Equine placental teratoma.
Abstract: The placenta from a 300-day-gestational age, female, Arabian equine fetus was examined. Multifocal to coalescing, 0.5- to 4-cm-diameter, white, smooth nodules covered 50% of the placenta. Microscopic evaluation of the nodules revealed undifferentiated germ cells and a haphazard arrangement of immature, mesenchymal stroma, cartilage, squamous cornifying epithelium, scattered ducts and secretory acini lined by cuboidal to columnar epithelium, and mineralized foci. No umbilicus, arrangement about an axial skeleton, or organized polarity of structures was present. The lesion was diagnosed as a placental teratoma, a lesion not reported in species other than man.
Publication Date: 2003-09-02 PubMed ID: 12949420DOI: 10.1354/vp.40-5-586Google Scholar: Lookup
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Summary
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This research study examines a case where an Arabian horse fetus was found to have a teratoma, a type of tumor, in the placenta. This type of condition has not been previously reported in any species other than humans.
Introduction to the Research
- The researchers in this study investigated the placenta of a 300-day-old Arabian horse fetus.
- Broadly, this research article explores a unique case of an equine placenta teratoma, an unusual medical condition that has not been reported in any species other than humans.
Observations and Findings
- Upon examination, the team identified multiple white nodules of varying diameters. These nodules were smooth and covered approximately half of the placenta.
- By conducting a microscopic evaluation of the nodules, the scientists discovered various cell types, including undifferentiated germ cells and an irregular arrangement of immature mesenchymal stroma, cartilage, squamous epithelium subjected to cornification, scattered ducts and secretory acini that are lined by cuboidal to columnar epithelium, in addition to mineralized foci.
Diagnosis and Significance
- No evidence of an umbilicus, arrangement about an axial skeleton, or an organized polarity of structures was present in the examined tissue.
- Based on the findings, the scientists diagnosed the lesion as a placental teratoma.
- The importance of these findings lies in the fact that this type of tumorous condition, placental teratoma, has never been previously reported in any species except humans. Thus, it opens up new areas of investigation in veterinary pathology.
Summary
- This research delineates an unusual case of a placental teratoma in a horse fetus, extending our understanding of veterinary pathology.
- The findings have the potential to stimulate more elaborate studies on teratomas in non-human species, contributing to our understanding of this form of tumor’s etiology and treatment possibilities in the veterinary field.
Cite This Article
APA
Gurfield N, Benirschke K.
(2003).
Equine placental teratoma.
Vet Pathol, 40(5), 586-588.
https://doi.org/10.1354/vp.40-5-586 Publication
Researcher Affiliations
- San Diego County Animal Disease Diagnostic Laboratory, Department of Agriculture, Weights and Measures, 5555 Overland Avenue, Building 4, San Diego, CA 92123, USA. nikos.gurfield@sdcounty.ca.gov
MeSH Terms
- Animals
- Female
- Histocytochemistry / veterinary
- Horse Diseases / pathology
- Horses
- Placenta Diseases / pathology
- Placenta Diseases / veterinary
- Pregnancy
- Teratoma / pathology
- Teratoma / veterinary
Citations
This article has been cited 2 times.- Lee SJ, Triana Garcia PA, Choi EA. Congenital oropharyngeal teratoma in a neonatal goat and brief review of extragonadal teratomas in animals. J Vet Diagn Invest 2026 Jan 29;:10406387251410495.
- Balogh O, Diab S, Parker A, de Sousa GC, Cecere JT, McCarter SJ, Sponenberg DP. Case report: Placental chorioadenoma in a primiparous pug dog. Front Vet Sci 2024;11:1505470.
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