Evidence-based immunization in horses.
Abstract: Evidence of vaccine efficacy is essential for practitioners when giving advice to clients about the relative merits of different vaccines or when trying to evaluate the economic benefits of instituting a vaccine program. In equine veterinary medicine, this sort of data, which are necessary to make informed decisions about vaccine use and effectiveness, are often not available. Veterinarians need to consider the epidemiology of the disease in question, the type of vaccine that they are administering to the animal, the immunologic constraints of the vaccine technology, and the available evidence of efficacy when they are evaluating which vaccine to use or whether to vaccinate at all.
Publication Date: 2007-07-10 PubMed ID: 17616324DOI: 10.1016/j.cveq.2007.04.003Google Scholar: Lookup
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Summary
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This research article discusses the importance of evidence-based vaccination in horses, highlighting the scarcity of data necessary for informed decision-making on vaccine use and effectiveness in equine medicine. It emphasizes the need for veterinarians to consider disease epidemiology, vaccine type, and immunologic constraints, along with vaccine efficacy evidence when deciding on vaccination strategies.
Evidence for Vaccine Efficacy in Equine Medicine
- The article kicks off by noting the significance of having concrete evidence of vaccine efficacy. This information is essential in helping veterinary practitioners when advising a client about the benefits of different vaccines. It’s also critical when trying to evaluate the economic advantages of starting a vaccination program.
- However, the article puts it clear that such vital information tends to be insufficient in equine veterinary medicine. This lack of data is a hurdle to making informed decisions regarding vaccine use and their effectiveness.
Necessary Considerations in Vaccine Administration
- Given the scarcity of data on vaccine efficacy, veterinarians have to make the most out of the available information. They must take into account various factors before deciding which vaccine to use or whether they should administer a vaccine at all.
- One of these factors is the epidemiology of the disease in question. Understanding the disease’s distribution, risk factors, and the population it often affects can help in tailoring the best vaccination strategy.
- Another factor to regard is the type of vaccine to be used. Different vaccines stimulate the immune response differently. It’s therefore paramount to understand how a particular vaccine works before administration.
- The immunologic constraints of the vaccine technology are another crucial consideration. Some vaccines may come with limitations on their efficacy based on the technology used in their production.
- Finally, available evidence on efficacy is another essential consideration. Regardless of how scanty it might be, any evidence available should be used to make the best judgment.
Cite This Article
APA
Barquero N, Gilkerson JR, Newton JR.
(2007).
Evidence-based immunization in horses.
Vet Clin North Am Equine Pract, 23(2), 481-508.
https://doi.org/10.1016/j.cveq.2007.04.003 Publication
Researcher Affiliations
- Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, United Kingdom.
MeSH Terms
- Animals
- Clinical Trials as Topic
- Horse Diseases / immunology
- Horse Diseases / prevention & control
- Horses
- Risk Assessment
- Treatment Outcome
- Vaccination / adverse effects
- Vaccination / methods
- Vaccination / veterinary
- Vaccines / administration & dosage
- Vaccines / adverse effects
Citations
This article has been cited 1 times.- Carnet F, Perrin-Cocon L, Paillot R, Lotteau V, Pronost S, Vidalain PO. An inventory of adjuvants used for vaccination in horses: the past, the present and the future. Vet Res 2023 Mar 2;54(1):18.
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