Erratum: Author Correction: Improved reference genome for the domestic horse increases assembly contiguity and composition.
Abstract: [This corrects the article DOI: 10.1038/s42003-018-0199-z.].
Publication Date: 2019-09-11 PubMed ID: 31531403PubMed Central: PMC6739301DOI: 10.1038/s42003-019-0591-3Google Scholar: Lookup
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- Published Erratum
Summary
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The research article corrects and improves the reference genome for the domestic horse, enhancing the assembly contiguity and composition.
Background of the Research paper
- This research paper is essentially a correction or erratum to a previous article published under the DOI: 10.1038/s42003-018-0199-z.
- The original article focused on enhancing the knowledge and understanding of the domestic horse’s genetic makeup by working on its reference genome.
- The reference genome serves as a standardized genetic map, representing the entirety of the horse’s genetic material.
Details of the Correction
- Improvements claimed relate to two key aspects of the reference genome – assembly contiguity and composition.
- Assembly contiguity refers to the quality and accuracy of the sequential arrangement of the genes and other genetic markers within the genome.
- Increased assembly contiguity means that the corrected version of the horse’s reference genome presents a more accurate sequence of genes, possibly resulting in fewer gaps or missing links between genetic markers.
- ‘Composition’ likely refers to the genomes make-up in terms of the arrangement and proportion of different genetic elements like genes, chromosomes, etc.
- Thus, improvements in composition could indicate that the corrected genome represents a more accurate representation of the horse’s actual genetic makeup.
Implications of the Correction
- These corrections not only improve the quality of the reference genome but also have practical implications for studies involving the domestic horse’s genetics.
- Better understanding of the horse’s genetic material can aid in studies aimed at understanding and treating genetic diseases in horses, improving breeding strategies, and even in broader studies of mammalian genetics given the evolutionary relationship between horses and other mammals.
Cite This Article
APA
Kalbfleisch TS, Rice ES, DePriest MS, Walenz BP, Hestand MS, Vermeesch JR, O'Connell BL, Fiddes IT, Vershinina AO, Saremi NF, Petersen JL, Finno CJ, Bellone RR, McCue ME, Brooks SA, Bailey E, Orlando L, Green RE, Miller DC, Antczak DF, MacLeod JN.
(2019).
Erratum: Author Correction: Improved reference genome for the domestic horse increases assembly contiguity and composition.
Commun Biol, 2, 342.
https://doi.org/10.1038/s42003-019-0591-3 Publication
Researcher Affiliations
- 1Department of Biochemistry and Molecular Genetics, School of Medicine, University of Louisville, Louisville, KY 40292 USA.
- 2Department of Biomolecular Engineering, UC Santa Cruz, Santa Cruz, CA 95064 USA.
- 1Department of Biochemistry and Molecular Genetics, School of Medicine, University of Louisville, Louisville, KY 40292 USA.
- 3Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 USA.
- 4Center for Human Genetics, Katholieke University Leuven (KU Leuven), 3000 Leuven, Belgium.
- 4Center for Human Genetics, Katholieke University Leuven (KU Leuven), 3000 Leuven, Belgium.
- 2Department of Biomolecular Engineering, UC Santa Cruz, Santa Cruz, CA 95064 USA.
- 16Present Address: Medical and Molecular Genetics, Oregon Health and Science University, Portland, OR 97239 USA.
- 2Department of Biomolecular Engineering, UC Santa Cruz, Santa Cruz, CA 95064 USA.
- 510x Genomics, Inc., Pleasanton, CA 94566 USA.
- 6Department of Ecology and Evolutionary Biology, UC Santa Cruz, Santa Cruz, CA 95064 USA.
- 2Department of Biomolecular Engineering, UC Santa Cruz, Santa Cruz, CA 95064 USA.
- 7Department of Animal Science, University of Nebraska - Lincoln, Lincoln, NE 68583-0908 USA.
- 8Department of Population Health and Reproduction, University of California, Davis, CA 95616 USA.
- 8Department of Population Health and Reproduction, University of California, Davis, CA 95616 USA.
- 9Veterinary Genetics Laboratory, University of California, Davis, CA 95616 USA.
- 10Department of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108 USA.
- 11UF Genetics Institute, Department of Animal Sciences, University of Florida, Gainesville, FL 32611 USA.
- 12Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546 USA.
- 13Centre for GeoGenetics, Natural History Museum of Denmark, 1350K Copenhagen, Denmark.
- Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse UMR 5288, Université de Toulouse, CNRS, Université Paul Sabatier, Toulouse, France.
- 2Department of Biomolecular Engineering, UC Santa Cruz, Santa Cruz, CA 95064 USA.
- 15Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
- 15Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
- 12Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546 USA.
Grant Funding
- K01 OD015134 / NIH HHS
- L40 TR001136 / NCATS NIH HHS
Citations
This article has been cited 2 times.- Martin FJ, Gall A, Szpak M, Flicek P. Accessing Livestock Resources in Ensembl. Front Genet 2021;12:650228.
- Leite RO, Albertino LG, Sperandio LMS, Campos F, Campos R, Borges AS, Oliveira-Filho JP. Evaluation of variants in the ENTPD1 and ENTPD2 genes in athletic horses with exercise-induced pulmonary haemorrhage. BMC Vet Res 2024 Aug 6;20(1):346.
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