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The Annals of otology, rhinology, and laryngology2009; 118(4); 287-291; doi: 10.1177/000348940911800409

Equine versus bovine pericardium in transmeatal underlay myringoplasty.

Abstract: Many different grafting materials have been proposed in myringoplasty. The aim of this study was to evaluate the results obtained in transmeatal underlay myringoplasty using bovine and equine pericardium. The results were compared with those obtained by using autologous temporalis fascia. Methods: The study group consisted of 52 patients with tympanic perforation. Twenty-nine patients were randomly selected for treatment with bovine pericardium and 23 for equine pericardium. A group of 14 patients was treated with autologous temporalis fascia. Results: Closure of the perforation was achieved in 19 of 29 patients (66%) treated with bovine pericardium, in 19 of 23 (83%) treated with equine pericardium, and in 13 of 14 (93%) treated with autologous fascia. The best functional results in patients who gained closure of the perforation were obtained by means of equine pericardium. Conclusions: The overall long-term tympanic closure rate demonstrates that equine pericardium has a greater take rate than bovine pericardium. The results obtained are inferior to those obtained with autologous fascia, but this technique is less aggressive. The higher success rate with equine pericardium may be due to the fact that it is thinner and easier to handle and model than bovine pericardium.
Publication Date: 2009-05-26 PubMed ID: 19462850DOI: 10.1177/000348940911800409Google Scholar: Lookup
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  • Journal Article
  • Randomized Controlled Trial

Summary

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This research investigates the comparative outcomes of using bovine and equine pericardium in a specific type of ear surgery called transmeatal underlay myringoplasty. Results reveal that equine pericardium has a higher success rate than bovine pericardium, although both are less successful than utilizing autologous fascia. The researchers attribute the higher success rate of equine pericardium to its relatively thinner constitution and easier handling and modeling features.

Objective of the Research

The primary goal of this study was to examine the efficacy of bovine and equine pericardium when used in transmeatal underlay myringoplasty. This involved a comparative evaluation of both types of pericardium to verify their usefulness and success rates in the procedure. The results were put into perspective by comparing them to the outcomes of using autologous temporalis fascia, a commonly used grafting material in this surgical procedure.

Research Methods

  • A group of 52 patients, all of whom had tympanic perforations, constituted the study sample.
  • The patients were divided into three groups: one treated with bovine pericardium, another with equine pericardium, and a third with autologous temporalis fascia.
  • Outcome measures included whether the used material successfully sealed the perforation and how well the patients recovered post-surgery.

Results of the Research

  • The research showed variable degrees of success across the application of different grafting materials. The autologous fascia group realized the highest success rate, with a 93% closure rate. The equine pericardium and bovine pericardium groups recorded a success rate of 83% and 66%, respectively.
  • Patients who were treated with equine pericardium showed better functional results than those treated with bovine pericardium.

Conclusion

  • In terms of long-term tympanic closure, equine pericardium demonstrated a higher take-up rate than bovine pericardium.
  • Both equine and bovine pericardium proved to be less effective than autologous fascia. However, the use of pericardium results in a less invasive technique than the procedure involving autologous fascia.
  • The higher success rates realized with equine pericardium were accredited to its thinner structure and easier handling, which make it a more malleable material for the procedure.

In conclusion, the research suggests that equine pericardium shows potential as a viable alternative to bovine pericardium in transmeatal underlay myringoplasty, although it is not as effective as using autologous fascia.

Cite This Article

APA
Albera R, Dagna F, Lacilla M, Canale A. (2009). Equine versus bovine pericardium in transmeatal underlay myringoplasty. Ann Otol Rhinol Laryngol, 118(4), 287-291. https://doi.org/10.1177/000348940911800409

Publication

ISSN: 0003-4894
NlmUniqueID: 0407300
Country: United States
Language: English
Volume: 118
Issue: 4
Pages: 287-291

Researcher Affiliations

Albera, Roberto
  • Department of Otorhinolaryngology, San Giovanni Battista Hospital, Turin, Italy.
Dagna, Federico
    Lacilla, Michelangelo
      Canale, Andrea

        MeSH Terms

        • Adolescent
        • Adult
        • Aged
        • Animals
        • Auditory Threshold
        • Bone Conduction
        • Cattle
        • Child
        • Child, Preschool
        • Fascia / transplantation
        • Female
        • Horses
        • Humans
        • Male
        • Middle Aged
        • Myringoplasty / methods
        • Pericardium / transplantation
        • Transplantation, Autologous
        • Tympanic Membrane Perforation / surgery
        • Young Adult

        Citations

        This article has been cited 6 times.
        1. Ali MA, Shahabuddin M, Kumari V, Ahamed DBS, Alam S. Success Rate of Type I Tympanoplasty Using Temporalis Fascia by Underlay Technique in Safe Mucosal COM in KMCH, Katihar. Indian J Otolaryngol Head Neck Surg 2022 Dec;74(Suppl 3):4087-4090.
          doi: 10.1007/s12070-021-02841-0pubmed: 36742551google scholar: lookup
        2. Elassal AA, Al-Radi OO, Zaher ZF, Dohain AM, Abdelmohsen GA, Mohamed RS, Fatani MA, Abdelmotaleb ME, Noaman NA, Elmeligy MA, Eldib OS. Equine pericardium: a versatile alternative reconstructive material in congenital cardiac surgery. J Cardiothorac Surg 2021 Apr 23;16(1):110.
          doi: 10.1186/s13019-021-01494-ypubmed: 33892770google scholar: lookup
        3. Zouhair S, Sasso ED, Tuladhar SR, Fidalgo C, Vedovelli L, Filippi A, Borile G, Bagno A, Marchesan M, Giorgio R, Gregori D, Wolkers WF, Romanato F, Korossis S, Gerosa G, Iop L. A Comprehensive Comparison of Bovine and Porcine Decellularized Pericardia: New Insights for Surgical Applications. Biomolecules 2020 Feb 28;10(3).
          doi: 10.3390/biom10030371pubmed: 32121155google scholar: lookup
        4. Villar-Fernandez MA, Lopez-Escamez JA. Outlook for Tissue Engineering of the Tympanic Membrane. Audiol Res 2015 Jan 21;5(1):117.
          doi: 10.4081/audiores.2015.117pubmed: 26557361google scholar: lookup
        5. de Dorlodot C, De Bie G, Deggouj N, Decat M, Gérard JM. Are bovine pericardium underlay xenograft and butterfly inlay autograft efficient for transcanal tympanoplasty?. Eur Arch Otorhinolaryngol 2015 Feb;272(2):327-31.
          doi: 10.1007/s00405-013-2855-8pubmed: 24337878google scholar: lookup
        6. Canale A, Boldreghini M, Abboud I, Peluso P, Vestrini E, Riva G, Albera A. Cartilage graft and temporal muscle fascia graft in revision myringoplasty: a comparison of anatomical and functional results with an innovative surgical technique. Front Neurol 2024;15:1497162.
          doi: 10.3389/fneur.2024.1497162pubmed: 39925639google scholar: lookup