Evaluation of equine breeding farm characteristics as risk factors for development of Rhodococcus equi pneumonia in foals.
Abstract: To identify farm characteristics as risk factors for the development of Rhodococcus equi pneumonia in foals. Methods: Prospective matched case-control study. Methods: 2,764 foals on 64 equine breeding farms with 9,991 horses. Methods: During 1997, participating veterinarians completed paired data collection forms, 1 for a farm with > or = 1 foal with R equi pneumonia and 1 for an unaffected control farm. Matched data were compared by use of conditional logistic regression analysis. Results: Farm characteristics found in bivariate analyses to be associated with increased risk for pneumonia caused by R equi in foals included > 200 farm acres, > or = 60 acres used in the husbandry of horses, > 160 horses, > or = 10 mares housed permanently on the farm (resident mares), > 17 foals, > 0.25 foals/acre, and the presence of transient mares (mares brought temporarily to the farm for breeding or foaling) and their foals. Affected farms were significantly more likely to be > 200 acres in size and have > or = 10 resident dam-foal pairs, whereas control farms were significantly more likely to have > or = 75% of their dam-foal pairs housed permanently on the farm. Conclusions: Breeding farms with large acreage, a large number of mares and foals, high foal density, and a population of transient mares and foals are at high risk for foals developing pneumonia caused by R equi.
Publication Date: 2003-02-25 PubMed ID: 12597420DOI: 10.2460/javma.2003.222.467Google Scholar: Lookup
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- Evaluation Study
- Journal Article
- Research Support
- Non-U.S. Gov't
- Research Support
- U.S. Gov't
- Non-P.H.S.
Summary
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This research article examines the characteristics of horse breeding farms that increase the risk of newborn horses, or foals, developing a type of pneumonia caused by the bacterium Rhodococcus equi.
Methods
- The research was conducted on 64 equine breeding farms with a total of 9,991 horses, including 2,764 foals.
- The researchers conducted a prospective matched case-control study. This means they compared pairs of farms where one had at least one foal with R. equi pneumonia and the other did not (the control).
- The data was collected in 1997 by veterinarians who filled out forms for each pair of farms, and was then analysed using conditional logistic regression analysis.
Results
- Findings revealed that farms with greater than 200 acres of land, over 60 acres used for horse husbandry, more than 160 horses, at least 10 permanent resident mares, more than 17 foals, over 0.25 foals per acre, and the presence of transient mares (those brought temporarily for breeding or foaling) and their foals, are more likely to have foals develop R. equi pneumonia.
- Farms affected by R. equi were also more likely to be greater than 200 acres in size and have more than 10 resident dam-foal pairs.
- In contrast, control farms were more likely to have at least 75% of their dam-foal pairs as permanent residents.
Conclusions
- The study concluded that breeding farms with large acreage, a large number of mares and foals, high foal density, and a population of transient mares and their foals are at high risk for foals developing pneumonia caused by R. equi.
- This research is invaluable for equine breeders, equine health professionals and researchers as it identifies key risk factors which they can use in their prevention strategies against Rhodococcus equi pneumonia in foals.
Cite This Article
APA
Chaffin MK, Cohen ND, Martens RJ.
(2003).
Evaluation of equine breeding farm characteristics as risk factors for development of Rhodococcus equi pneumonia in foals.
J Am Vet Med Assoc, 222(4), 467-475.
https://doi.org/10.2460/javma.2003.222.467 Publication
Researcher Affiliations
- Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4475, USA.
MeSH Terms
- Actinomycetales Infections / epidemiology
- Actinomycetales Infections / etiology
- Actinomycetales Infections / microbiology
- Actinomycetales Infections / veterinary
- Animal Husbandry / methods
- Animals
- Animals, Newborn
- Case-Control Studies
- Female
- Horse Diseases / epidemiology
- Horse Diseases / etiology
- Horse Diseases / microbiology
- Horses
- Logistic Models
- Male
- Pneumonia, Bacterial / epidemiology
- Pneumonia, Bacterial / etiology
- Pneumonia, Bacterial / microbiology
- Pneumonia, Bacterial / veterinary
- Population Density
- Prospective Studies
- Rhodococcus equi / immunology
- Rhodococcus equi / pathogenicity
- Risk Factors
- Texas / epidemiology
Citations
This article has been cited 5 times.- Migliorisi A, Barger A, Austin S, Foreman JH, Wilkins P. Hyponatremia in horses with septic pneumopathy. J Vet Intern Med 2022 Sep;36(5):1820-1826.
- Álvarez-Narváez S, Berghaus LJ, Morris ERA, Willingham-Lane JM, Slovis NM, Giguere S, Cohen ND. A Common Practice of Widespread Antimicrobial Use in Horse Production Promotes Multi-Drug Resistance. Sci Rep 2020 Jan 22;10(1):911.
- McQueen CM, Whitfield-Cargile CM, Konganti K, Blodgett GP, Dindot SV, Cohen ND. TRPM2 SNP genotype previously associated with susceptibility to Rhodococcus equi pneumonia in Quarter Horse foals displays differential gene expression identified using RNA-Seq. BMC Genomics 2016 Dec 5;17(1):993.
- McQueen CM, Doan R, Dindot SV, Bourquin JR, Zlatev ZZ, Chaffin MK, Blodgett GP, Ivanov I, Cohen ND. Identification of genomic loci associated with Rhodococcus equi susceptibility in foals. PLoS One 2014;9(6):e98710.
- Muscatello G, Anderson GA, Gilkerson JR, Browning GF. Associations between the ecology of virulent Rhodococcus equi and the epidemiology of R. equi pneumonia on Australian thoroughbred farms. Appl Environ Microbiol 2006 Sep;72(9):6152-60.
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