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The Veterinary clinics of North America. Equine practice1987; 3(2); 397-403; doi: 10.1016/s0749-0739(17)30682-x

Equine protozoal myeloencephalitis.

Abstract: Equine protozoal myeloencephalitis (EPM) is a disease that produces neurologic signs of brain or spinal cord dysfunction. The causative organism is believed to be a Sarcocystis species of protozoa. A definitive diagnosis can only be made on histopathology of affected spinal cord or brain. No preventive measures or documented treatment is available at this time for suspected cases of EPM.
Publication Date: 1987-08-01 PubMed ID: 3113695DOI: 10.1016/s0749-0739(17)30682-xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research article discusses Equine protozoal myeloencephalitis (EPM), a disease in horses caused by a certain type of protozoa. The disease affects the brain or spinal cord of the animal and can only be definitively diagnosed through histopathology. Currently, there are no known preventative measures or treatments for it.

Understanding EPM

  • Equine Protozoal Myeloencephalitis (EPM) is a disease that primarily affects horses, producing neurological symptoms.
  • It is characterized by signs of brain or spinal cord dysfunction as the protozoa damage critical parts of the central nervous system.
  • The causative organism of EPM is believed to be a species of protozoa called Sarcocystis, although, actual confirmation of this is still under study.

Diagnosis of EPM

  • The research states that a definitive diagnosis of EPM can only be made using histopathology of the affected spinal cord or brain.
  • Histopathology is the microscopic examination of biological tissues to observe the appearance of diseased cells in detail.
  • This means that tissues have to be taken from the affected horse for testing, probably after it has shown significant neurological signs, or, unfortunately, post-mortem in most cases.

Lack of Prevention and Treatment

  • According to the study, there currently aren’t any preventive measures that can be taken against EPM.
  • Unhelpfully, the study also revealed that there is no documented treatment available for the suspected cases of EPM, posing a significant challenge in equine health.
  • The absence of preventive measures and definite cures underscores the need for further research into this disease, to better understand its course, effect, and possibly, to discover a cure.

Cite This Article

APA
Madigan JE, Higgins RJ. (1987). Equine protozoal myeloencephalitis. Vet Clin North Am Equine Pract, 3(2), 397-403. https://doi.org/10.1016/s0749-0739(17)30682-x

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 3
Issue: 2
Pages: 397-403

Researcher Affiliations

Madigan, J E
    Higgins, R J

      MeSH Terms

      • Animals
      • Encephalomyelitis / parasitology
      • Encephalomyelitis / pathology
      • Encephalomyelitis / veterinary
      • Horse Diseases / parasitology
      • Horse Diseases / pathology
      • Horses
      • Sarcocystosis / pathology
      • Sarcocystosis / veterinary

      Citations

      This article has been cited 2 times.
      1. Kitchen DL. Bilateral neurogenic masseter muscle atrophy in a mare. Can Vet J 1993 Aug;34(8):491-2.
        pubmed: 17424270
      2. Wilson AP, Thelen JJ, Lakritz J, Brown CR, Marsh AE. The identification of a sequence related to apicomplexan enolase from Sarcocystis neurona. Parasitol Res 2004 Nov;94(5):354-60.
        doi: 10.1007/s00436-004-1224-3pubmed: 15549383google scholar: lookup