh.1980.29.984

Publication

The American journal of tropical medicine and hygiene
ISSN: 0002-9637
NlmUniqueID: 0370507
Country: United States
Language: English
Volume: 29
Issue: 5
Pages: 984-988

Researcher Affiliations

Kamada, M
    Ando, Y
      Fukunaga, Y
        Kumanomido, T
          Imagawa, H
            Wada, R
              Akiyama, Y

                MeSH Terms

                • Alphavirus / ultrastructure
                • Animals
                • Horse Diseases / diagnosis
                • Horse Diseases / microbiology
                • Horses
                • Japan
                • Togaviridae Infections / diagnosis
                • Togaviridae Infections / microbiology
                • Togaviridae Infections / veterinary

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