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The Veterinary clinics of North America. Equine practice2024; 40(3); 431-439; doi: 10.1016/j.cveq.2024.07.008

Equine Melanoma Updates.

Abstract: Melanomas are very common in older gray horses, with 80% of gray horses having at least 1 melanoma by 15 years of age. Historically considered a benign disease, it is now known that up to 66% of lesions will eventually metastasize. Melanomas may also cause local problems due to abscessation, ulceration, and interference with function of the affected areas. Treatment can be limited by size and location, but surgical resection, where possible, is likely to be the treatment of choice.
Publication Date: 2024-09-11 PubMed ID: 39266414DOI: 10.1016/j.cveq.2024.07.008Google Scholar: Lookup
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Summary

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The research paper discusses the prevalence of Melanomas—a type of skin tumor—in older gray horses and how they indeed can metastasize, contrary to prior beliefs that deemed them benign. The paper also outlines possible complications and discusses potential treatments for this condition.

Prevalence and Misconceptions of Melanomas in Horses

  • According to the study, Melanomas are prolific among gray horses—particularly those that are older. A staggering 80% of gray horses above the age of 15 present with at least one melanoma.
  • Historically, melanomas in horses have been categorized as benign. However, this research refutes those claims, emphasizing the potential for metastasis. It reveals that up to 66% of such lesions may eventually metastasize.

Negative Effects of Melanomas

  • Melanomas don’t just remain benign tumors; they may also induce a variety of local problems.
  • This research points out that a horse suffering from a melanoma may experience abscessation, ulceration, and overall disruption in the function of the affected areas.

Limited Treatment Options

  • The study points out the limitations of the treatment options currently available for melanomas in horses. Treatment feasibility can often be curtailed due to large tumor size or an inaccessible location on the horse.
  • Despite these limitations, the paper suggests surgical resection—removing part or all of the tumor—as a viable treatment option wherever possible. Specifically, surgical resection is identified as the likely treatment of choice.

Cite This Article

APA
Hollis AR. (2024). Equine Melanoma Updates. Vet Clin North Am Equine Pract, 40(3), 431-439. https://doi.org/10.1016/j.cveq.2024.07.008

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 40
Issue: 3
Pages: 431-439

Researcher Affiliations

Hollis, Anna R
  • Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK. Electronic address: arh207@cam.ac.uk.

MeSH Terms

  • Horses
  • Horse Diseases / therapy
  • Melanoma / veterinary
  • Melanoma / pathology
  • Animals
  • Skin Neoplasms / veterinary
  • Skin Neoplasms / pathology

Conflict of Interest Statement

Disclosure The author has no affiliations other than her work for the University of Cambridge.