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Home / Equine Research Bank / J Clin Microbiol / Equine rotaviruses with G14 serotype specificity circulate a...
Journal of clinical microbiology1994; 32(10); 2609-2612; doi: 10.1128/jcm.32.10.2609-2612.1994

Equine rotaviruses with G14 serotype specificity circulate among venezuelan horses.

Abstract: Two group A rotavirus strains isolated from diarrheic foals in Venezuela were classified as belonging to G14 serotype by cross-neutralization tests and on the basis of the homology of the sequenced VP7 gene. This report confirms that rotavirus strains of G14 serotype specificity circulate among equine populations.
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Publication Date: 1994-10-01 PubMed ID: 7814511PubMed Central: PMC264117DOI: 10.1128/jcm.32.10.2609-2612.1994Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article presents findings which confirm the presence of G14 serotype rotaviruses among horse populations in Venezuela, isolated from foals suffering from diarrhea.

Study Background

  • The research focuses on the investigation of rotavirus strains found in horse populations in Venezuela.
  • Rotaviruses are a type of virus that cause gastrointestinal illnesses, commonly diarrhea, which can be severe and life-threatening in young animals and humans.
  • These viruses are classified into different groups and subgroups, and one such classification is based on their “G” (glycoprotein) and “P” (protease-sensitive) types. The classification in this study was specifically on the “G” or glycoprotein type.
  • The G14 serotype of rotavirus has not been widely studied or identified as a common strain among equine populations.

Methodology

  • The researchers isolated rotavirus strains from foals (young horses) with diarrhea in Venezuela. Two Group A rotavirus strains were singled out for further study.
  • The classification of these strains as belonging to the G14 serotype was achieved through cross-neutralization tests – a method used to ascertain the identity of a virus by observing its reaction to antibodies that interact with specific viral types.
  • Furthermore, they also sequenced the VP7 gene of the isolated viruses and found homology (similarity) with the known sequence of the G14 serotype rotavirus. The VP7 gene codes for a glycoprotein which determines the “G” type of the rotavirus.

Findings and Significance

  • The research confirms that the G14 serotype rotavirus circulates among the horse populations in Venezuela.
  • This has significant implications as it expands the known diversity of rotaviruses affecting equines and may have potential impacts on diagnostic methods, treatments, and prevention strategies.
  • The discovery of G14 serotype in horses may also warrant further investigation to determine its prevalence in other equine populations around the world and to explore if the strain has possibilities of zoonotic transmission (transmission from animals to humans).

Cite This Article

APA
Ciarlet M, Reggeti F, Piña CI, Liprandi F. (1994). Equine rotaviruses with G14 serotype specificity circulate among venezuelan horses. J Clin Microbiol, 32(10), 2609-2612. https://doi.org/10.1128/jcm.32.10.2609-2612.1994

Publication

Journal of clinical microbiology
ISSN: 0095-1137
NlmUniqueID: 7505564
Country: United States
Language: English
Volume: 32
Issue: 10
Pages: 2609-2612

Researcher Affiliations

Ciarlet, M
  • Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Cientificas, Caracas.
Reggeti, F
    Piña, C I
      Liprandi, F

        MeSH Terms

        • Amino Acid Sequence
        • Animals
        • Antigens, Viral
        • Capsid / genetics
        • Capsid Proteins
        • Diarrhea / veterinary
        • Diarrhea / virology
        • Horse Diseases / virology
        • Horses / virology
        • Molecular Sequence Data
        • Neutralization Tests
        • Rotavirus / classification
        • Rotavirus / immunology
        • Rotavirus / isolation & purification
        • Serotyping

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