Equine glaucoma.
Abstract: Glaucoma is a diverse group of vision-impairing disorders that have as a common bond an elevation of intraocular pressure(IOP) to a level incompatible with the health of the eye. Glaucoma can be congenital, primary, or secondary. Congenital equine glaucoma is associated with developmental abnormalities of the iridocorneal angle or, in many cases, with the more severe anterior segment dysgenesis.
Publication Date: 2004-07-24 PubMed ID: 15271429DOI: 10.1016/j.cveq.2004.04.002Google Scholar: Lookup
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Summary
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This research examines the disease of equine glaucoma, a severe neurodegenerative ocular condition in horses causing blindness, predominantly found as a secondary condition to uveitis. The study discusses diagnostic strategies and therapy options but identifies that current prognosis for equine vision remains poor.
Understanding Equine Glaucoma
- Despite the in-depth knowledge of human glaucoma, our understanding of equine glaucoma remains underdeveloped. This disease is characterized by the progressive loss of retinal ganglion cells and their axons that form the optic nerve and eventually cause blindness.
- The disease is complex, driven by multiple factors and develops most commonly alongside uveitis. This piece points to the possibility that equine glaucoma may be frequently underdiagnosed or misdiagnosed in horses with uveitis.
- Increased awareness amongst clinicians, coupled with portable tonometers, or pressure meters, is improving diagnosis accuracy.
Treatment of Equine Glaucoma
- The focus of therapy for equine glaucoma is managing and reducing the production of aqueous humor – the clear fluid in the front of the eye, between the cornea and the lens. This relief strategy can be achieved via both medical and surgical methods.
- Despite these interventions, the research outlines that the long-term vision prognosis for horses suffering from glaucoma remains poor. Therefore, it underlines an urgent need for improved understanding, diagnostic methods and treatments for equine glaucoma.
Cite This Article
APA
Wilkie DA, Gilger BC.
(2004).
Equine glaucoma.
Vet Clin North Am Equine Pract, 20(2), 381-vii.
https://doi.org/10.1016/j.cveq.2004.04.002 Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, The Ohio State University, 601 Vernon Tharp Street, Columbus, OH 43210, USA. wilkie.1@osu.edu
MeSH Terms
- Animals
- Glaucoma / diagnosis
- Glaucoma / surgery
- Glaucoma / therapy
- Glaucoma / veterinary
- Horse Diseases / diagnosis
- Horse Diseases / surgery
- Horse Diseases / therapy
- Horses
- Intraocular Pressure
- Ocular Hypertension / etiology
- Ocular Hypertension / veterinary
References
This article includes 35 references
Citations
This article has been cited 7 times.- Shnaiderman-Torban A, Pe'er O, Gustafsson K, Tatz A, Brizi M, Soback S, Abu Ahmad W, Magen R, Ofri R, Kelmer G. The effect of systemic acetazolamide administration on intraocular pressure in healthy horses-A preliminary study. Vet Ophthalmol 2025 Jan;28(1):66-72.
- Knickelbein KE, Lassaline ME, Kim S, Thomasy SM. Ultrasound biomicroscopy of the equine iridocorneal angle. Equine Vet J 2022 Nov;54(6):1153-1158.
- Wollanke B, Gerhards H, Ackermann K. Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis. Microorganisms 2022 Feb 7;10(2).
- Mustikka MP, Pietilä EM, Mykkänen AK, Grönthal TSC. Comparison of two rebound tonometers in healthy horses. Vet Ophthalmol 2020 Sep;23(5):892-898.
- Slenter IJM, Hermans H, Ensink JM, Willems DS, Veraa S, Grinwis GCM, Boevé MH. Clinical, ultrasonographic, and histopathologic findings in seven horses with Descemet's membrane detachment: A case series. Vet Ophthalmol 2020 Jan;23(1):181-189.
- Von Zup M, Lassaline M, Kass PH, Miller PE, Thomasy SM. Effects of 0.2% brimonidine and 0.2% brimonidine-0.5% timolol on intraocular pressure and pupil size in normal equine eyes. Equine Vet J 2017 Nov;49(6):810-814.
- Andrade SF, Kupper DS, Pinho LF, Franco EC, Prataviera MV, Duarte RR, Junqueira JR. Evaluation of the Perkins handheld applanation tonometer in horses and cattle. J Vet Sci 2011 Jun;12(2):171-6.
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