Equine leucocyte antigen system: progress and potential.
Abstract: Leucocyte antigens are cell-surface glycoproteins, the structure of which is under the genetic control of a chromosome region called the major histocompatibility complex. Progress in the study of the equine leucocyte antigen (ELA) system has been achieved in two ways; first by the fact that the ELA system is intensively investigated in different laboratories all over the world and parallels can be drawn to the information gained from research in more extensively studied species, and secondly by the collaborative efforts of the participants in three international workshops. The potential applications of the ELA system and areas of further investigation are discussed.
Publication Date: 1985-07-01 PubMed ID: 3908093DOI: 10.1111/j.2042-3306.1985.tb02493.xGoogle Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
- Review
Summary
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The research article focuses on the advancements and potential applications in the study of the equine leucocyte antigen (ELA) system, a cell-surface glycoprotein that is genetically controlled by a chromosome region.
Understanding Equine Leucocyte Antigen
- Leucocyte antigens are cell-surface glycoproteins. They are an essential part of the immune system and play a crucial role in the body’s response to foreign substances or invaders.
- The structure of these antigens is genetically controlled by a chromosome region known as the major histocompatibility complex. In horses, this is referred to as the equine leucocyte antigen (ELA) system.
Research Progress
- The progress in the study of the ELA system has been made in two key ways.
- First is through an intense investigation of the ELA system in different laboratories around the world. These investigations allow for the drawing of parallels to research done in other species, further extending our understanding of these antigens.
- The second way is via the collaborative efforts of researchers in international workshops. These collaborations facilitate the sharing of expertise, findings, and new methodologies, thus accelerating our progress in this field.
- The article further discusses potential applications of the ELA system and future areas of investigation.
- Understanding the ELA system could have significant implications for immunology and veterinary medicine. This is because it can potentially improve our knowledge of immune response in horses and might pave the way for more effective treatments and vaccines.
Future Areas of Study and Potential Applications
Cite This Article
APA
Matthews SM.
(1985).
Equine leucocyte antigen system: progress and potential.
Equine Vet J, 17(4), 265-268.
https://doi.org/10.1111/j.2042-3306.1985.tb02493.x Publication
Researcher Affiliations
MeSH Terms
- Animals
- Cytotoxicity Tests, Immunologic
- Female
- Histocompatibility Antigens Class II / immunology
- Horses / immunology
- Isoantigens / immunology
- Leukocytes / immunology
- Lymphocytes / immunology
- Major Histocompatibility Complex
- Maternal-Fetal Exchange
- Paternity
- Pregnancy
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