Equine shock wave therapy – where are we now?
Abstract: Over the past three decades, electrohydraulic extracorporeal shock wave therapy (ESWT) as a treatment modality for equine orthopaedic disorders has sparked exponential interest among practitioners, but its clinical applications are quickly evolving and a current review highlighting modernised equine clinical use is lacking. The objective of this review is to summarise the most current ESWT technology, evidence for its use, proposed mechanisms of action and clinical applications in horses while also highlighting the areas requiring further investigation. The three ways to generate a shock wave are through electrohydraulic, electromagnetic or piezoelectric mechanisms, but over the last decade, electrohydraulic systems have predominated due to the ability to focus and control a therapeutic waveform. Shock waves' primary physical effect is believed to be via mechanotransduction leading to cellular activation and downstream signalling. Experimentally, ESWT's effects on osseous, connective tissue and wound healing via various mechanisms of action have been reported both in the human and veterinary literature. Clinical trials have investigated ESWT's orthopaedic application including osteoarthritis, thoracolumbar pain, navicular syndrome, tendinopathy and proximal suspensory desmopathy, with its concomitant use with biologics representing an area of active research. Direct ESWT protocol comparisons in terms of long-term efficacy with variables of energy, depth and exposed tissue types are still lacking with evidence-based recommendations being largely anecdotal. Technical advancements to facilitate the safe and judicious use of ESWT include human and equine hearing protection, light sedation and/or patient restraint. Efforts to ensure the safe and judicious use of ESWT and its analgesic effects are ongoing.
© 2022 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.
Publication Date: 2022-10-28 PubMed ID: 36210719DOI: 10.1111/evj.13890Google Scholar: Lookup
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- Journal Article
- Review
- Clinical Examination
- Clinical Findings
- Clinical Pathology
- Clinical Signs
- Clinical Study
- Diagnosis
- Disease Diagnosis
- Disease Etiology
- Disease Management
- Disease Treatment
- Equine Diseases
- Equine Health
- Musculoskeletal System
- Orthopedics
- Pain Management
- Rehabilitation
- Treatment
- Veterinary Medicine
- Veterinary Practice
- Veterinary Procedure
- Veterinary Research
Summary
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The study provides a comprehensive review of the current applications, mechanisms, and evidence related to Electrohydraulic Extracorporeal Shock Wave Therapy (ESWT) in treating equine orthopedic conditions. It highlights the need for further investigations to establish evidence-based recommendations on the therapy’s protocols.
Current ESWT Technology and Mechanisms of Action
- Electrohydraulic Extracorporeal Shock Wave Therapy (ESWT) is a treatment technique for horse orthopedic disorders that has gained substantial interest over the past 30 years. The therapy works by generating a shock wave via three primary mechanisms – electrohydraulic, electromagnetic, or piezoelectric.
- In recent years, the electrohydraulic mechanism has become the preferred method due to its ability to focus and control therapeutic waveforms effectively.
- The primary physical impact of the shock waves is thought to be mechanotransduction, which initiates cellular activation and subsequent signaling.
Effects and Clinical Applications of ESWT
- Studies, both in human and veterinary literature, have reported the effects of ESWT on bone healing, connective tissue healing, and wound healing.
- Clinical trials have explored the application of ESWT for various orthopedic conditions like osteoarthritis, thoracolumbar pain, navicular syndrome, tendinopathy, and proximal suspensory desmopathy.
- The concurrent use of ESWT with biologics represents a significant field of ongoing research.
Techniques and Safety Measures in ESWT
- Equine and human hearing protection, light sedation, and patient restraint are some of the technical advancements implemented to ensure the safe and judicious use of ESWT.
- However, comparisons of ESWT protocols in terms of long-term efficacy, energy utilized, depth, and exposure tissue types are still lacking.
- Most recommendations are largely anecdotal, highlighting the need for further studies to provide clear, evidence-based guidelines for ESWT’s application.
Future of ESWT
- ESWT’s analgesic effects are still being investigated, pointing to the therapy’s untapped potential in pain management.
- Future efforts should focus on ensuring the safe, effective, and evidence-based use of ESWT technology.
Cite This Article
APA
Johnson SA, Richards RB, Frisbie DD, Esselman AM, McClure SR.
(2022).
Equine shock wave therapy – where are we now?
Equine Vet J, 55(4), 593-606.
https://doi.org/10.1111/evj.13890 Publication
Researcher Affiliations
- Department of Clinical Sciences, Orthopaedic Research Center at the Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
- PulseVet Shock Wave, Alpharetta, Georgia, USA.
- Department of Clinical Sciences, Orthopaedic Research Center at the Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
- Department of Clinical Sciences, Orthopaedic Research Center at the Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
- Midwest Equine Surgery and Sports Medicine, Boone, Iowa, USA.
MeSH Terms
- Humans
- Horses
- Animals
- Extracorporeal Shockwave Therapy / veterinary
- High-Energy Shock Waves / therapeutic use
- Mechanotransduction, Cellular
- Wound Healing
- Osteoarthritis / veterinary
- Musculoskeletal Diseases / veterinary
- Treatment Outcome
- Horse Diseases / drug therapy
References
This article includes 60 references
- McCarroll GD, McClure SR. Extracorporeal shock wave therapy for treatment of osteoarthritis of the Tarsometatarsal and distal Intertarsal joints of the horse.. Proc Am Assoc Equine Practnrs 2000;46:200-2.
- Revenaugh MS. Extracorporeal shock wave therapy for treatment of osteoarthritis in the horse: clinical applications.. Vet Clin North Am Equine Pract 2005;21(3):609-25.
- Trager LR, Funk RA, Clapp KS, Dahlgren LA, Were SR, Hodgson DR. Extracorporeal shockwave therapy raises mechanical nociceptive threshold in horses with thoracolumbar pain.. Equine Vet J 2020;52(2):250-7.
- McClure SE, Evans RB, Miles KG, Reinertson EL, Hawkins JF, Honnas CM. Extracorporeal shockwave therapy for treatment of navicular syndrome.. Proc Am Assoc Equine Practnrs 2004;50:316-9.
- Brown KE, Nickels FA, Caron JP, Mullineaux DR, Clayton HM. Investigation of the immediate analgesic effects of extracorporeal shock wave therapy for treatment of navicular disease in horses.. Vet Surg 2005;34(6):554-8.
- Hunter JM, McClure SR, Merritt DK, Reinertson E. Extracorporeal shockwave therapy for treatment of superficial digital flexor tendonitis in racing thoroughbreds: 8 clinical cases.. Vet Comp Orthop Traumatol 2004;17(3):152-5.
- Giunta K, Donnell JR, Donnell AD, Frisbie DD. Prospective randomized comparison of platelet rich plasma to extracorporeal shockwave therapy for treatment of proximal suspensory pain in western performance horses.. Res Vet Sci 2019;126:38-44.
- Graff J, Berding C, Pastor J. Transmission of shock waves through bone: treatment of iliac ureteral stones in a supine position.. J Urol 1990;143(170):231A.
- McClure SR, Van Sickle D, White MR. Effects of extracorporeal shock wave therapy on bone.. Vet Surg 2004;33(1):40-8.
- Johannes EJ, Kaulesar Sukul DM, Matura E. High-energy shock waves for the treatment of nonunions: an experiment on dogs.. J Surg Res 1994;57(2):246-52.
- Schaden W, Fischer A, Sailler A. Extracorporeal shock wave therapy of nonunion or delayed osseous union.. Clin Orthop Relat Res 2001;387:90-4.
- McClure S, Dorfmüller C. Extracorporeal shock wave therapy: theory and equipment.. Clin Tech Equine Pract 2003;2(4):348-57.
- Cleveland R, McAteer JA. The physics of shock wave lithotripsy.. Smith's textbook of Endourology 2007;p. 317-32 chap 38.
- Jaalouk DE, Lammerding J. Mechanotransduction gone awry.. Nat Rev Mol Cell Biol 2009;10(1):63-73.
- Chen YJ, Wurtz T, Wang C-J, Kuo Y-R, Yang KD, Huang H-C. Recruitment of mesenchymal stem cells and expression of TGF-beta 1 and VEGF in the early stage of shock wave-promoted bone regeneration of segmental defect in rats.. J Orthop Res 2004;22(3):526-34.
- Kawcak CE, Frisbie DD, McIlwraith CW. Effects of extracorporeal shock wave therapy and polysulfated glycosaminoglycan treatment on subchondral bone, serum biomarkers, and synovial fluid biomarkers in horses with induced osteoarthritis.. Am J Vet Res 2011;72(6):772-9.
- Chen JW, Stefanovski D, Haughan J, Boston R, Zoma LR, Robinson MA. Inflammatory mediators are potential biomarkers for extracorporeal shockwave therapy in horses.. Equine Vet J 2020;52(3):449-54.
- Chen Y-J, Wang C-J, Yang K-D, Kuo Y-R, Huang H-C, Huang Y-T. Extracorporeal shock waves promote healing of collagenase-induced Achilles tendinitis and increase TGF-beta1 and IGF-I expression.. J Orthop Res 2004;22(4):854-61.
- Link KA, Koenig JB, Silveira A, Plattner BL, Lillie BN. Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses.. Am J Vet Res 2013;74(2):324-32.
- Holfeld J, Tepekoylu C, Reissig C, Lobenwein D, Scheller B, Kirchmair E. Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle.. Cardiovasc Res 2016;109(2):331-43.
- Shen P-C, Chou S--H, Lu CC, Huang H-T, Chien S-H, Huang P-J. Shockwave treatment enhanced extracellular matrix production in articular chondrocytes through activation of the ROS/MAPK/Nrf2 signaling pathway.. Cartilage 2021;13(2_suppl):238S-53S.
- Pauwels FE, McClure SR, Amin V, Van Sickle D, Evans RB. Effects of extracorporeal shock wave therapy and radial pressure wave therapy on elasticity and microstructure of equine cortical bone.. Am J Vet Res 2004;65(2):207-12.
- Bischofberger AS, Ringer SK, Geyer H, Imboden I, Ueltschi G, Lischer CJ. Histomorphologic evaluation of extracorporeal shock wave therapy of the fourth metatarsal bone and the origin of the suspensory ligament in horses without lameness.. Am J Vet Res 2006;67(4):577-82.
- Frisbie DD, Kawcak CE, McIlwraith CW. Evaluation of the effect of extracorporeal shock wave treatment on experimentally induced osteoarthritis in middle carpal joints of horses.. Am J Vet Res 2009;70(4):449-54.
- Wang C-J, Huang H-Y, Pai C-H. Shock wave-enhanced neovascularization at the tendon-bone junction: an experiment in dogs.. J Foot Ankle Surg 2002;41(1):16-22.
- Kersh KD, McClure SR, Van Sickle D, Evans RB. The evaluation of extracorporeal shock wave therapy on collagenase induced superficial digital flexor tendonitis.. Vet Comp Orthop Traumatol 2006;19(2):99-105.
- Alves ALG, da Fonseca BPA, Amorim RL, Thomassian A, Hussni CA, Nicoletti JLM. Effects of extracorporeal shock wave treatment on equine tendon healing.. ISMST 2006;1(12):2006.
- McClure SR, VanSickle D, Evans R, Reinertson EL, Moran L. The effects of extracorporeal shock-wave therapy on the ultrasonographic and histologic appearance of collagenase-induced equine forelimb suspensory ligament desmitis.. Ultrasound Med Biol 2004;30(4):461-7.
- Caminoto EH, Alves AL, Amorim RL, Thomassian A, Hussni CA, Nicoletti JL. Ultrastructural and immunocytochemical evaluation of the effects of extracorporeal shock wave treatment in the hind limbs of horses with experimentally induced suspensory ligament desmitis.. Am J Vet Res 2005;66(5):892-6.
- Wang CGW, Yang KD. Biological mechanisms of musculoskeletal shockwaves.. ISMST 2006;1:5-11.
- Meirer R, Kamelger FS, Huemer GM, Wanner S, Piza-Katzer H. Extracorporal shock wave may enhance skin flap survival in an animal model.. Br J Plast Surg 2005;58(1):53-7.
- Meirer R, Kamelger FS, Piza-Katzer H. Shock wave therapy: an innovative treatment method for partial thickness burns.. Burns 2005;31(7):921-2.
- Snyder R, Galiano R, Mayer P, Rogers LC, Alvarez O, Sanuwave TI. Diabetic foot ulcer treatment with focused shockwave therapy: two multicentre, prospective, controlled, double-blinded, randomised phase III clinical trials.. J Wound Care 2018;27(12):822-36.
- Silveira A, Koenig JB, Arroyo LG, Trout D, Moens NMM, LaMarre J. Effects of unfocused extracorporeal shock wave therapy on healing of wounds of the distal portion of the forelimb in horses.. Am J Vet Res 2010;71(2):229-34.
- Morgan DD, McClure S, Yaeger MJ, Schumacher J, Evans RB. Effects of extracorporeal shock wave therapy on wounds of the distal portion of the limbs in horses.. J Am Vet Med Assoc 2009;234(9):1154-61.
- Johnson JE, McClure SR, Liskey CC. Shockwave therapy for treatment of a burn injury in a horse.. Equine Vet Educ 2010;22(2):67-72.
- Norvall A, Allen AK, Johns S, Giguère S, Selberg KT. Diagnosis, treatment, and outcome of hindlimb proximal suspensory desmopathy in sport horses: 75 cases (2008-2014).. Proc Am Assoc Equine Practnrs 2015;61:358.
- Lischer CJ, Ringer SK, Schnewlin M, Imboden I, Fürst A, Stöckli M. Treatment of chronic proximal suspensory desmitis in horses using focused electrohydraulic shockwave therapy.. Schweiz Arch Tierheilkd 2006;148(10):561-8.
- Imboden I, Waldern NM, Wiestner T, Lischer CJ, Ueltschi G, Weishaupt MA. Short term analgesic effect of extracorporeal shock wave therapy in horses with proximal palmar metacarpal/plantar metatarsal pain.. Vet J 2009;179(1):50-9.
- Yocom AF, Bass LD. Review of the application and efficacy of extracorporeal shockwave therapy in equine tendon and ligament injuries.. Equine Vet Educ 2019;31(5):271-7.
- Osborne C. Does extracorporeal shockwave therapy or radial pressure wave therapy improve return to function over conservative and/or surgical management in horses with proximal suspensory desmitis?. Equine Vet Educ 2021;33(5):278-80.
- Barrett MF, Manchon PT, Hersman J, Kawcak CE. Magnetic resonance imaging findings of the proximal metacarpus in quarter horses used for cutting: retrospective analysis of 32 horses 2009-2012.. Equine Vet J 2018;50(2):172-8.
- Barrett MF, Selberg KT, Johnson SA, Hersman J, Frisbie DD. High field magnetic resonance imaging contributes to diagnosis of equine distal tarsus and proximal metatarsus lesions: 103 horses.. Vet Radiol Ultrasound 2018;59(5):587-96.
- Dahlberg JA, McClure SR, Evans RB, Reinertson EL. Force platform evaluation of lameness severity following extracorporeal shock wave therapy in horses with unilateral forelimb lameness.. J Am Vet Med Assoc 2006;229(1):100-3.
- Kusnierczak D, Brocai DR, Vettel U, Loew M. The influence of extracorporeal shock-wave (ESWA) on the biological behavior of bone cells in vitro.. ISMST 2000;96:1.
- Haussler KK, King MR. 18 - physical rehabilitation.. Joint disease in the horse 2016;p. 243-69.
- Allen A, Johns S, Hyman S, Sislak MD, Dais S, Amory J. How to diagnose and treat Back pain in the horse.. Proc Am Ass Equine Practnrs 2010;56:384-8.
- McClure S, Weinberger T. Extracorporeal shock wave therapy: clinical applications and regulation.. Clin Tech Equine Pract 2003;2(4):358-67.
- McClure S, Dahlberg J, Abed J, Evans R, Yaeger M. Continuing study of analgesia resulting from extracorporeal shock wave therapy.. Proc Am Assoc Equine Practnrs 2006;52:583.
- 2022 United States equestrian federation, Inc.. RuleBook.. Lexington, Kentucky: United States Equestrian Federation, Inc.; 2021.
- Federation Equestre Internationale. Eventing rules.. Lexington, Kentucky: Federation Equestre Internationale; 2021.
- Association of Racing Commissioners International. The Association of Racing Commissioners International's model rules of racing.. Lexington, Kentucky: Association of Racing Commissioners International; 2021.
- Tuncer M, Erdogan BA, Yazici O, Sahin C, Altin G, Faydaci G. Does extracorporeal shock wave lithotripsy cause hearing impairment?. Urology 2014;84(1):12-5.
- Kieves NR, MacKay CS, Adducci K, Rao S, Goh C, Palmer RH. High energy focused shock wave therapy accelerates bone healing. A blinded, prospective, randomized canine clinical trial.. Vet Comp Orthop Traumatol 2015;28(6):425-32.
- Tu J, Matula TJ, Bailey MR, Crum LA. Evaluation of a shock wave induced cavitation activity both in vitro and in vivo.. Phys Med Biol 2007;52(19):5933-44.
- Bani D, Quattrini Li A, Freschi G, Russo GL. Histological and ultrastructural effects of ultrasound-induced cavitation on human skin adipose tissue.. Plast Reconstr Surg Glob Open 2013;1(6):e41.
- Raabe O, Shell K, Goessl A, Crispens C, Delhasse Y, Eva A. Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro.. Am J Stem Cells 2013;2(1):62-73.
- Seabaugh KA, Thoresen M, Giguere S. Extracorporeal shockwave therapy increases growth factor release from equine platelet-rich plasma In vitro.. Front Vet Sci 2017;4:205.
- Colbath AC, Kisiday JD, Phillips JN, Goodrich LR. Can extracorporeal shockwave promote osteogenesis of equine bone marrow-derived mesenchymal stem cells In vitro?. Stem Cells Dev 2020;29(2):110-8.
- McClure S. Extracorporeal shock wave therapy: what? Why? Safety?. Lung 2003;260:460.
Citations
This article has been cited 1 times.- Boado A, Pollard D, Dyson S. Retrospective Analysis of Suspensory Ligament Branch Injuries in 70 Dressage Horses. Animals (Basel) 2025 Oct 23;15(21).
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